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Outcomes After Endovascular Thrombectomy With or Without Alteplase in Routine Clinical Practice
This cohort study investigates the outcomes of combination endovascular thrombectomy with alteplase compared with endovascular thrombectomy alone for the treatment of patients with acute ischemic stroke attributable to large vessel occlusion.
Source: JAMA Neurology - June 13, 2022 Category: Neurology Source Type: research

Time for a New Perspective on Intracerebral Hemorrhage
More than 3 million people worldwide experience intracerebral hemorrhage (ICH) each year. Although the incidence of ICH is much lower than that of ischemic stroke, ICH imposes a 50% greater worldwide burden of disability. ICH has a 30-day case fatality rate of more than 40%, and most survivors are left with permanent disabilities. Because of the high likelihood of poor outcomes, physicians caring for patients with ICH tend to use clinical severity scores early on to estimate the risk of mortality or future disability to determine the aggressiveness of medical care and to guide conversations with patients ’ surrogates aro...
Source: JAMA Neurology - July 25, 2022 Category: Neurology Source Type: research

Association of Stroke and Cerebrovascular Pathologies With Scam Susceptibility in Older Adults
This cohort study examines the association of diverse cerebrovascular pathologies (globally and regionally) with scam susceptibility in older adults.
Source: JAMA Neurology - October 31, 2022 Category: Neurology Source Type: research

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants
This cohort study evaluates the risk of symptomatic intracranial hemorrhage associated with use of intravenous thrombolysis in patients with recent direct oral anticoagulant ingestion.
Source: JAMA Neurology - January 3, 2023 Category: Neurology Source Type: research

Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors
This cross-sectional study examines data from the UK Biobank to explore the association between focal epilepsy compared with stroke or migraine and the risk of developing dementia and how that risk is affected by modifiable cardiovascular risk factors.
Source: JAMA Neurology - March 27, 2023 Category: Neurology Source Type: research

Myocardial Infarction Bends the Curve of Age-Related Cognitive Decline
In this issue of JAMA Neurology, Johansen et al reported that there was an acceleration of age-related cognitive decline following acute myocardial infarction (MI). In an analysis of more than 30  000 persons pooled from 6 major US epidemiological cohort studies, the 1033 individuals who had an MI during study follow-up had a steeper annual decline in cognition after the MI compared with before the MI. As expected, all persons with or without MI had a small age-related annual decline in co gnition. This age dependence is a feature of most neuropsychological tests. However, after MI, the annual rate of decline accelerated...
Source: JAMA Neurology - May 30, 2023 Category: Neurology Source Type: research

Automated Large Vessel Occlusion Detection Software and Thrombectomy Treatment Times
This study attempts to determine whether automated computed tomography angiogram interpretation coupled with secure group messaging can improve in-hospital endovascular stroke therapy workflows.
Source: JAMA Neurology - September 18, 2023 Category: Neurology Source Type: research

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