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Stroke Risk Factors, Subtypes, and 30-Day Case Fatality in Abuja, Nigeria (P1.121)
CONCLUSIONS: Although hypertension, obesity, diabetes mellitus, and atrial fibrillation were important stroke risk factors, in many patients, these were detected only after a stroke. While the commonest stroke subtype was cerebral infarction, observed in almost two-third of patients, SAH was associated with the highest case-fatality rate at 30 days of 44.4%. Larger population-based studies are planned.Study Supported by: nilDisclosure: Dr. Bwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bwala, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients during Head of Bed Manipulation (P4.216)
CONCLUSIONS: A lower HOB angle results in an increase in cortical CBF without a significant change in arterial flow velocity in the setting of acute stroke, but there is variability across patients in this response. Bedside CBF monitoring with DCS provides a potential means to individualize interventions designed to optimize CBF in acute ischemic stroke.Disclosure: Dr. Favilla has nothing to disclose. Dr. Mesquita has nothing to disclose. Dr. Mullen has nothing to disclose. Dr. Durduran has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Minkoff has nothing to disclose. Dr. Kasner has received personal compensati...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Favilla, C., Mesquita, R., Mullen, M., Durduran, T., Kim, M., Minkoff, D., Kasner, S., Joel, G., Yodh, A., Detre, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular Source Type: research

The relationship between chemerin levels and carotid intima-media thickness in patients with ischemic stroke (P1.262)
Conclusions:Consequently, this study showed that serum chemerin levels may play role in atherosclerosis and ischemic stroke.Study Supported by: Fırat University (FÜBAP)Disclosure: Dr. Demir has nothing to disclose. Dr. Atas has nothing to disclose. Dr. Aytaç has nothing to disclose. Dr. Gonen has nothing to disclose. Dr. Erten has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Demir, C., Ataş, I., Aytac, E., Gonen, M., Erten, Z. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Prevalence of stenoses and occlusions of brain-supplying arteries in young stroke patients
Conclusions: We observed a substantial proportion of atherosclerotic carotid artery stenoses and occlusions in younger stroke patients. Intracranial stenoses and occlusions were even more prevalent than extracranial carotid artery disease. Together with nonstenotic plaques, one-fifth of patients (21.2%) had symptomatic or asymptomatic large-artery atherosclerosis, which should encourage future stroke prevention campaigns to target risk factor modification in young people.
Source: Neurology - April 1, 2013 Category: Neurology Authors: von Sarnowski, B., Schminke, U., Tatlisumak, T., Putaala, J., Grittner, U., Kaps, M., Tobin, W. O., Kinsella, J. A., McCabe, D. J. H., Hennerici, M. G., Fazekas, F., Norrving, B., Kessler, C., Rolfs, A., On behalf of the sifap1 investigators Tags: Stroke in young adults, Ultrasound, Prevalence studies, Risk factors in epidemiology ARTICLE Source Type: research

Premature atherosclerosis: A major contributor to early-onset ischemic stroke
Atherosclerosis is an age-dependent process. The prevalence of large-artery atherosclerosis in case series of ischemic stroke in young adults has been substantially less than in older adults.1–4 Historically, data on the role of atherosclerosis in early-onset stroke have been limited for a variety of reasons. First, multi-institutional studies often have inconsistent evaluations of the cerebral vasculature, particularly the intracranial circulation. Second, studies may not report evidence for proximal atherosclerosis less severe than necessary to meet criteria for etiology. Emerging data, however, show a high inciden...
Source: Neurology - April 1, 2013 Category: Neurology Authors: Kittner, S. J., Singhal, A. B. Tags: Stroke in young adults, Ultrasound, Prevalence studies, Risk factors in epidemiology EDITORIALS Source Type: research

Vitreous Hemorrhage as a Complication of IV-tPA Therapy in a Patient with Acute Stroke (P4.227)
CONCLUSIONS: To our knowledge, this is the first case report of vitreous hemorrhage following acute stroke therapy with IV-tPA. This underscores the risk of intraocular hemorrhage in patients with retinal neovascularization that could occur with other retinal vascular disorders such as diabetic retinopathy. The decision to proceed with IV-tPA in the presence of retinal neovascularization should be made on a case-by-case basis and further discussion with the patient.Disclosure: Dr. Shah has nothing to disclose. Dr. Verstraeten has nothing to disclose. Dr. Wright has nothing to disclose. Dr. Rana has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Shah, L., Verstraeten, T., Wright, D., Rana, S. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Thrombolysis Source Type: research

Recent Nationwide Trends in Transcranial Doppler Utilization During Acute Ischemic Stroke Hospitalizations (P4.296)
Conclusions:Over the last decade there has been a slight but steady decrease in the use of TCD during AIS hospitalizations in the US. Future studies should examine the cost-utility of TCD, especially with the advent of endovascular stroke treatment systems.Disclosure: Dr. Liu has nothing to disclose. Dr. Lunagariya has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Feng has nothing to disclose. Dr. Ovbiagele has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Liu, Y., Lunagariya, A., Patel, U., Patel, A., Feng, W., Ovbiagele, B. Tags: In-Hospital Stroke Care Source Type: research

Teaching NeuroImages: Extracranial internal carotid artery aneurysm causing embolic stroke
A 42-year-old man with no history of trauma experienced acute numbness in his right arm and leg. A pulsating left cervical tumor was noted on clinical examination. Carotid ultrasound demonstrated significant widening of the left proximal internal carotid artery (ICA) and a large nonocclusive hypoechoic structure compatible with an aneurysm and intraluminal thrombus (figure, B, D, and E). MRI confirmed a fusiform extracranial ICA aneurysm and showed a left-sided small embolic stroke (figure, A and C). The patient underwent anticoagulation with low-molecular-weight heparin and eventually surgical treatment (i.e., resection a...
Source: Neurology - July 14, 2014 Category: Neurology Authors: Barlinn, K., Kepplinger, J., Puetz, V., Bodechtel, U. Tags: Stroke in young adults, MRI, Ultrasound, Embolism RESIDENT AND FELLOW SECTION Source Type: research

Cerebral perfusion in stroke-like migraine attacks after radiation therapy syndrome
We present 2 patients with recurrent attacks of SMART syndrome with increased cerebral blood volume in affected regions and abnormal vascular reactivity on transcranial Doppler ultrasound, suggesting a potential mechanism.
Source: Neurology - February 22, 2016 Category: Neurology Authors: Olsen, A. L., Miller, J. J., Bhattacharyya, S., Voinescu, P. E., Klein, J. P. Tags: MRI, All Clinical Neurology, All Cerebrovascular disease/Stroke, Radiation therapy-tumor CLINICAL/SCIENTIFIC NOTES Source Type: research

Prevalence and Clinical Correlation of Left Ventricular Systolic Dysfunction in African American Population with Ischemic Stroke (P02.044)
CONCLUSIONS: In this study the prevalence of LVSD in AA population with ischemic stroke was 22.45%. Among these, there was correlation between location of stroke and severity of LVSD. However prospective randomized studies are needed to validate our results. Disclosure: Dr. Devulapalli has nothing to disclose. Dr. Dunlap has nothing to disclose. Dr. Wilson has nothing to disclose. Dr. Cockburn has nothing to disclose. Dr. Kurukumbi has nothing to disclose. Dr. Jayam-Trouth has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Devulapalli, S., Dunlap, S., Wilson, N., Cockburn, S., Kurukumbi, M., Jayam-Trouth, A. Tags: P02 Cerebrovascular Disease II Source Type: research

Anabolic Steroids Abuse And Ischemic Stroke: A Case Report And Literature Review (P6.247)
CONCLUSIONS:Due to new upcoming socio-behavioral aspects of adolescents and young adults life, neurologists should be screen this unusual risk factor in young patients with stroke.Study Supported by:Disclosure: Dr. Xiong has nothing to disclose. Dr. Velez has nothing to disclose. Dr. Khanna has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Xiong, G., Velez, A., Khanna, A. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Etiologic Epidemiology of Ischemic Stroke (A Study About 2450 Cases) (P1.120)
Conclusions: The main etiology of ischemic stroke in elderly person was lacunar infract followed by atherosclerosis and atrial fibrillation. In Young adults, etiology differs according to country. In our study Carotid dissection takes the first place in patients with age under 45 years old Etiological investigations and a swift implementation of strategy for the prevention of the risk factors are important faced with increased incidence of ischemic stroke. Despite a complete assessment, ischemic stroke etiology can remain indeterminate.Disclosure: Dr. bouzidi has nothing to disclose. Dr. AYADI has nothing to disclose. Dr. ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Bouzidi, N., Ayadi, B., Bouchhima, I., Turki, E., Damak, M., Mhiri, C. Tags: Cerebrovascular Disease: Epidemiology Source Type: research

Ischemic stroke in a patient with Parry-Romberg syndrome (P4.064)
Conclusions:The only other reported patient with PRS and stroke was also found to have a PFO. It is possible that the elevated ANA seen in this patient correlates with propensity towards small venous clots not seen on ultrasound. This may lead to paradoxical emboli and ischemic strokes. It is important to note this potential association between PRS and ischemic stroke in young patients without other known risk factors. It would be worthwhile to treat this subset of patients with medications for secondary stroke prevention.Disclosure: Dr. Ebiana has nothing to disclose. Dr. Singh has nothing to disclose. Dr. Khosa has nothi...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ebiana, V., Singh, S., Khosa, S., Moheb, N., Trikamji, B., Rao, N., Mishra, S. Tags: General Neurology: Vascular Neurology Source Type: research

Relation of Intracranial Stenosis and Elevated Carotid Intimal Medial Thickness in Black Caribbean Ischemic Stroke Patients (P03.187)
CONCLUSIONS: Our preliminary results suggest that increased MCA velocity is independent elevated CIMT, a biomarker for atherosclerosis, in anterior circulation ischemic stroke in CBs. History of hypercholesterolemia appears to be an important risk factor in atherosclerosis in CBs. This data suggests further prospective studies of MCA stenosis mechanisms in CBs are warranted.Disclosure: Dr. Law has nothing to disclose. Dr. Hao has nothing to disclose. Dr. Rojas-Soto has nothing to disclose. Dr. Yu has nothing to disclose. Dr. Baird has received personal compensation for activities as a speaker at the International Conferenc...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Law, S., Hao, Q., Rojas-Soto, D., Yu, H., Baird, A. Tags: P03 Cerebrovascular Disease III Source Type: research

Which Diagnostic Tests For Stroke Are The Most Costly And May Not Be Necessary? (P2.126)
CONCLUSIONS: We found that charges for a basic stroke work up within a single metropolitan area varied by four fold. Individual tests varied by up to a factor of eight. Expensive tests which have not been shown to affect treatment decisions (such as brain MRA or CTA) could be affected under new systems of health care payment. Greater transparency in pricing could reduce costs for common diagnostic tests in stroke.Study Supported by: NoneDisclosure: Dr. Rajamani has nothing to disclose. Dr. Bhattacharya has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Chaturvedi, S., Rajamani, K., Bhattacharya, P. Tags: Cerebrovascular Disease and Interventional Neurology: Evaluation, Cost, and Quality Source Type: research

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