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The need to know crude event rates in meta-analysis
Numerous reports have recently been aimed at comparing outcomes between on-pump and off-pump coronary artery bypass grafting (CABG). Among these, the meta-analysis by Palmerini et al compared percutaneous coronary intervention with CABG using a network design that included 1 patient group receiving percutaneous coronary intervention (n = 4,653) and 2 patient groups in whom CABG was performed either on-pump (n = 10,957) or off-pump (n = 7,119). The rate of stroke at 30 days was the main end point.
Source: American Heart Journal - July 26, 2013 Category: Cardiology Authors: Andrea Messori, Valeria Fadda, Dario Maratea, Sabrina Trippoli Tags: Letters to the Editor Source Type: research

Atrial fibrillation among Medicare beneficiaries hospitalized with sepsis: Incidence and risk factors
Background: Newly diagnosed atrial fibrillation (AF) during severe sepsis is associated with increased risks of in-hospital stroke and mortality. However, the prevalence, incidence, and risk factors associated with AF during the sepsis syndromes are unclear.Methods: We identified patients with preexisting, newly diagnosed, or no AF in a nationally representative 5% sample of Medicare beneficiaries hospitalized with sepsis between 2004 and 2007. We identified multivariable-adjusted demographic and clinical characteristics associated with development of newly diagnosed AF during a sepsis hospitalization.Results: A total of 6...
Source: American Heart Journal - April 26, 2013 Category: Cardiology Authors: Allan J. Walkey, Melissa A. Greiner, Susan R. Heckbert, Paul N. Jensen, Jonathan P. Piccini, Moritz F. Sinner, Lesley H. Curtis, Emelia J. Benjamin Tags: Electrophysiology Source Type: research

Risk of stroke with percutaneous coronary intervention compared with on-pump and off-pump coronary artery bypass graft surgery: Evidence from a comprehensive network meta-analysis
Conclusions: Percutaneous coronary intervention is associated with lower 30-day rates of stroke than both off-pump and on-pump CABG. Further studies are required to determine whether the risk of stroke is reduced with off-pump CABG compared with on-pump CABG.
Source: American Heart Journal - April 25, 2013 Category: Cardiology Authors: Tullio Palmerini, Giuseppe Biondi-Zoccai, Diego Della Riva, Andrea Mariani, Carlo Savini, Marco Di Eusanio, Philippe Genereux, Giacomo Frati, Antonino G.M. Marullo, Giovanni Landoni, Teresa Greco, Angelo Branzi, Stefano De Servi, Germano Di Credico, Nevio Tags: Curriculum in Cardiology Source Type: research

Treatment of functional mitral valve regurgitation with the permanent percutaneous transvenous mitral annuloplasty system: Results of the multicenter international Percutaneous Transvenous Mitral Annuloplasty System to Reduce Mitral Valve Regurgitation in Patients with Heart Failure trial
Conclusions: Overall, PTMA had mild impact on MR reduction, left ventricular remodeling, QOL, and exercise capacity. During follow-up, the risk/benefit ratio remained suboptimal.
Source: American Heart Journal - February 18, 2013 Category: Cardiology Authors: Jimmy MacHaalany, Luc Bilodeau, Rainer Hoffmann, Stefan Sack, Horst Sievert, Josef Kautzner, Christoph Hehrlein, Patrick Serruys, Mario Sénéchal, Pamela Douglas, Olivier F. Bertrand Tags: Valvular and Congenital Heart Disease Source Type: research

Outcome and safety of same-day-discharge percutaneous coronary interventions with femoral access: A single-center experience
Conclusions: Same-day-discharge after uncomplicated PCI using femoral access is safe when patients are properly selected. The strategy may improve and benefit health costs in the future.
Source: American Heart Journal - January 28, 2013 Category: Cardiology Authors: Lisbeth Antonsen, Lisette Okkels Jensen, Per Thayssen Tags: Interventional Cardiology Source Type: research

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