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Specialty: General Medicine
Source: The Lancet

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Total 200 results found since Jan 2013.

Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study
Publication date: Available online 17 September 2015 Source:The Lancet Author(s): Andrew Smyth, Koon K Teo, Sumathy Rangarajan, Martin O'Donnell, Xiaohe Zhang, Punam Rana, Darryl P Leong, Gilles Dagenais, Pamela Seron, Annika Rosengren, Aletta E Schutte, Patricio Lopez-Jaramillo, Ayetkin Oguz, Jephat Chifamba, Rafael Diaz, Scott Lear, Alvaro Avezum, Rajesh Kumar, Viswanathan Mohan, Andrzej Szuba, Li Wei, Wang Yang, Bo Jian, Martin McKee, Salim Yusuf Background Alcohol consumption is proposed to be the third most important modifiable risk factor for death and disability. However, alcohol consumpti...
Source: The Lancet - September 18, 2015 Category: Journals (General) Source Type: research

Prophylactic antibiotics after acute stroke for reducing pneumonia in patients with dysphagia (STROKE-INF): a prospective, cluster-randomised, open-label, masked endpoint, controlled clinical trial
This study assessed the effectiveness of antibiotic prophylaxis for reducing pneumonia in patients with dysphagia after acute stroke. Methods We did a prospective, multicentre, cluster-randomised, open-label controlled trial with masked endpoint assessment of patients older than 18 years with dysphagia after new stroke recruited from 48 stroke units in the UK, accredited and included in the UK National Stroke Audit. We excluded patients with contraindications to antibiotics, pre-existing dysphagia, or known infections, or who were not expected to survive beyond 14 days. We randomly assigned the units (1:1) by computer to ...
Source: The Lancet - September 5, 2015 Category: Journals (General) Source Type: research

Prevention of stroke-associated pneumonia: where next?
Publication date: Available online 3 September 2015 Source:The Lancet Author(s): Andreas Meisel, Craig J Smith
Source: The Lancet - September 5, 2015 Category: Journals (General) Source Type: research

Long working hours: an avoidable cause of stroke?
Publication date: Available online 19 August 2015 Source:The Lancet Author(s): Urban Janlert
Source: The Lancet - August 21, 2015 Category: Journals (General) Source Type: research

Long working hours and risk of coronary heart disease and stroke: a systematic review and meta-analysis of published and unpublished data for 603 838 individuals
Publication date: Available online 19 August 2015 Source:The Lancet Author(s): Mika Kivimäki, Markus Jokela, Solja T Nyberg, Archana Singh-Manoux, Eleonor I Fransson, Lars Alfredsson, Jakob B Bjorner, Marianne Borritz, Hermann Burr, Annalisa Casini, Els Clays, Dirk De Bacquer, Nico Dragano, Raimund Erbel, Goedele A Geuskens, Mark Hamer, Wendela E Hooftman, Irene L Houtman, Karl-Heinz Jöckel, France Kittel, Anders Knutsson, Markku Koskenvuo, Thorsten Lunau, Ida E H Madsen, Martin L Nielsen, Maria Nordin, Tuula Oksanen, Jan H Pejtersen, Jaana Pentti, Reiner Rugulies, Paula Salo, Martin J S...
Source: The Lancet - August 21, 2015 Category: Journals (General) Source Type: research

Parenteral antibiotics are not enough to prevent pneumonia in stroke
Publication date: 15–21 August 2015 Source:The Lancet, Volume 386, Issue 9994 Author(s): Luciano Silvestri, Hendrick K F van Saene, Marco Milanese, Silvia Ros, Durk F Zandstra
Source: The Lancet - August 21, 2015 Category: Journals (General) Source Type: research

Parenteral antibiotics are not enough to prevent pneumonia in stroke – Authors' reply
Publication date: 15–21 August 2015 Source:The Lancet, Volume 386, Issue 9994 Author(s): Diederik van de Beek, Matthijs Brouwer, Paul Nederkoorn
Source: The Lancet - August 21, 2015 Category: Journals (General) Source Type: research

The future of stroke therapy must not be mired by past arguments
Publication date: 15–21 August 2015 Source:The Lancet, Volume 386, Issue 9994 Author(s): Alastair M Buchan, Hasneen G Karbalai, Brad A Sutherland
Source: The Lancet - August 21, 2015 Category: Journals (General) Source Type: research

Adenosine-guided pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation: an international, multicentre, randomised superiority trial
Publication date: Available online 23 July 2015 Source:The Lancet Author(s): Laurent Macle, Paul Khairy, Rukshen Weerasooriya, Paul Novak, Atul Verma, Stephan Willems, Thomas Arentz, Isabel Deisenhofer, George Veenhuyzen, Christophe Scavée, Pierre Jaïs, Helmut Puererfellner, Sylvie Levesque, Jason G Andrade, Lena Rivard, Peter G Guerra, Marc Dubuc, Bernard Thibault, Mario Talajic, Denis Roy, Stanley Nattel Background Catheter ablation is increasingly used to manage atrial fibrillation, but arrhythmia recurrences are common. Adenosine might identify pulmonary veins at risk of reconnection by unmaski...
Source: The Lancet - July 29, 2015 Category: Journals (General) Source Type: research

Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study
This study suggests that measurement of grip strength is a simple, inexpensive risk-stratifying method for all-cause death, cardiovascular death, and cardiovascular disease. Further research is needed to identify determinants of muscular strength and to test whether improvement in strength reduces mortality and cardiovascular disease. Funding Full funding sources listed at end of paper (see Acknowledgments).
Source: The Lancet - May 15, 2015 Category: Journals (General) Source Type: research

AVERT: a major milestone in stroke research
Publication date: Available online 10 May 2015 Source:The Lancet Author(s): Peter M Rothwell
Source: The Lancet - May 11, 2015 Category: Journals (General) Source Type: research

50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study
Publication date: Available online 7 May 2015 Source:The Lancet Author(s): Renate B Schnabel , Xiaoyan Yin , Philimon Gona , Martin G Larson , Alexa S Beiser , David D McManus , Christopher Newton-Cheh , Steven A Lubitz , Jared W Magnani , Patrick T Ellinor , Sudha Seshadri , Philip A Wolf , Ramachandran S Vasan , Emelia J Benjamin , Daniel Levy Background Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years. Methods We investigated trends in incidence, prevalence, and risk factors for atrial fibrillat...
Source: The Lancet - May 9, 2015 Category: Journals (General) Source Type: research

Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial
Publication date: Available online 16 April 2015 Source:The Lancet Background Early mobilisation after stroke is thought to contribute to the effects of stroke-unit care; however, the intervention is poorly defined and not underpinned by strong evidence. We aimed to compare the effectiveness of frequent, higher dose, very early mobilisation with usual care after stroke. Methods We did this parallel-group, single-blind, randomised controlled trial at 56 acute stroke units in five countries. Patients (aged ≥18 years) with ischaemic or haemorrhagic stroke, first or recurrent, who met physiological criteria were randomly as...
Source: The Lancet - April 18, 2015 Category: Journals (General) Source Type: research

Thrombolysis in acute stroke
Publication date: 11–17 April 2015 Source:The Lancet, Volume 385, Issue 9976 Author(s): Peter Appelros , Andreas Terént
Source: The Lancet - April 10, 2015 Category: Journals (General) Source Type: research

Thrombolysis for stroke: clinical judgment at its apogee
Publication date: 11–17 April 2015 Source:The Lancet, Volume 385, Issue 9976 Author(s): The Lancet
Source: The Lancet - April 10, 2015 Category: Journals (General) Source Type: research