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Comparison of Carotid Plaque Score and Coronary Artery Calcium Score for Predicting Cardiovascular Disease Events: The Multi-Ethnic Study of Atherosclerosis Epidemiology
BackgroundCoronary artery calcium (CAC) predicts coronary heart disease (CHD) events better than carotid wall plaque presence; however, differences in the utility of CAC burden and carotid plaque burden across the spectrum of cardiovascular disease (CVD) events is unknown.Methods and ResultsCVD, CHD and stroke/transient ischemic attack (TIA) events were evaluated prospectively in a multiethnic cohort without CVD at baseline. Carotid plaque score was determined by the number of ultrasound‐detected plaques in the common, bifurcation, and internal carotid artery segments. CAC was detected by computed tomography. Predictive ...
Source: JAHA:Journal of the American Heart Association - February 14, 2017 Category: Cardiology Authors: Gepner, A. D., Young, R., Delaney, J. A., Budoff, M. J., Polak, J. F., Blaha, M. J., Post, W. S., Michos, E. D., Kaufman, J., Stein, J. H. Tags: Epidemiology, Primary Prevention, Risk Factors, Computerized Tomography (CT), Magnetic Resonance Imaging (MRI) Original Research Source Type: research

Prognostic Implications of Left Ventricular Dyssynchrony for Major Adverse Cardiovascular Events in Asymptomatic Women and Men: The Multi-Ethnic Study of Atherosclerosis Heart Failure
Conclusions In an asymptomatic cohort, greater LV dyssynchrony determined by cardiac magnetic resonance imaging predicts adverse cardiovascular outcome in women but not in men. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00005487.
Source: JAHA:Journal of the American Heart Association - August 4, 2014 Category: Cardiology Authors: Sharma, R. K., Volpe, G., Rosen, B. D., Ambale-Venkatesh, B., Donekal, S., Fernandes, V., Wu, C. O., Carr, J., Bluemke, D. A., Lima, J. A. C. Tags: Heart Failure Source Type: research

N-glycome Profile Levels Relate to Silent Brain Infarcts in a Cohort of Hypertensives Imaging
Conclusions N-glycome levels might be potentially useful as biomarkers for the presence of silent cerebrovascular disease.
Source: JAHA:Journal of the American Heart Association - November 23, 2015 Category: Cardiology Authors: Vilar-Bergua, A., Riba-Llena, I., Vanhooren, V., Dewaele, S., Libert, C., Penalba, A., Montaner, J., Delgado, P. Tags: Imaging Source Type: research

Neuropsychological Status and Structural Brain Imaging in Adolescents With Single Ventricle Who Underwent the Fontan Procedure Congenital Heart Disease
Conclusions The neuropsychological deficits and high frequencies of structural brain abnormalities in adolescents who underwent the Fontan procedure highlight the need for research on interventions to improve the long-term outcomes in this high-risk group.
Source: JAHA:Journal of the American Heart Association - December 14, 2015 Category: Cardiology Authors: Bellinger, D. C., Watson, C. G., Rivkin, M. J., Robertson, R. L., Roberts, A. E., Stopp, C., Dunbar-Masterson, C., Bernson, D., DeMaso, D. R., Wypij, D., Newburger, J. W. Tags: Congenital Heart Disease Source Type: research

Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study Epidemiology
Conclusions Cumulative vascular risk factor exposure may increase the risk of CMB, especially in deep regions. The apparent paradoxical association of carotid intima–media thickness progression with lower risk of CMB may reflect benefits of intensive vascular risk factor treatment among persons with higher cardiovascular risk and deserves further investigation. If replicated, the results may have potential implications for assessment of preventive and therapeutic interventions for subclinical cerebral hemorrhage.
Source: JAHA:Journal of the American Heart Association - March 17, 2016 Category: Cardiology Authors: Romero, J. R., Preis, S. R., Beiser, A., DeCarli, C., D'Agostino, R. B., Wolf, P. A., Vasan, R. S., Polak, J. F., Seshadri, S. Tags: Epidemiology, Magnetic Resonance Imaging (MRI), Ultrasound, Cerebrovascular Disease/Stroke, Atherosclerosis Source Type: research

Hemodynamic Tandem Intracranial Lesions on Magnetic Resonance Angiography in Patients Undergoing Carotid Endarterectomy Cardiovascular Surgery
ConclusionsIn patients undergoing carotid endarterectomy, a significant number of preoperative TILs demonstrated hemodynamic components, which were reversed postoperatively. The presence of such components was distinctively associated with the postoperative incidence of new ischemic lesions.
Source: JAHA:Journal of the American Heart Association - October 3, 2016 Category: Cardiology Authors: Lee, E.-J., Cho, Y.-P., Lee, S.-H., Lee, J. S., Nam, H. J., Kim, B. J., Kwon, T.-W., Kang, D.-W., Kim, J. S., Kwon, S. U. Tags: Magnetic Resonance Imaging (MRI), Cardiovascular Surgery, Cerebrovascular Disease/Stroke Original Research Source Type: research

Beta-Blocker Use Is Associated With Impaired Left Atrial Function in Hypertension Hypertension
BackgroundImpaired left atrial (LA) mechanical function is present in hypertension and likely contributes to various complications, including atrial arrhythmias, stroke, and heart failure. Various antihypertensive drug classes exert differential effects on central hemodynamics and left ventricular function. However, little is known about their effects on LA function.Methods and ResultsWe studied 212 subjects with hypertension and without heart failure or atrial fibrillation. LA strain was measured from cine steady‐state free‐precession cardiac MRI images using feature‐tracking algorithms. In multivariable models adju...
Source: JAHA:Journal of the American Heart Association - February 3, 2017 Category: Cardiology Authors: Sardana, M., Syed, A. A., Hashmath, Z., Phan, T. S., Koppula, M. R., Kewan, U., Ahmed, Z., Chandamuri, R., Varakantam, S., Shah, E., Gorz, R., Akers, S. R., Chirinos, J. A. Tags: Atrial Fibrillation, Hypertension, Magnetic Resonance Imaging (MRI) Original Research Source Type: research

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