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Differences in acute ischaemic stroke in-hospital mortality across referral stroke hospitals in Spain: a retrospective, longitudinal observational study
Conclusions In the referral stroke hospitals of the Spanish National Health System, the overall adjusted in-hospital mortality decreased between 2003 and 2015. However, between-hospital variations in mortality persisted.
Source: BMJ Open - June 28, 2023 Category: General Medicine Authors: Estupinan-Romero, F., Pinilla Dominguez, J., Bernal-Delgado, E., on behalf of the Atlas VPM consortium Tags: Open access, Health services research Source Type: research

Validation of diagnosis of acute myocardial infarction and stroke in electronic medical records: a primary care cross-sectional study in Madrid, Spain (the e-MADVEVA Study)
Conclusion The validation results show that diagnoses of AMI and stroke in primary care EMRs constitute a helpful tool in epidemiological studies. The prevalence of AMI and stroke was lower than 2% in the population aged over 18 years.
Source: BMJ Open - June 12, 2023 Category: General Medicine Authors: de Burgos-Lunar, C., del Cura-Gonzalez, I., Cardenas-Valladolid, J., Gomez-Campelo, P., Abanades-Herranz, J. C., Lopez-de-Andres, A., Sotos-Prieto, M., Iriarte-Campo, V., Fuentes-Rodriguez, C. Y., Gomez-Coronado, R., Salinero-Fort, M. A. Tags: Open access, Cardiovascular medicine Source Type: research

Multidimensional analysis of sedentary behaviour and participation in Spanish stroke survivors (Part&Sed-Stroke): a protocol for a longitudinal multicentre study
Introduction Stroke survivors usually experience long-lasting functional, emotional and social consequences that might contribute to sedentary behaviour and participation restrictions, which are important targets to address during rehabilitation. However, the trajectory and inter-relationship between these factors are unknown. Methods and analysis Part&Sed is a research project based on an observational study design with 6 and 12 months of follow-ups in stroke survivors. In addition, a qualitative analysis of the impact of the stroke on the stroke survivor, validation of the Satisfaction with Daily Occupation-Occupati...
Source: BMJ Open - February 15, 2023 Category: General Medicine Authors: de Diego-Alonso, C., Alegre-Ayala, J., Buesa, A., Blasco-Abadia, J., Lopez-Royo, M. P., Roldan-Perez, P., Giner-Nicolas, R., Part&Sed-Stroke Collaborators Group, Gu&x0308;eita-Rodriguez, J., Fini, N. A., Domenech-Garcia, V., Bellosta-Lopez, P., Navarro, L Tags: Open access, Neurology Source Type: research

Economic impact of the first pass effect in mechanical thrombectomy for acute ischaemic stroke treatment in Spain: a cost-effectiveness analysis from the national health system perspective
Conclusion Achieving FPE after MT can lead to better health outcomes per AIS patient and important cost savings for the Spanish NHS.
Source: BMJ Open - September 1, 2022 Category: General Medicine Authors: Gonzalez Diaz, E., Rodriguez-Paz, C., Fernandez-Prieto, A., Martinez-Galdamez, M., Martinez-Moreno, R., Ortega Quintanilla, J., Tomasello, A., Zamarro, J., Liebeskind, D., Zaidat, O. O., Mueller-Kronast, N. H. Tags: Open access, Health economics Source Type: research

Allogeneic adipose tissue-derived mesenchymal stem cells in ischaemic stroke (AMASCIS-02): a phase IIb, multicentre, double-blind, placebo-controlled clinical trial protocol
Introduction Stroke is a serious public health problem, given it is a major cause of disability worldwide despite the spread of recanalisation therapies. Enhancement of brain plasticity with stem cell administration is a promising innovative therapy to reduce sequelae in these patients. Methods and analysis We have developed a phase IIb, multicentre, randomised, double-blind, placebo-controlled clinical trial protocol to evaluate the safety and efficacy of intravenous administration of allogeneic adipose tissue-derived mesenchymal stem cells (AD-MSCs) in patients with acute ischaemic stroke, concurrently with conventional...
Source: BMJ Open - August 9, 2021 Category: General Medicine Authors: de Celis-Ruiz, E., Fuentes, B., Moniche, F., Montaner, J., Borobia, A. M., Gutierrez-Fernandez, M., Diez-Tejedor, E. Tags: Open access, Neurology Source Type: research