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Atrial Fibrillation Diagnosis Timing, Ambulatory ECG Monitoring Utilization, and Risk of Recurrent Stroke Original Articles
Conclusions— AF diagnosed after stroke is an important hallmark of recurrent stroke risk. Increasing the low utilization of cardiac monitoring after stroke could identify undiagnosed AF earlier, leading to appropriate oral anticoagulation treatment and a reduction in stroke/TIA recurrence.
Source: Circulation: Cardiovascular Quality and Outcomes - January 16, 2017 Category: Cardiology Authors: Lip, G. Y. H., Hunter, T. D., Quiroz, M. E., Ziegler, P. D., Turakhia, M. P. Tags: Arrhythmias, Electrophysiology, Atrial Fibrillation, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Articles Source Type: research

Risks and Benefits of Anticoagulation in Atrial Fibrillation: Insights From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry Original Articles
Conclusions— In community-based outpatients with AF, use of OAC was high and driven by not only predominantly stroke but also bleeding risk. Stroke risk significantly affects OAC use among those with low bleeding risk, whereas those with high bleeding risk demonstrate consistently lower use of OAC regardless of stroke risk.
Source: Circulation: Cardiovascular Quality and Outcomes - July 16, 2013 Category: Cardiology Authors: Cullen, M. W., Kim, S., Piccini, J. P., Ansell, J. E., Fonarow, G. C., Hylek, E. M., Singer, D. E., Mahaffey, K. W., Kowey, P. R., Thomas, L., Go, A. S., Lopes, R. D., Chang, P., Peterson, E. D., Gersh, B. J., on behalf of the ORBIT-AF Investigators Tags: Coumarins, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Risk Factors for Stroke, Anticoagulants Original Articles Source Type: research

Abstract 201: Are Patients With Atrial Fibrillation Willing to Consider New Strategies to Prevent Stroke? A Qualitative Analysis of Community-Based Focus Groups Session Title: Abstract Poster Session II
Conclusion: Focus group participants expressed a fear of debilitating stroke, with varying levels of acceptance of inconveniences and potential bleeding associated with blood thinners. Among a subset of participants, there was willingness to consider new stroke prevention therapies; however, this was preferred with a known, trusted physician. Subspecialized clinicians offering new therapies may be challenged to establish perceived mutual respect with patients, traditionally built over time, and this may be required for patients to consider new therapies. Future research is needed to determine best practices for both establ...
Source: Circulation: Cardiovascular Quality and Outcomes - February 26, 2016 Category: Cardiology Authors: ONeill, E. S., Grande, S. W., Coylewright, M. Tags: Session Title: Abstract Poster Session II Source Type: research

Does Sex Affect Anticoagulant Use for Stroke Prevention in Nonvalvular Atrial Fibrillation?: The Prospective Global Anticoagulant Registry in the FIELD-Atrial Fibrillation Original Articles
Conclusions— These contemporary global data show that anticoagulant use for stroke prevention is no different in men and women with nonvalvular AF. Thromboprophylaxis was, however, suboptimal in substantial proportions of men and women, with underuse in those at moderate-to-high risk of stroke and overuse in those at low risk. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362.
Source: Circulation: Cardiovascular Quality and Outcomes - March 5, 2015 Category: Cardiology Authors: Lip, G. Y. H., Rushton-Smith, S. K., Goldhaber, S. Z., Fitzmaurice, D. A., Mantovani, L. G., Goto, S., Haas, S., Bassand, J.-P., Camm, A. J., Ambrosio, G., Jansky, P., Al Mahmeed, W., Oh, S., van Eickels, M., Raatikainen, P., Steffel, J., Oto, A., Kayani, Tags: Health policy and outcome research, Coumarins, Other anticoagulants, Arrhythmias, clinical electrophysiology, drugs Original Articles Source Type: research

Abstract 267: A Single-page Best Practice Algorithm Reduces Stroke Risk and Improves Arrhythmia Management Decisions in Patients With Acute Atrial Fibrillation: A Quality Improvement Project Session Title: Poster Session PM
Conclusions: Using established quality improvement methodology and cost-neutral multi-disciplinary expertise, this novel management algorithm has significantly improved the quality and safety of care for patients with acute AF at NMUH. Prospective analysis of long-term adverse outcomes is now required to establish morbidity or mortality benefit.
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Maclean, E., Patel, S., Joseph, O., de Block Golding, D., Maden, S., Boot, J., Denning, M., Rear, R. Tags: Session Title: Poster Session PM Source Type: research

End of Study Transition From Study Drug to Open-Label Vitamin K Antagonist Therapy: The ROCKET AF Experience Original Articles
Conclusions— The excess of events at EOS was likely because of a period of inadequate anticoagulation in rivaroxaban participants switched to vitamin K antagonist therapy. If transition from rivaroxaban to vitamin K antagonist is needed, timely monitoring and careful dosing should be used to ensure consistent and adequate anticoagulation.
Source: Circulation: Cardiovascular Quality and Outcomes - July 16, 2013 Category: Cardiology Authors: Mahaffey, K. W., Hellkamp, A. S., Patel, M. R., Hannan, K. L., Schwabe, K., Nessel, C. C., Berkowitz, S. D., Halperin, J. L., Hankey, G. J., Becker, R. C., Piccini, J. P., Breithardt, G., Hacke, W., Singer, D. E., Califf, R. M., Fox, K. A. A. Tags: Platelet function inhibitors, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Anticoagulants Original Articles Source Type: research

Riskier Business: Atrial Fibrillation Stroke Prevention in the CHA2DS2-VASc Era Editorials
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2017 Category: Cardiology Authors: Dewland, T. A., Stecker, E. C. Tags: Arrhythmias, Quality and Outcomes, Ischemic Stroke Editorials Source Type: research

Higher Persistence in Newly Diagnosed Nonvalvular Atrial Fibrillation Patients Treated With Dabigatran Versus Warfarin Original Articles
Conclusions— Patients who initiated dabigatran treatment were more persistent than patients who began warfarin treatment. Within each cohort, patients with lower stroke risk were more likely to discontinue therapy.
Source: Circulation: Cardiovascular Quality and Outcomes - September 17, 2013 Category: Cardiology Authors: Zalesak, M., Siu, K., Francis, K., Yu, C., Alvrtsyan, H., Rao, Y., Walker, D., Sander, S., Miyasato, G., Matchar, D., Sanchez, H. Tags: Compliance/Adherence, Other anticoagulants, Arrhythmias, clinical electrophysiology, drugs, Anticoagulants Original Articles Source Type: research

Integrating Real-Time Clinical Information to Provide Estimates of Net Clinical Benefit of Antithrombotic Therapy for Patients With Atrial Fibrillation Original Articles
Conclusions— Use of a decision support tool that integrates patient-specific stroke and bleeding risk could result in significant gains in quality-adjusted life expectancy for a primary care population of patients with atrial fibrillation.
Source: Circulation: Cardiovascular Quality and Outcomes - September 16, 2014 Category: Cardiology Authors: Eckman, M. H., Wise, R. E., Speer, B., Sullivan, M., Walker, N., Lip, G. Y. H., Kissela, B., Flaherty, M. L., Kleindorfer, D., Khan, F., Kues, J., Baker, P., Ireton, R., Hoskins, D., Harnett, B. M., Aguilar, C., Leonard, A., Prakash, R., Arduser, L., Cost Tags: Health policy and outcome research, Primary prevention, Coumarins, Thrombosis risk factors, Arrhythmias, clinical electrophysiology, drugs, Anticoagulants, Epidemiology Original Articles Source Type: research

Abstract 315: Feasibility of outpatient ambulatory ECG monitoring to screen for silent atrial fibrillation: Pilot Findings from Screening Trial for Undiagnosed Atrial Fibrillation (STUDY-AF) Poster Session III
CONCLUSION: Ambulatory screening of asymptomatic arrhythmias using the Zio® Patch is feasible; however the diagnostic yield for silent AF may be low, even among patients with established AF risk factors. Our study found a high prevalence of incidental asymptomatic SVT and NSVT. A larger trial with more targeted enrollment may be required to demonstrate the value of screening for AF. The impact of detecting incidental NSVT or SVT, which themselves could prompt evaluation and may be relevant to development of AF, requires further investigation.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Ullal, A. J., Hoang, D. D., Than, C., Heidenreich, P. A., Miller, J. D., Friday, K., Froelicher, V. F., Turakhia, M. P. Tags: Poster Session III Source Type: research

Abstract 246: Cost-analysis and Clinical Outcomes in Medicare Patients Who Have Received Holter Monitoring Session Title: Poster Session II
Conclusions: Repeat monitoring, often of the same type as done initially, frequently did not yield a diagnosis and patients continued to experience clinical events at a substantial healthcare cost. Additional diagnostic paradigms should be explored to improve these patient and system outcomes.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Lenane, J. C., Layton, A. J., Becker, S. H., Alexander, J. H. Tags: Session Title: Poster Session II Source Type: research

Abstract 174: Clinical Prediction Models for Cardiovascular Disease: The Tufts PACE CPM Database Session Title: Poster Session I
Conclusions: There is an abundance of CPMs available for many CVD conditions, with substantial redundancy in the literature. The comparative performance of these models, the consistency of effects and risk estimates across models and the actual and potential clinical impact of this body of literature is poorly understood.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Wessler, B. S., Lai YH, L., Kramer, W., Cangelosi, M., Raman, G., Lutz, J., Kent, D. M. Tags: Session Title: Poster Session I Source Type: research

Anticoagulation for Nonvalvular Atrial Fibrillation: Influence of Epidemiologic Trends and Clinical Practice Patterns on Risk Stratification and Net Clinical Benefit Cardiovascular Perspective
Source: Circulation: Cardiovascular Quality and Outcomes - September 11, 2017 Category: Cardiology Authors: Asinger, R. W., Shroff, G. R., Simegn, M. A., Herzog, C. A. Tags: Arrhythmias, Cerebrovascular Disease/Stroke, Ischemic Stroke Cardiovascular Perspective Source Type: research

Priorities for Comparative Effectiveness Reviews in Cardiovascular Disease Original Articles
Conclusions— Using a systematic process deriving consensus from multiple stakeholders across cardiovascular disease states, we generated a prioritized list of evidence synthesis topics to inform decision makers. The topics vetted through this process seek to determine the comparative safety and effectiveness of a range of treatments, both established and emerging, and are immediately relevant for prevalent disease states.
Source: Circulation: Cardiovascular Quality and Outcomes - March 19, 2013 Category: Cardiology Authors: Eapen, Z. J., McBroom, A. J., Gray, R., Musty, M. D., Hadley, C., Hernandez, A. F., Sanders, G. D. Tags: Health policy and outcome research, Congestive, Cerebrovascular disease/stroke, Acute coronary syndromes, Arrhythmias, clinical electrophysiology, drugs Original Articles Source Type: research

Abstract 122: Adult Congenital Heart Surgery Safely Performed at Pediatric Hospitals: 115 Consecutive Open Heart Surgeries Without a Mortality or Significant Morbidity Poster Session I
Conclusions: There is a growing need to develop care strategies for adults with congenital heart disease. By developing a focus of care at pediatric hospital, adults received outstanding surgical results with very little morbidity or mortality.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Phillips, A., Olshove, V. Tags: Poster Session I Source Type: research

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