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Source: JAMA Neurology
Condition: Atrial Fibrillation

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Total 17 results found since Jan 2013.

Inducers and Cardiovascular Risk —Potential Role for Lowered Drug Exposure—Reply
In Reply We thank Van der Linden and colleagues for their interest in our article, which describes the long-term cardiovascular risk associated with continued use of enzyme-inducing antiseizure medications (eiASMs). With respect to our mediation analysis, we considered incident dyslipidemia as a binary mediator variable, as opposed to a continuous variable of low-density lipoprotein cholesterol or total cholesterol, given its direct clinical relevance as the threshold over which treatment is initiated. However, we agree that future efforts at exploring a dose-dependent mediation between absolute and relative increases in l...
Source: JAMA Neurology - March 7, 2022 Category: Neurology Source Type: research

Myocardial Infarction Bends the Curve of Age-Related Cognitive Decline
In this issue of JAMA Neurology, Johansen et al reported that there was an acceleration of age-related cognitive decline following acute myocardial infarction (MI). In an analysis of more than 30  000 persons pooled from 6 major US epidemiological cohort studies, the 1033 individuals who had an MI during study follow-up had a steeper annual decline in cognition after the MI compared with before the MI. As expected, all persons with or without MI had a small age-related annual decline in co gnition. This age dependence is a feature of most neuropsychological tests. However, after MI, the annual rate of decline accelerated...
Source: JAMA Neurology - May 30, 2023 Category: Neurology Source Type: research