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Predicting functional outcomes of posterior circulation acute ischemic stroke in first 36  h of stroke onset
In conclusion, both the PC-ASPECTS and NIHSS help clinicians predict functional outcomes. PC-ASPECTS >  7 is a helpful discriminator for achieving favorable functional outcome prediction in posterior circulation acute ischemic stroke.
Source: Journal of Neurology - February 17, 2018 Category: Neurology Source Type: research

Current treatment of central retinal artery occlusion: a national survey
ConclusionsThis survey shows that there is significant variability in treatment practices for acute CRAO in the US. Because of the high cerebrovascular and cardiovascular risk reported in this population of patients, it is notable that the approach to risk factor screening is also highly variable and many programs do not routinely refer patients to an emergency department for urgent evaluation. Finally, there appears to be equipoise among treatment teams regarding the efficacy of systemic fibrinolysis, as 53% of programs report a willingness to treat at least some patients with this modality.
Source: Journal of Neurology - December 13, 2017 Category: Neurology Source Type: research

Thalamic transitory ischemic attacks presenting as Jacksonian sensory march
We report on three cases in which these symptoms were caused by thalamic ischemia. Two patients presented with stereotypically recurring hemiparesthesias lasting 2 –5 min that gradually spread from the face to the arm and leg on one side. A first cerebral magnetic resonance imaging including DWI was negative in both cases, whereas new thalamic infarctions appeared on repeated imaging when clinical symptoms remained. A third case with a thalamic ischemia did not show recurring events, but also presented with purely sensory spreading symptoms. In all three cases EEG and cardiovascular diagnostics revealed normal results. ...
Source: Journal of Neurology - September 11, 2017 Category: Neurology Source Type: research

Higher blood –brain barrier permeability is associated with higher white matter hyperintensities burden
This study aimed to investigate the relationship between BBB permeability and the severity of WMH burden. Consecutive participants without symptomatic stroke history presented for physical examination were recruited in this cross-sectional stud y and divided into three WMH burden groups according to total Fazekas scores. They received dynamic contrast-enhanced-magnetic resonance imaging to measure BBB permeability, and received Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). A total of 102 participants aged 4 9–90 years (mean age of 69.82 years) were enrolled (36 with low WMH burden, 35 w...
Source: Journal of Neurology - June 26, 2017 Category: Neurology Source Type: research

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