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Source: Neurology
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Total 1979 results found since Jan 2013.

Cerebral blood flow and auto-regulation in acute TIA patients from a general hospital in Qatar (P4.253)
Conclusions:Preliminary results indicate the feasibility of TCD and BHI in acute evaluation of TIA patients for purpose of prognosis and functional outcome. Further studies are necessary to confirm their clinical value.Study Supported by: This research was supported by QNRF (a member of Qatar foundation) and NPRP No. 6-565-3-141. The opinions expressed are the sole responsibility of the authors.Disclosure: Dr. Musthak has nothing to disclose. Dr. Dimassi has nothing to disclose. Dr. Akhtar has nothing to disclose. Dr. Kamran has nothing to disclose. Dr. Abbasi has nothing to disclose. Dr. Khattab has nothing to disclose. D...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Musthak, A., Dimassi, D., Akhtar, N., Kamran, S., Abbasi, S., Khattab, A., El Sotouhy, A., Haddad, N., Streletz, L. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Sigmoid Sinus Characteristics Correlate with Early Clinical and Imaging Surrogates in Anterior Circulation Ischemic Stroke (P4.254)
Conclusions:The finding of an outflow pattern independent of the stroke site implicates an involvement of the cerebral venous drainage system in the pathophysiology of ischemic stroke.Disclosure: Dr. Sellner has received personal compensation for activities with Bayer, Biogen Idec, Merck-Serono, Novartis, Genzyme, and Teva. Dr. Magdic has nothing to disclose. Dr. Liebeskind has received personal compensation for activities with Stryker and Covidien as a consultant. Dr. Karamyan has nothing to disclose. Dr. Bubel has nothing to disclose. Dr. McCoy has nothing to disclose. Dr. Pikija has received personal compensation for ac...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Sellner, J., Magdic, J., Liebeskind, D., Karamyan, A., Bubel, N., McCoy, M., Pikija, S. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Infarct location predicts outcome in distal MCA occlusions (P4.255)
Conclusions:ASPECTS regions M3 and M6 are key predictors of functional outcome following isolated distal MCA infarction. These findings will be helpful in stratifying outcomes if validated in future studies.Disclosure: Dr. Khan has nothing to disclose. Dr. Baird has nothing to disclose. Dr. Goddeau has nothing to disclose. Dr. Silver has received personal compensation for activities with Women's Health Initiative, SOCRATES trial, MedLink, Medscape, and Ebix. Dr. Henninger has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Khan, M., Baird, G., Goddeau, R., Silver, B., Henninger, N. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Factors Affecting Distal Hyperintense Vessel Sign, a Postulated Marker for Intracranial Collateral Circulation (P4.256)
Conclusions:We note consistencies between prior studies and our study showing that younger patients without hypertension have better collaterals. We also found an association of diabetes with less DHVS whereas prior studies have yielded an inconsistent association. While a correlation between stroke severity and stroke volume could not be confirmed, low power and wide stroke-to-MRI gap (range 1–8 d) were important limitations here. Further study correcting these shortcomings is warranted. In conclusion, our findings support the origins of DHVS from collateral circulation and are affected by traditional cerebrovascula...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Girotra, T., Affan, M., Marin, H., Schultz, L., Miller, D. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Clinical and imaging characteristics of silent brain infarction and symptomatic stroke (P4.257)
Conclusions:In an imaging-defined brain infarct cohort, SBI is highly prevalent and encompasses a spectrum of clinical presentations. The majority of individuals with SBI have no documented symptoms or deficits.Disclosure: Dr. Albazli has nothing to disclose. Dr. Leung has nothing to disclose. Dr. Huggins has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Albazli, K., Leung, L., Huggins, H. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Early cognitive decline in symptomatic carotid stenosis is related to plaque inflammation and concomitant intracranial stenosis (P4.258)
Conclusions:Early cognitive decline is common among patients with symptomatic stenosis of the extracranial carotid artery, especially when associated with concomitant intracranial stenosis and plaque inflammation.Study Supported by: This study is supported by a grant from the National Medical Research Council, Singapore.Disclosure: Dr. Tan has nothing to disclose. Dr. Bharatendu has nothing to disclose. Dr. Paliwal has nothing to disclose. Dr. Teoh has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Dong has nothing to disclose. Dr. Sinha has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tan, C. H., Bharatendu, C., Paliwal, P., Teoh, H. L., Chan, B., Dong, Y., Sinha, A., Sharma, V. K. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Vasa Vasorum Enhancement on Computerized Tomographic Angiography Correlates with Symptomatic Patients with 50% to 70% Carotid Artery Stenosis (P4.259)
Conclusions:In patients with 50% to 70% ICA stenosis, VV enhancement recognized on computed tomographic angiography is strongly associated with acute neurological symptoms compared with calcified and nonenhancing-noncalcified arterial plaques. This finding may aid in the identification of patients at increased risk for ischemic stroke within populations with the same degree of stenosis.Disclosure: Dr. Pizzolato Umeton has nothing to disclose. Dr. Romero has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pizzolato Umeton, R., Romero, J. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Association between Increased Brachial-ankle Pulse Wave Velocity and Cerebral Perivascular Space (P4.260)
Conclusions:Increased baPWV was independently associated with severity of cerebral PVS, especially in younger individuals. This finding provided further evidences of the relationship between arterial stiffness and cerebral small vessel disease.Study Supported by:National Natural Science Foundation of China (grant number: 81173663), and National Key Technology R&D Program in the 12th five-year Plan of China (grant number: 2012BAJ18B04-3, 2015AA020506)Disclosure: Dr. Zhai has nothing to disclose. Dr. Ye has nothing to disclose. Dr. Chen has nothing to disclose. Dr. Ding has nothing to disclose. Dr. Han has nothing to dis...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Zhai, F.-F., Ye, Y.-C., Chen, S.-Y., Ding, F.-M., Han, F., Yang, X.-L., Zhou, L.-X., Ni, J., Yao, M., Li, M.-L., Jin, Z.-Y., Cui, L.-Y., Zhang, S.-Y., Zhu, Y.-C. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Quick-brain MRI as first imaging modality to diagnose pediatric stroke (P4.261)
Conclusions:QB was the most common first study, was sensitive for acute stroke, and resulted in rapid diagnosis, with no missed findings. This small study suggests that QB may be considered as a first study in children with symptoms of acute stroke.Disclosure: Dr. Christy has nothing to disclose. Dr. Wilson has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Christy, A., Wilson, J. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Early Clinical Improvement in Central Retinal Artery Occlusion is Associated with Central Retinal Artery Recanalization (P4.262)
Conclusions:In our case series, no patient without early recanalization of the CRA had ECI. Further studies are merited to determine the impact of CRA recanalization timing and, furthermore, whether fibrinolytic therapy is associated with improved CRA recanalization rates and long-term visual acuity in CRAO patients.Disclosure: Dr. Alkuwaiti has nothing to disclose. Dr. Male has nothing to disclose. Dr. Hendriksen has nothing to disclose. Dr. Engel has nothing to disclose. Dr. Reshi has nothing to disclose. Dr. Ezzeddine has received personal compensation for activities with Air Liquide as a Scientific Advisory Board membe...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Alkuwaiti, M., Male, S., Hendriksen, S., Engel, K., Reshi, R. A., Ezzeddine, M., Emiru, T., Logue, C., Streib, C. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Minor Strokes with proximal large vessel occlusion in anterior circulation; is intravenous thrombolysis enough (P4.265)
Conclusions:Despite the overall perception that this condition is benign, nearly half of our patients treated with IVT did not achieve independence on discharge. Our result suggest that potential need for endovascular treatment in such patients and designing a larger controlled study is recommended.Disclosure: Dr. Kamal has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Vakharia has nothing to disclose. Dr. Sawyer has nothing to disclose. Dr. Kamal has nothing to disclose. Dr. Mowla has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Kamal, H., Ahmad, M. K., Vakharia, K., Sawyer, R., Shallwani, H., Mowla, A. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Imaging predictors of hemorrhagic transformation following intravenous rt-PA treatment for acute ischemic stroke. (P4.266)
Conclusions:Presence of one or more chronic microbleeds is associated with increased risk of HT following rt-PA administration.Disclosure: Dr. Tasneem has nothing to disclose. Dr. Shaban has nothing to disclose. Dr. Dandapat has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Policeni has nothing to disclose. Dr. Olalde has nothing to disclose. Dr. Samaniego has nothing to disclose. Dr. Shim has nothing to disclose. Dr. Pieper has nothing to disclose. Dr. Leira has nothing to disclose. Dr. Ortega-Gutierrez has nothing to disclose. Dr. Adams has nothing to disclose. Dr. Nagaraja has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tasneem, N., Shaban, A., Dandapat, S., Ahmed, U., Policeni, B., Olalde, H., Samaniego, E., Shim, H., Pieper, C., Leira, E. C., Ortega-Gutierrez, S., Adams, H. P., Nagaraja, N. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Symptomatic Intracranial Hemorrhage after IV tPA for Acute Ischemic Stroke Patients with Relative Contraindications to Treatment (P4.267)
Conclusions:12 AIS patients with Class 3 exclusion criteria were treated with IV tPA. Our eight cases of IV tPA in pICH patients adds substantially to the existing literature. In this study, 25% of patients with pICH developed symptomatic ICH after IV tPA. Although the low number of eligible patients limits interpretation of our findings, continued caution when considering IV tPA for AIS patients with pICH may be warranted. More data is needed to clarify the impact these relative contraindications have on the treatment of AIS.Disclosure: Dr. Smith has nothing to disclose. Dr. Alkuwaiti has nothing to disclose. Dr. Bell has...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Smith, K., Alkuwaiti, M., Bell, C., Lindsay, D., Heyer, A., Reshi, R., Ezzeddine, M., Streib, C. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Impact of Vascular Risk factors on Hemorrhagic Transformation Following rt-PA Administration for Acute Ischemic Stroke (P4.269)
Conclusions:No vascular risk factor was independently associated with HT, suggesting a confounding effect from stroke severity (NIHSS score).Disclosure: Dr. Shaban has nothing to disclose. Dr. Tasneem has nothing to disclose. Dr. Dandapat has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Policeni has nothing to disclose. Dr. Olalde has nothing to disclose. Dr. Samaniego has nothing to disclose. Dr. Shim has nothing to disclose. Dr. Pieper has nothing to disclose. Dr. Leira has nothing to disclose. Dr. Ortega-Gutierrez has nothing to disclose. Dr. Adams has nothing to disclose. Dr. Nagaraja has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Shaban, A., Tasneem, N., Dandapat, S., Ahmed, U., Policeni, B., Olalde, H., Samaniego, E., Shim, H., Pieper, C., Leira, E., Ortega-Gutierrez, S., Adams, H., Nagaraja, N. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Collaborative Interventions Reduce Time-to-Thrombolysis for Acute Ischemic Stroke in an Urban, Public Hospital (P4.270)
Conclusions:Targeted, multidisciplinary, collaborative interventions are associated with substantial and significant reductions in time to thrombolysis. Such targeted interventions are effective and feasible in the unique setting of a public safety net hospital.Disclosure: Dr. Threlkeld has nothing to disclose. Dr. Kozak has nothing to disclose. Dr. Cole has nothing to disclose. Dr. Martin has nothing to disclose. Dr. Singh has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Threlkeld, Z., Kozak, B., Cole, S., Martin, C., Singh, V. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research