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Source: Heart Rhythm
Condition: Arrhythmia
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Total 46 results found since Jan 2013.
B-po03-148 risk stratification for ischemic stroke and major bleeding in patients without atrial fibrillation - validity of cha2ds2-vasc and has-bled score
Atrial fibrillation (AF) is the most common arrhythmia. Recent cardiac implantable electronic devices (CIEDs) have led to an improvement in the early detection of AF episodes. ESC guidelines for the management of AF recommend the use of CHA2DS2-VASc score as class I to predict the risk of ischemic stroke in patients with AF. However, the validity of the CHA2DS2-VASc and HAS-BLED scores to predict ischemic stroke and major bleeding events in patients without AF remains unclear.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Miyo Nakano, Yusuke Kondo, Masahiro Nakano, Takatsugu Kajiyama, Ryo Ito, Haruhiro Takahira, Mari Kitagawa, Masafumi Sugawara, Toshinori Chiba, Yoshio Kobayashi Source Type: research
Po-01-210 stroke risk is identified by slow blood flow and stagnant blood particles in the left atrium
Atrial fibrillation (AF) is the most common type of arrhythmia, causing irregular contraction patterns in the atrial chambers. This rhythm disorder may result in stagnant flow, leading to the formation of blood clots, especially in the left atrial appendage (LAA), and causing a thrombotic stroke. Current stroke risk assessment in AF patients is done using CHADS2 or CHA2 DS2 –VASc scores, which are based on selected clinical characteristics, without accounting for potential risk factors such as LAA thrombi formation.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Alberto Zingaro, Zan Ahmad, Carolyna Yamamoto Alves Pinto, Kensuke Sakata, Eugene G. Kholmovski, Luca Dede', Alfio Quarteroni, Natalia A. Trayanova Source Type: research
Ce-454029-4 racial disparities in the use of oral anticoagulation for atrial fibrillation by sex and within high and low stroke risk populations
Atrial fibrillation (AF) is the most common arrhythmia and is associated with an increased risk of ischemic stroke. Oral anticoagulation (OAC) has been shown to reduce the risk of ischemic stroke in patients with AF. Previous studies have demonstrated that both females and Black, Hispanic, and Asian groups are less likely to be prescribed OAC.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: William Tate, Grace Ha, Leon M. Ptaszek, Dolphurs Hayes, James M. Alzate, Joseph R. Betancourt, Jason H. Wasfy, Malissa J. Wood, Moussa Mansour Source Type: research
Admittance to detect alterations in left ventricular stroke volume
Implantable cardioverter-defibrillators monitor intracardiac electrocardiograms (EGMs) to discriminate between ventricular and supraventricular tachycardias. The incidence of inappropriate shocks remains high because of misclassification of the tachycardia in an otherwise hemodynamically stable individual. Coupling EGMs with an assessment of left ventricular (LV) stroke volume (SV) could help in gauging hemodynamics during an arrhythmia and reducing inappropriate shocks.
Source: Heart Rhythm - June 27, 2014 Category: Cardiology Authors: Erik R. Larson, John E. Porterfield, Sandeep Sagar, Juan Marmol-Velez, Manoj Panday, Daniel Escobedo, Joel Michalek, Yongjian Ouyang, Jonathan W. Valvano, John A. Pearce, Marc D. Feldman Source Type: research
Refining the Prediction of Stroke in Atrial Fibrillation. An elusive endeavor
Atrial fibrillation (AF), the most common sustained arrhythmia, is responsible for>20% of all strokes.1 AF-associated strokes are more severe, causing significantly greater long-term disability, accounting for greater resource utilization, and result in significantly higher mortality when compared to non-AF strokes.2-4 Oral anticoagulants (OACs) are the standard of care for the prevention of AF-associated stroke and systemic thromboembolism. To date OACs are the only therapeutic intervention that has been consistently and definitively shown to improve survival in the AF population.
Source: Heart Rhythm - December 18, 2018 Category: Cardiology Authors: Jason G. Andrade, Laurent Macle Source Type: research
Refining the prediction of stroke in atrial fibrillation: An elusive endeavor
Atrial fibrillation (AF), the most common sustained arrhythmia, is responsible for>20% of all strokes.1 AF-associated strokes are more severe, causing significantly greater long-term disability, accounting for greater resource utilization, and resulting in significantly higher mortality compared to non-AF strokes.2 –4 Oral anticoagulants (OACs) are the standard of care for the prevention of AF-associated stroke and systemic thromboembolism. To date, OACs are the only therapeutic intervention that has been consistently and definitively shown to improve survival in the AF population.
Source: Heart Rhythm - December 18, 2018 Category: Cardiology Authors: Jason G. Andrade, Laurent Macle Tags: Editorial Commentary Source Type: research
B-po05-199 differences in stroke or systemic thromboembolism readmissions after hospitalization for atrial fibrillation or atrial flutter
Although atrial fibrillation (AF) and atrial flutter (AFL) are different arrhythmias, they are assumed to confer the same risk of stroke and systemic thromboembolism (STE) despite a lack of available evidence.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Harshith Thyagaturu, Alexander Bolton, Sittinun Thangjui, Dinesh Voruganti, Hakan Paydak Source Type: research
Left atrial appendage closure: A new technique for clinical practice
Conclusion: This review concludes that it is now appropriate to consider these techniques for patients with AF who are at high risk for stroke for whom effective conventional or novel anticoagulant therapy is not available or who present problems in managing drug treatment.
Source: Heart Rhythm - December 2, 2013 Category: Cardiology Authors: A John Camm, Antonio Colombo, Giorgio Corbucci, Luigi Padeletti Tags: Contemporary Review--Section Editor: Sami Viskin Source Type: research
Patients treated with catheter ablation for ventricular tachycardia after an ICD shock have lower long-term rates of death and heart failure hospitalization than do patients treated with medical management only
Background: Ventricular arrhythmias in patients with implantable cardioverter-defibrillators (ICDs) adversely affect outcomes. Antiarrhythmic approaches to ventricular tachycardia (VT) have variable efficacy and may increase risk of ventricular arrhythmias, worsening cardiomyopathy, and death. Comparatively, VT ablation is an alternative approach that may favorably affect outcomes.Objective: To further explore the effect on long-term outcomes after catheter ablation of VT, we compared patients with history of ICD shocks who did not undergo ablation, patients with a history of ICD shocks that underwent ablation, and patient...
Source: Heart Rhythm - December 12, 2013 Category: Cardiology Authors: T. Jared Bunch, J. Peter Weiss, Brian G. Crandall, John D. Day, Heidi T. May, Tami L. Bair, Jeffrey S. Osborn, Charles Mallender, Avi Fischer, Kyle J. Brunner, Srijoy Mahapatra Tags: Ventricular Tachycardia Source Type: research
Virchow triad and beyond in atrial fibrillation
Atrial fibrillation (AF), the most common type of arrhythmia in adults, is associated with a 5-fold increase in the incidence of ischemic stroke. Stroke in patients with AF is believed to be mostly cardioembolic caused by left atrial thrombi and is an important cause for hospitalizations and cardiovascular deaths. Although various kinds of direct oral anticoagulants have been developed and used for the prevention hopefully decreasing this fateful event, more knowledge about the left atrial thrombi would be required to improve and refine the pharmacological stroke prevention in AF.
Source: Heart Rhythm - September 7, 2016 Category: Cardiology Authors: Takeshi Yamashita Tags: Editorial Commentary Source Type: research
Device-Guided Anticoagulation in Atrial Fibrillation: Not yet ready for prime time
Atrial fibrillation (AF), the most common sustained arrhythmia encountered in clinical practice, is associated with a three- to five-fold increased risk of stroke (accounting for>20% of all strokes).1 Independent of age and other risk factors, AF-associated strokes are relatively more severe, causing greater resource utilization, long-term disability, and mortality compared to non-AF stroke. Oral anticoagulants (OACs) are paramount in preventing AF-associated stroke and systemic thromboembolism.
Source: Heart Rhythm - July 10, 2018 Category: Cardiology Authors: Christopher C. Cheung, Jason G. Andrade Source Type: research
Increasing time between first diagnosis of atrial fibrillation and catheter ablation adversely affects long-term outcomes
Conclusion: Delays in treatment with catheter ablation impact procedural success rates independent of temporal changes to the AF subtype at ablation.
Source: Heart Rhythm - May 22, 2013 Category: Cardiology Authors: T. Jared Bunch, Heidi T. May, Tami L. Bair, David L. Johnson, J. Peter Weiss, Brian G. Crandall, Jeffrey S. Osborn, Jeffrey L. Anderson, J. Brent Muhlestein, Donald L. Lappe, John D. Day Tags: Clinical Source Type: research
Atrial Ca2+/calmodulin-dependent protein kinase II: A druggable master switch of atrial fibrillation-associated atrial remodeling?
Atrial fibrillation (AF) is the most common arrhythmia and is associated with increased morbidity and mortality, with heart failure (HF) and thromboembolism including stroke being the major consequences.1 Thus, stroke prevention with oral anticoagulants is crucial, but highly challenging, for AF management in many patients.2,3 Although our understanding of the underlying molecular mechanisms promoting AF increased substantially over the years, contemporary approaches using drugs are only moderately effective and have substantial side effects, including proarrhythmia.
Source: Heart Rhythm - February 5, 2019 Category: Cardiology Authors: Dobromir Dobrev Tags: Editorial Commentary Source Type: research
Po-701-01 nine month readmission rates and clinical outcomes of anticoagulation versus watchman device in octogenarians
Atrial Fibrillation (AF), the most common arrhythmia in older adults, is fraught with an increased risk of stroke. Studies which have demonstrated non-inferiority of Left atrial appendage occlusion (LAAO) with a watchman device compared to oral anticoagulation for stroke risk reduction in AF did not include patients greater than 80 years of age, making it difficult to generalize these results to this population.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Varun Victor, Mahmoud Khalil, Dilanthy Annappah, Ahmed Mohamed, Kirolos Barssoum Source Type: research
