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Long-Term Risk of Cardiovascular Events in Patients With Chronic Kidney Disease Who Have Survived Sepsis: A Nationwide Cohort Study Epidemiology
ConclusionsOur findings highlight the association of sepsis with a significantly increased long‐term risk of cardiovascular events among survivors in the chronic kidney disease population.
Source: JAHA:Journal of the American Heart Association - February 10, 2017 Category: Cardiology Authors: Shih, C.-J., Chao, P.-W., Ou, S.-M., Chen, Y.-T. Tags: Cardiovascular Disease, Epidemiology, Risk Factors Original Research Source Type: research

Dynamic TIMI Risk Score for STEMI Coronary Heart Disease
Conclusions This score is a prospectively derived, validated means of estimating 1-year mortality of STEMI at hospital discharge and can serve as a clinically useful tool. By incorporating events during the index hospitalization, it can better define risk and help to guide treatment decisions.
Source: JAHA:Journal of the American Heart Association - January 29, 2013 Category: Cardiology Authors: Amin, S. T., Morrow, D. A., Braunwald, E., Sloan, S., Contant, C., Murphy, S., Antman, E. M. Tags: Coronary Heart Disease Source Type: research

Sex-Specific Differences in the Predictive Value of Cholesterol Homeostasis Markers and 10-Year Cardiovascular Disease Event Rate in Framingham Offspring Study Participants Coronary Heart Disease
Conclusions These data suggest significant sex differences in the 10-year prognostic value of cholesterol synthesis markers and HCHD, specifically coronary death and incidence of myocardial infarction. Clinical Trial Registration URL:http://ClinicalTrials.gov. Unique identifier: NCT00074464.
Source: JAHA:Journal of the American Heart Association - February 19, 2013 Category: Cardiology Authors: Matthan, N. R., Zhu, L., Pencina, M., D'Agostino, R. B., Schaefer, E. J., Lichtenstein, A. H. Tags: Coronary Heart Disease Source Type: research

Hostility, Health Behaviors, and Risk of Recurrent Events in Patients With Stable Coronary Heart Disease: Findings From the Heart and Soul Study Epidemiology
Conclusions Hostility was a significant predictor of secondary events in this sample of outpatients with baseline stable CHD. Much of this association was moderated by poor health behaviors, specifically physical inactivity and smoking.
Source: JAHA:Journal of the American Heart Association - September 30, 2013 Category: Cardiology Authors: Wong, J. M., Na, B., Regan, M. C., Whooley, M. A. Tags: Epidemiology Source Type: research

Peripheral Endothelial Function and Cardiovascular Events in High-Risk Patients Vascular Medicine
Conclusions Advanced endothelial dysfunction significantly correlated with near future cardiovascular events in high-risk patients. This physiological vascular measurement improved risk discrimination when added to the FRS, BNP, and SYNTAXsc. Clinical Trial Registration URL: clinicaltrials.gov (http://www.clinicaltrials.gov). Unique identifier: NCT00737945.
Source: JAHA:Journal of the American Heart Association - November 25, 2013 Category: Cardiology Authors: Matsuzawa, Y., Sugiyama, S., Sumida, H., Sugamura, K., Nozaki, T., Ohba, K., Matsubara, J., Kurokawa, H., Fujisue, K., Konishi, M., Akiyama, E., Suzuki, H., Nagayoshi, Y., Yamamuro, M., Sakamoto, K., Iwashita, S., Jinnouchi, H., Taguri, M., Morita, S., Ma Tags: Vascular Medicine Source Type: research

Cardiovascular and Mortality Risk of Apparent Resistant Hypertension in Women With Suspected Myocardial Ischemia: A Report From the NHLBI-Sponsored WISE Study Hypertension
Conclusions In this cohort of women with evidence of ischemia, aTRH was associated with a profoundly increased long-term risk of major adverse events, including death, that emerged early during follow-up.
Source: JAHA:Journal of the American Heart Association - February 28, 2014 Category: Cardiology Authors: Smith, S. M., Huo, T., Delia Johnson, B., Bittner, V., Kelsey, S. F., Vido Thompson, D., Noel Bairey Merz, C., Pepine, C. J., Cooper-DeHoff, R. M. Tags: Hypertension Source Type: research

Adherence to Guideline-Recommended Therapy Is Associated With Decreased Major Adverse Cardiovascular Events and Major Adverse Limb Events Among Patients With Peripheral Arterial Disease Heart Failure
Conclusions In patients with claudication or CLI, combination treatment with four guideline-recommended therapies is associated with significant reductions in MACE, MALE, and mortality.
Source: JAHA:Journal of the American Heart Association - April 10, 2014 Category: Cardiology Authors: Armstrong, E. J., Chen, D. C., Westin, G. G., Singh, S., McCoach, C. E., Bang, H., Yeo, K.-K., Anderson, D., Amsterdam, E. A., Laird, J. R. Tags: Heart Failure Source Type: research

Long-term Cardiovascular Outcomes in Patients With Chronic Kidney Disease Undergoing Coronary Artery Bypass Graft Surgery for Acute Coronary Syndromes Cardiovascular Surgery
Conclusions Severe, but not moderate, renal dysfunction was independently associated with an increased risk of long-term cardiovascular events and death in patients undergoing CABG for acute coronary syndromes.
Source: JAHA:Journal of the American Heart Association - March 4, 2014 Category: Cardiology Authors: Holzmann, M., Jernberg, T., Szummer, K., Sartipy, U. Tags: Cardiovascular Surgery Source Type: research

Early Clopidogrel Versus Prasugrel Use Among Contemporary STEMI and NSTEMI Patients in the US: Insights From the National Cardiovascular Data Registry Coronary Heart Disease
Conclusions With prasugrel as an antiplatelet treatment option, contemporary practice shows low uptake of prasugrel and delays in P2Y12 antagonist initiation among NSTEMI patients. We also note concerning evidence of inappropriate use of prasugrel, and inadequate targeting of this more potent therapy to maximize the benefit/risk ratio.
Source: JAHA:Journal of the American Heart Association - April 14, 2014 Category: Cardiology Authors: Sherwood, M. W., Wiviott, S. D., Peng, S. A., Roe, M. T., DeLemos, J., Peterson, E. D., Wang, T. Y. Tags: Coronary Heart Disease Source Type: research

B-type Natriuretic Peptides for the Prediction of Cardiovascular Events in Patients With Stable Coronary Heart Disease: The Heart and Soul Study Coronary Heart Disease
Conclusions Both BNP and NT-proBNP were significant predictors of MACE in stable coronary heart disease; however, NT-proBNP was superior to BNP for net risk reclassification for MACE.
Source: JAHA:Journal of the American Heart Association - July 22, 2014 Category: Cardiology Authors: Mishra, R. K., Beatty, A. L., Jaganath, R., Regan, M., Wu, A. H. B., Whooley, M. A. Tags: Coronary Heart Disease Source Type: research

Incremental Prognostic Significance of the Elevated Levels of Pentraxin 3 in Patients With Heart Failure With Normal Left Ventricular Ejection Fraction Heart Failure
Conclusions High plasma PTX3 levels, but not other inflammatory markers, are correlated with future cardiovascular events in patients with HFNEF. PTX3 may be a useful biomarker for assessment of risk stratification in HFNEF. Clinical Trial Registration URL: http://www.umin.ac.jp; Unique identifier: UMIN000002170.
Source: JAHA:Journal of the American Heart Association - July 10, 2014 Category: Cardiology Authors: Matsubara, J., Sugiyama, S., Nozaki, T., Akiyama, E., Matsuzawa, Y., Kurokawa, H., Maeda, H., Fujisue, K., Sugamura, K., Yamamoto, E., Matsui, K., Jinnouchi, H., Ogawa, H. Tags: Heart Failure Source Type: research

Prognostic Implications of Left Ventricular Dyssynchrony for Major Adverse Cardiovascular Events in Asymptomatic Women and Men: The Multi-Ethnic Study of Atherosclerosis Heart Failure
Conclusions In an asymptomatic cohort, greater LV dyssynchrony determined by cardiac magnetic resonance imaging predicts adverse cardiovascular outcome in women but not in men. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00005487.
Source: JAHA:Journal of the American Heart Association - August 4, 2014 Category: Cardiology Authors: Sharma, R. K., Volpe, G., Rosen, B. D., Ambale-Venkatesh, B., Donekal, S., Fernandes, V., Wu, C. O., Carr, J., Bluemke, D. A., Lima, J. A. C. Tags: Heart Failure Source Type: research

Prognostic Value of Estimated Functional Capacity Incremental to Cardiac Biomarkers in Stable Cardiac Patients Coronary Heart Disease
Conclusion A simple self-assessment tool of functional capacity in stable patients undergoing elective diagnostic cardiac evaluation provides independent and incremental prognostic value for prediction of both significant coronary angiographic disease and long-term adverse clinical events.
Source: JAHA:Journal of the American Heart Association - October 20, 2014 Category: Cardiology Authors: Tang, W. H. W., Topol, E. J., Fan, Y., Wu, Y., Cho, L., Stevenson, C., Ellis, S. G., Hazen, S. L. Tags: Coronary Heart Disease Source Type: research

Short-Term Change in eGFR and Risk of Cardiovascular Events Health Services and Outcomes Research
Conclusion Clinically relevant changes in eGFR are associated with increased risk of cardiovascular events. However, most of the apparent increase in risk can be accounted for by assessing comorbidity and baseline kidney function.
Source: JAHA:Journal of the American Heart Association - September 11, 2014 Category: Cardiology Authors: Turin, T. C., James, M. T., Jun, M., Tonelli, M., Coresh, J., Manns, B. J., Hemmelgarn, B. R. Tags: Health Services and Outcomes Research Source Type: research

A Novel Protein Glycan Biomarker and Future Cardiovascular Disease Events Epidemiology
Conclusions In this prospective study of initially healthy women, baseline GlycA was associated with incident CVD, consistent with a possible role for protein glycans in inflammation and CVD. Clinical Trial Registration URL: http//clinicaltrials.gov/. Unique identifier NCT00000479.
Source: JAHA:Journal of the American Heart Association - September 23, 2014 Category: Cardiology Authors: Akinkuolie, A. O., Buring, J. E., Ridker, P. M., Mora, S. Tags: Epidemiology Source Type: research

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