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Statins for extension of disability-free survival and primary prevention of cardiovascular events among older people: protocol for a randomised controlled trial in primary care (STAREE trial)
Introduction The world is undergoing a demographic transition to an older population. Preventive healthcare has reduced the burden of chronic illness at younger ages but there is limited evidence that these advances can improve health at older ages. Statins are one class of drug with the potential to prevent or delay the onset of several causes of incapacity in older age, particularly major cardiovascular disease (CVD). This paper presents the protocol for the STAtins in Reducing Events in the Elderly (STAREE) trial, a randomised double-blind placebo-controlled trial examining the effects of statins in community dwelling o...
Source: BMJ Open - April 3, 2023 Category: General Medicine Authors: Zoungas, S., Curtis, A., Spark, S., Wolfe, R., McNeil, J. J., Beilin, L., Chong, T. T.-J., Cloud, G., Hopper, I., Kost, A., Nelson, M., Nicholls, S. J., Reid, C. M., Ryan, J., Tonkin, A., Ward, S. A., Wierzbicki, A., On behalf of STAREE investigator group Tags: Open access, Cardiovascular medicine Source Type: research

Safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding: protocol for a systematic review and meta-analysis
Introduction Dysphagia is a common functional disorder after stroke. Most patients post-stroke are incapable of oral feeding, which often leads to complications such as malnutrition, aspiration pneumonia and dehydration that seriously affect the quality of life of patients. Oropharyngeal muscle strength training is a major method of swallowing training, and recent studies have focused on healthy adults, elderly persons, and patients with head and neck cancer or neurodegenerative diseases; but there have been few studies on such training in patients with post-stroke dysphagia. Our study aims to systematically review the saf...
Source: BMJ Open - June 15, 2022 Category: General Medicine Authors: Gao, M., Wang, Y., Xu, L., Wang, X., Wang, H., Song, J., Yang, X., Zhou, F. Tags: Open access, Neurology Source Type: research

Is poor oral health a risk marker for incident cardiovascular disease hospitalisation and all-cause mortality? Findings from 172 630 participants from the prospective 45 and Up Study
Conclusions Tooth loss and, to a lesser extent, self-rated health of teeth and gums, are markers for increased risk of IHD, PVD and all-cause mortality. Tooth loss is also a marker for increased risk of HF.
Source: BMJ Open - August 29, 2016 Category: Journals (General) Authors: Joshy, G., Arora, M., Korda, R. J., Chalmers, J., Banks, E. Tags: Open access, Cardiovascular medicine, Dentistry and oral medicine, Epidemiology, Health services research Source Type: research

Associations between chronic diseases and choking deaths among older adults in the USA: a cross-sectional study using multiple cause mortality data from 2009 to 2013
Conclusions We suggest using overall choking instead of only food-related choking to better describe the associations between chronic diseases and choking.
Source: BMJ Open - November 12, 2015 Category: Journals (General) Authors: Wu, W.-S., Sung, K.-C., Cheng, T.-J., Lu, T.-H. Tags: Open access, Epidemiology, Geriatric medicine, Medical management, Public health, Respiratory medicine Research Source Type: research

A cross-sectional survey investigating the desensitisation of graphic health warning labels and their impact on smokers, non-smokers and patients with COPD in a London cohort
Conclusions GHWL are most effective in non-smokers and a desensitisation effect was observed in smokers and patients with COPD. As a consequence, a tailored and concerted public health approach to use such messages is required and ‘blindness’ deserves to be mentioned in this context because of an unexpectedly high-deterring impact.
Source: BMJ Open - July 4, 2014 Category: Journals (General) Authors: Ratneswaran, C., Chisnall, B., Drakatos, P., Sivakumar, S., Sivakumar, B., Barrecheguren, M., Douiri, A., Steier, J. Tags: Open access, Health policy, Public health, Respiratory medicine, Smoking and tobacco Research Source Type: research