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Source: Neurology
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Total 38 results found since Jan 2013.

Comparison of On-hour vs Off-hour Patient Cohorts at a Primary Stroke Center: Onset-To-Treatment Duration and Clinical Outcomes after IV Thrombolysis (S21.005)
CONCLUSIONS: We found no significant differences in OTT durations, stroke severity, or stroke outcomes between patients whose symptoms originated during on-hours vs off-hours. This represents progress in emergency response, recognition and acute stroke care delivered by our Emergency Department staff and acute stroke team on a 24 hour basis and likely reflects nationwide efforts to provide consistent care for acute stroke patients.Disclosure: Dr. Nystrom has nothing to disclose. Dr. Asuzu has nothing to disclose. Dr. Amin has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Wira has nothing to disclose. Dr. ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Nystrom, K., Asuzu, D., Amin, H., Schindler, J., Wira, C., Greer, D., Chi, N. F., Halliday, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: Prehospital and Acute Ischemic Stroke Treatment Source Type: research

Summary of evidence-based guideline update: Prevention of stroke in nonvalvular atrial fibrillation: Report of the Guideline Development Subcommittee of the American Academy of Neurology
Objective: To update the 1998 American Academy of Neurology practice parameter on stroke prevention in nonvalvular atrial fibrillation (NVAF). How often do various technologies identify previously undetected NVAF? Which therapies reduce ischemic stroke risk with the least risk of hemorrhage, including intracranial hemorrhage? The complete guideline on which this summary is based is available as an online data supplement to this article. Methods: Systematic literature review; modified Delphi process recommendation formulation. Major conclusions: In patients with recent cryptogenic stroke, cardiac rhythm monitoring probabl...
Source: Neurology - February 24, 2014 Category: Neurology Authors: Culebras, A., Messe, S. R., Chaturvedi, S., Kase, C. S., Gronseth, G. Tags: All Cerebrovascular disease/Stroke SPECIAL ARTICLE Source Type: research

Recognition and management of stroke in young adults and adolescents
Approximately 15% of all ischemic strokes (IS) occur in young adults and adolescents. To date, only limited prior public health and research efforts have specifically addressed stroke in the young. Early diagnosis remains challenging because of the lack of awareness and the relative infrequency of stroke compared with stroke mimics. Moreover, the causes of IS in the young are heterogeneous and can be relatively uncommon, resulting in uncertainties about diagnostic evaluation and cause-specific management. Emerging data have raised public health concerns about the increasing prevalence of traditional vascular risk factors i...
Source: Neurology - September 16, 2013 Category: Neurology Authors: Singhal, A. B., Biller, J., Elkind, M. S., Fullerton, H. J., Jauch, E. C., Kittner, S. J., Levine, D. A., Levine, S. R. Tags: Childhood stroke, Stroke in young adults, All Cerebrovascular disease/Stroke, Carotid artery dissection, Infarction VIEWS & amp;amp; REVIEWS Source Type: research

Practice advisory: Recurrent stroke with patent foramen ovale (update of practice parameter): Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology
Conclusions: Percutaneous PFO closure with the STARFlex device possibly does not provide a benefit in preventing stroke vs medical therapy alone (risk difference [RD] 0.13%, 95% confidence interval [CI] –2.2% to 2.0%). Percutaneous PFO closure with the AMPLATZER PFO Occluder possibly decreases the risk of recurrent stroke (RD –1.68%, 95% CI –3.18% to –0.19%), possibly increases the risk of new-onset atrial fibrillation (AF) (RD 1.64%, 95% CI 0.07%–3.2%), and is highly likely to be associated with a procedural complication risk of 3.4% (95% CI 2.3%–5%). There is insufficient evidence to d...
Source: Neurology - August 21, 2016 Category: Neurology Authors: Messe, S. R., Gronseth, G., Kent, D. M., Kizer, J. R., Homma, S., Rosterman, L., Kasner, S. E. Tags: All Cerebrovascular disease/Stroke SPECIAL ARTICLE Source Type: research

Does Prior Use of Beta Blockers Affect Functional Outcomes Post Ischemic Stroke Endovascular Intervention? (P5.296)
Conclusions:Prior use of beta blockers did not lead to better functional outcomes (MRS ≤2) in acute ischemic stroke patients undergoing EVI. Findings should be further confirmed in larger population.Disclosure: Dr. Albadareen has nothing to disclose. Dr. Gronseth has received personal compensation in an editorial capacity for Neurology. Dr. Gronseth has received research support from the American Academy of Neurology. Dr. Mittal has nothing to disclose. Dr. Sharrock has nothing to disclose. Dr. Keshary has nothing to disclose. Dr. Abraham has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Albadareen, R., Gronseth, G., Mittal, M., Sharrock, M., Keshary, S., Abraham, M. Tags: Stroke Recovery and Rehabilitation Source Type: research

The Discharge Modified Rankin Scale Score Correlates with Established Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis (P7.118)
Conclusions: Discharge MRS scores showed robust agreement with at least 3 HT scores known to predict long-term functional outcomes after IV rt-PA therapy. Therefore, readily available discharge MRS scores may be useful indicator of patients requiring closer follow-up after IV rt-PA therapy.Disclosure: Dr. Asuzu has nothing to disclose. Dr. Nystrom has nothing to disclose. Dr. Halliday has nothing to disclose. Dr. Wira has nothing to disclose. Dr. Greer has nothing to disclose. Dr. Pritchard has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Sheth has received research support from the American Academy of N...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Asuzu, D., Nystrom, K., Halliday, J., Wira, C., Greer, D., Pritchard, D., Schindler, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment Source Type: research

A Mobile Application for Predicting 90-day Outcomes after IV Thrombolysis in Ischemic Stroke (P3.069)
CONCLUSIONS: We evaluated the ability of our score to predict 90-day outcomes and developed an iOS application based on results. Our mobile application brings a unique opportunity to optimize rT-PA treatment decisions for acute ischemic stroke patients.Disclosure: Dr. Nystrom has nothing to disclose. Dr. Asuzu has nothing to disclose. Dr. Amin has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Wira has nothing to disclose. Dr. Greer has received personal compensation in an editorial capacity for Seminars in Neurology. Dr. Chi has nothing to disclose. Dr. Halliday has nothing to disclose. Dr. Sheth has rece...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Nystrom, K., Asuzu, D., Amin, H., Schindler, J., Wira, C., Greer, D., Chi, N. F., Halliday, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Predictors of Return To Driving after Stroke (P03.157)
CONCLUSIONS: Patients with higher FIM cognition and lower extremity Motricity Index scores at admission to inpatient rehabilitation are more likely to return to driving at six months. This model could be used by rehabilitation professionals to help counsel patients and their families and focus treatment goals.Supported by: American Academy of Neurology, NIH National Center for Advancing Translational Sciences, HealthSouth Corporation, Washington University McDonnell Center for Systems Neuroscience, and the Foundation for Barnes-Jewish Hospital.Disclosure: Dr. Aufman has nothing to disclose. Dr. Bland has received personal ...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Aufman, E., Bland, M., Barco, P., Carr, D., Lang, C. Tags: P03 Cerebrovascular Disease III Source Type: research

HAT Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis (P3.109)
Conclusions: HAT score yielded the highest odds ratio among the 4 scores that accurately predicted sICH in our independent dataset. HAT score also had low computational complexity compared to other scores. Our results demonstrate the potential utility of the HAT score as a predictor of adverse clinical outcome for acute ischemic stroke patients undergoing IV thrombolytic therapy.Disclosure: Dr. Asuzu has nothing to disclose. Dr. Nystrom has nothing to disclose. Dr. Halliday has nothing to disclose. Dr. Wira has nothing to disclose. Dr. Greer has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Sheth has rece...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Asuzu, D., Nystrom, K., Halliday, J., Wira, C., Greer, D., Schindler, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: t-PA Source Type: research

Randomized Controlled Trial Of Constraint-Induced Aphasia Therapy In Patients With Chronic Stroke (S21.001)
Conclusions: Overall, this randomized controlled trial did not show improvement in language abilities in this small group of subjects with chronic post-stroke aphasia receiving CIAT when compared to observation.Disclosure: Dr. Szaflarski has received personal compensation for activities with UCB Pharma. Dr. Szaflarski has received research support from the National Institutes of Health, the American Academy of Neurology, the Shor Foundation for Epilepsy Research, Neuren, and Eisai Inc. Dr. Allendorfer has received research support from the Shor Foundation for Epilepsy Research. Dr. Ball has nothing to disclose. Dr. Banks h...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Szaflarski, J., Allendorfer, J., Ball, A., Banks, C., Dietz, A., Hart, K., Lindsell, C., Martin, A., Vannest, J. Tags: Neuro-rehabilitation and Neural Repair Source Type: research

Summary of evidence-based guideline: Periprocedural management of antithrombotic medications in patients with ischemic cerebrovascular disease: Report of the Guideline Development Subcommittee of the American Academy of Neurology
Objective: To assess evidence regarding periprocedural management of antithrombotic drugs in patients with ischemic cerebrovascular disease. The complete guideline on which this summary is based is available as an online data supplement to this article. Methods: Systematic literature review with practice recommendations. Results and recommendations: Clinicians managing antithrombotic medications periprocedurally must weigh bleeding risks from drug continuation against thromboembolic risks from discontinuation. Stroke patients undergoing dental procedures should routinely continue aspirin (Level A). Stroke patients underg...
Source: Neurology - May 27, 2013 Category: Neurology Authors: Armstrong, M. J., Gronseth, G., Anderson, D. C., Biller, J., Cucchiara, B., Dafer, R., Goldstein, L. B., Schneck, M., Messe, S. R. Tags: Ultrasound, All Medical/Systemic disease, All Neuro-ophthalmology, All Cerebrovascular disease/Stroke, All Trauma SPECIAL ARTICLE Source Type: research

Kinematic and Kinetic Outcome of Robot Assisted Neurorehabilitation in Chronic Moderate-to-Severe Hemiparetic Stroke (P3.298)
Conclusions: RT+TTT was not significantly different from RT alone, suggesting that TTT did not interfere with motor learning conferred by RT. Study Supported by: American Academy of Neurology (AAN) and the VA Department of Research and Development VA Merit Award B6935RDisclosure: Dr. Iqbal has nothing to disclose. Dr. Conroy has nothing to disclose. Dr. Roy has nothing to disclose. Dr. Bever has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Iqbal, T., Conroy, S., Roy, A., Bever, C. Tags: Neurorehabilitation Source Type: research

Teleneurology applications: Report of the Telemedicine Work Group of the American Academy of Neurology
Conclusions: Teleneurology is an effective tool for the rapid evaluation of patients in remote locations requiring neurologic care. These underserved locations include geographically isolated rural areas as well as urban cores with insufficient available neurology specialists. With this technology, neurologists will be better able to meet the burgeoning demand for access to neurologic care in an era of declining availability. An increase in physician awareness and support at the federal and state level is necessary to facilitate expansion of telemedicine into further areas of neurology.
Source: Neurology - February 11, 2013 Category: Neurology Authors: Wechsler, L. R., Tsao, J. W., Levine, S. R., Swain-Eng, R. J., Adams, R. J., Demaerschalk, B. M., Hess, D. C., Moro, E., Schwamm, L. H., Steffensen, S., Stern, B. J., Zuckerman, S. J., Bhattacharya, P., Davis, L. E., Yurkiewicz, I. R., Alphonso, A. L., Fo Tags: All Movement Disorders, All Cerebrovascular disease/Stroke, Models of care, All Practice Management, All Education CONTEMPORARY ISSUES Source Type: research

Longer Door to Needle Times When Fellows Administer Tissue Plasminogen Activator via Telemedicine (P2.359)
Conclusions: DTN was longer over TM than in our ED. While our findings imply that NFVs may have taken a longer time to administer IV tPA, further studies are needed to determine what are the causative factors and how to address them.Disclosure: Dr. Jagolino has nothing to disclose. Dr. Bozorgui has nothing to disclose. Dr. Cossey has nothing to disclose. Dr. Ankrom has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Irani has nothing to disclose. Dr. Vahidy has nothing to disclose. Dr. Savitz has received research support from NIH T32 grant. Dr. Wu has received personal compensation for activities with Genentech.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Jagolino, A., Bozorgui, S., Cossey, T., Ankrom, C., Patel, J., Irani, M., Vahidy, F., Savitz, S., Wu, T.-C. Tags: Education Research: Graduate Medical Education Source Type: research

Systematic Review and Meta-Analysis of Cohort Studies Examining Effect of Anticoagulation and Risk of Cerebral Hemorrhage in patients with Cerebral Microbleeds (P2.276)
Conclusions:Results of this meta-analysis suggest that patients with CMBs started on anticoagulation after ischemic stroke are more likely to have ICH outcomes than patients without CMBs. However, the study was limited by small sample sizes based on extracted data and lack of quality prospective cohort studies meeting inclusion criteria. Further investigation is necessary to conclude increased risk of ICH in this patient population.Disclosure: Dr. Faheem has nothing to disclose. Dr. Wang has received research support from TEVA Pharmaceuticals Ltd. Dr. Gronseth has received personal compensation in an editorial capacity for...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Faheem, N., Wang, Y., Gronseth, G. Tags: Intracerebral Hemorrhage Source Type: research