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Economic evaluation of endovascular treatment for acute ischaemic stroke in Thailand
Conclusions EVT represents good value for money in the Thai context, both when provided to patients eligible for intravenous alteplase, and when provided alone to those who are ineligible for intravenous alteplase.
Source: BMJ Open - September 27, 2022 Category: General Medicine Authors: Rattanavipapong, W., Worakijthamrongchai, T., Soboon, B., Luankongsomchit, V., Kongmuangpuk, M., Isaranuwatchai, W., Teerawattananon, Y., Nilanont, Y. Tags: Open access, Health economics Source Type: research

Health economic evaluation of the 'Flying Intervention Team as a novel stroke care concept for rural areas: study protocol of the TEMPiS-GÖA study
The objective of the present paper is to describe the methods for the economic evaluation (TEMPiS-Gesundheitsökonomische Analyse (TEMPiS-GÖA)) alongside the TEMPiS-FIT study to determine whether the new form of care is cost-effective compared with standard care. Methods and analysis The within-trial cost-effectiveness analysis (CEA) and cost–utility analysis (CUA) will be performed from a statutory health insurance perspective as well as from a societal perspective over the time horizon of 12 months after the patients’ hospital discharge. Direct costs from outpatient and inpatient care are coll...
Source: BMJ Open - September 20, 2022 Category: General Medicine Authors: Coors, M., Flemming, R., Schüttig, W., Hubert, G. J., Hubert, N. D., Sundmacher, L. Tags: Open access, Health economics Source Type: research

Economic impact of the first pass effect in mechanical thrombectomy for acute ischaemic stroke treatment in Spain: a cost-effectiveness analysis from the national health system perspective
Conclusion Achieving FPE after MT can lead to better health outcomes per AIS patient and important cost savings for the Spanish NHS.
Source: BMJ Open - September 1, 2022 Category: General Medicine Authors: Gonzalez Diaz, E., Rodriguez-Paz, C., Fernandez-Prieto, A., Martinez-Galdamez, M., Martinez-Moreno, R., Ortega Quintanilla, J., Tomasello, A., Zamarro, J., Liebeskind, D., Zaidat, O. O., Mueller-Kronast, N. H. Tags: Open access, Health economics Source Type: research

Cost-effectiveness of follow-up invasive coronary angiography after percutaneous coronary stenting: a real-world observational cohort study in Japan
Conclusions FUICA increased the costs but did not improve clinical benefits. Thus, FUICA is not economically more attractive than CF alone. Trial registration number UMIN000039768.
Source: BMJ Open - August 30, 2022 Category: General Medicine Authors: Shiina, T., Goto-Hirano, K., Takura, T., Daida, H. Tags: Open access, Health economics Source Type: research

Decreasing rates of cost-related medication non-adherence by age advancement among American generational cohorts 2004-2014: a longitudinal study
Conclusion The paradox of decreasing CRN rates, independent of disease burden, income and insurance status, suggests populations’ CRN behaviours change as Americans age, bearing implications to social policy.
Source: BMJ Open - May 6, 2022 Category: General Medicine Authors: Zhang, J., Bhaumik, D., Meltzer, D. Tags: Open access, Health economics Source Type: research

Cost-effective analysis of mechanical thrombectomy alone in the treatment of acute ischaemic stroke: a Markov modelling study
Conclusions MT alone was cost-effective compared with MT with alteplase in China. However, cautions are needed to extend this conclusion to regions outside of China.
Source: BMJ Open - April 6, 2022 Category: General Medicine Authors: Han, M., Qin, Y., Tong, X., Ji, L., Zhao, S., Liu, L., Chen, J., Liu, A. Tags: Open access, Health economics Source Type: research

Hypertension in the South African public healthcare system: a cost-of-illness and burden of disease study
Conclusion Hypertension exerts a heavy health and economic burden on South Africa. Establishing cost-effective best practice guidelines for hypertension treatment requires further research. Such research will be essential if South Africa is to make progress in its efforts to implement universal healthcare.
Source: BMJ Open - February 22, 2022 Category: General Medicine Authors: Kohli-Lynch, C. N., Erzse, A., Rayner, B., Hofman, K. J. Tags: Open access, Health economics Source Type: research

Protocol for the economic evaluation of the China Salt Substitute and Stroke Study (SSaSS)
This study protocol describes the planned within-trial economic evaluation of a low-sodium salt substitute intervention designed to reduce the risk of stroke in China. Methods and analyses The economic evaluation will be conducted alongside the Salt Substitute and Stroke Study: a 5-year large scale, cluster randomised controlled trial. The outcomes of interest are quality of life measured using the EuroQol-5-Dimensions and major adverse cardiovascular events. Costs will be estimated from a healthcare system perspective and will be sought from the routinely collected data available within the New Rural Cooperative Medical ...
Source: BMJ Open - July 20, 2021 Category: General Medicine Authors: Li, K.-C., Tian, M., Neal, B., Huang, L., Yu, J., Liu, Y., Yin, X., Zhang, X., Wu, Y., Li, N., Elliott, P., Yan, L., Labarthe, D., Hao, Z., Shi, J., Feng, X., Zhang, J., Zhang, Y., Zhang, R., Zhou, B., Li, Z., Sun, J., Zhao, Y., Yu, Y., Si, L., Lung, T. Tags: Open access, Health economics Source Type: research

Antithrombotic stewardship: a multidisciplinary team approach towards improving antithrombotic therapy outcomes during and after hospitalisation: a study protocol
In this study, the effect of the implementation of a multidisciplinary antithrombotic team is compared with usual care using a pre-post study design. The study is performed at the Erasmus University Medical Center Rotterdam and the Reinier de Graaf Hospital Delft. Patients who are or will be treated with antithrombotics are included in the study. We aim to include 1900 patients, 950 in each hospital. Primary outcome is the proportion of patients with a composite end point consisting of ≥1 bleeding or ≥1 thrombotic event from the beginning of antithrombotic therapy (or hospitalisation) until 3 months after hospit...
Source: BMJ Open - December 19, 2016 Category: Journals (General) Authors: Dreijer, A. R., Kruip, M. J. H. A., Diepstraten, J., Polinder, S., Brouwer, R., Leebeek, F. W. G., Vulto, A. G., van den Bemt, P. M. L. A. Tags: Open access, Epidemiology, Haematology (incl blood transfusion), Health economics Protocol Source Type: research

Estimating the economic burden of cardiovascular events in patients receiving lipid-modifying therapy in the UK
Conclusions Revascularisation and myocardial infarction were associated with the highest incremental costs following a CV event. On the basis of real-world data, the economic burden of CV events in the UK is substantial, particularly among those with greater comorbidity burden.
Source: BMJ Open - August 4, 2016 Category: Journals (General) Authors: Danese, M. D., Gleeson, M., Kutikova, L., Griffiths, R. I., Azough, A., Khunti, K., Seshasai, S. R. K., Ray, K. K. Tags: Open access, Cardiovascular medicine, Health economics, Health services research Source Type: research

The burden of stroke in the Netherlands: estimating quality of life and costs for 1 year poststroke
Conclusions We found lower patient costs and higher QoL than expected. This may be explained by the good state of health of our study population and by change in the Dutch healthcare system, which has led to considerable shorter hospitalisation poststroke. Future research must question the use of the EQ-5D-3L in a similar population due to ceiling effects. Trial registration number NTR3051.
Source: BMJ Open - November 27, 2015 Category: Journals (General) Authors: van Eeden, M., van Heugten, C., van Mastrigt, G. A. P. G., van Mierlo, M., Visser-Meily, J. M. A., Evers, S. M. A. A. Tags: Open access, Health economics Research Source Type: research

Overweight and obesity on the island of Ireland: an estimation of costs
Conclusions The costs are substantial, and urgent public health action is required in Ireland to address the problem of increasing prevalence of overweight and obesity, which if left unchecked will lead to unsustainable cost escalation within the health service and unacceptable societal costs.
Source: BMJ Open - March 16, 2015 Category: Journals (General) Authors: Dee, A., Callinan, A., Doherty, E., O'Neill, C., McVeigh, T., Sweeney, M. R., Staines, A., Kearns, K., Fitzgerald, S., Sharp, L., Kee, F., Hughes, J., Balanda, K., Perry, I. J. Tags: Open access, Epidemiology, Health economics Research Source Type: research