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Long-Term Risk of Stroke, Seizures and Cognitive Impairment After Transient Global Amnesia: A Case-Control, Population-Based Study with Long Term Follow Up (P1.114)
Conclusions: The long-term risk of stroke, seizure and cognitive impairment is not increased after TGA. Migraine appears to be a risk factor for presenting TGA.Disclosure: Dr. Arena has nothing to disclose. Dr. Mandrekar has nothing to disclose. Dr. Singh has nothing to disclose. Dr. Brown has nothing to disclose. Dr. Rabinstein has received royalty payments from Elsevier and Oxford University Press. Dr. Rabinstein has received research support from DJO Global.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Arena, J., Mandrekar, J., Singh, T., Brown, R., Rabinstein, A. Tags: Neuroepidemiology: Cerebrovascular Disease Source Type: research

Utility of Brain MRI in Infective Endocarditis (S46.004)
CONCLUSIONS: In hospitalized patients with IE, ICH was associated with unfavorable clinical outcomes. However, in patients undergoing valve surgery, microbleeds on MRI were not associated with development of postoperative ICH. Preoperative brain MRI may result in a delay to surgery and did not have an impact on outcome. Thus, the clinical utility of brain MRI in patients with IE remains uncertain.Disclosure: Dr. Chakraborty has nothing to disclose. Dr. Scharf has nothing to disclose. Dr. DeSimone has nothing to disclose. Dr. Abdelghani has nothing to disclose. Dr. Rabinstein has received royalty payments from Elsevier and ...
Source: Neurology - February 7, 2016 Category: Neurology Authors: Chakraborty, T., Scharf, E., DeSimone, D., Abdelghani, E.-R., Rabinstein, A., Wijdicks, E., Baddour, L., Fugate, J. Tags: Critical Care Source Type: research

Promoting Locomotor Learning with Spinal Direct Current Stimulation- Pilot Data (S28.005)
CONCLUSION: After interim analysis, we repowered the study and determined that 14 additional healthy volunteers per group will be needed, to achieve a statistical significance of 97.5 percent and a power of 0.80. Results gathered at this stage will allow us to further assess the effect of tDCS at different stages of locomotor learning, including online, offline, and total learning-- necessary for application in future neurorehabilitation trials involving patients with spinal cord injury and stroke. Study Supported by: Intramural Research Program, NINDSDisclosure: Dr. Awosika has nothing to disclose. Dr. Sandrini has nothin...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Awosika, O., Sandrini, M., Volochayev, R., Xu, B., Floeter, M. K., Hallett, M., Cohen, L. Tags: Neuro-rehabilitation Source Type: research

Routine troponin measurements are unnecessary in acute ischemic stroke evaluations (P4.285)
CONCLUSIONS: Troponin elevation in patients with ischemic stroke is not caused by acute myocardial ischemia unless iatrogenic in the setting of vasopressor administration. Serum troponins should be measured based on clinical context rather than routinely in all acute ischemic stroke patients.Disclosure: Dr. Ali has nothing to disclose. Dr. Young has nothing to disclose. Dr. Rabinstein has received royalty payments from Elsevier and Oxford University Press. Dr. Rabinstein has received research support from DJO Global. Dr. Flemming has nothing to disclose. Dr. Fugate has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ali, F., Young, J., Rabinstein, A., Flemming, K., Fugate, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Ischemic Stroke Care Source Type: research

NeurologicManifestations of Neglected Tropical Diseases (P4.295)
CONCLUSIONS: Neurological manifestations of NTDs cause significant morbidity and mortality, although data are limited. The evidence for treatments of neurologic complications is limited for most NTDs. Increased awareness of neurologic manifestations of NTDs can promote early identification and treatment, thereby contributing to ongoing elimination and eradication campaigns.Study Supported by: NADisclosure: Dr. Raibagkar has nothing to disclose. Dr. Berkowitz has received royalty payments from Medmaster and Oxford University Press. Dr. Pritt has nothing to disclose. Dr. Headley-Whyte has nothing to disclose. Dr. Mateen has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Raibagkar, P., Berkowitz, A., Pritt, B., Headley-Whyte, E. T., Mateen, F. Tags: Global Health and Infection Source Type: research

Aspirin for Acute Stroke of Undetermined Etiology in Resource-Limited Settings: A Decision Analysis (P4.296)
CONCLUSIONS: Aspirin initiation after acute stroke of unknown etiology in resource-limited settings is predicted to decrease acute stroke-related mortality and stroke recurrence. The assumption that aspirin cannot be safely administered to patients with acute stroke of unknown etiology without neuroimaging to assess for ICH is not supported by our model. In the absence of a clinical trial to test this approach empirically, clinical decisions still require patient-specific scrutiny.Disclosure: Dr. Berkowitz has received royalty payments from Medmaster and Oxford University Press. Dr. Westover has received personal compensat...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Berkowitz, A., Westover, M., Bianchi, M., Chou, S. Tags: Global Health and Infection Source Type: research

Response to IncobotulinumtoxinA After Resistance to OnabotulinumtoxinA and RimabotulinumtoxinB (P7.061)
CONCLUSIONS:Switching to incobotulinumtoxinA after secondary resistance to onabotulinumtoxinA and rimabotulinumtoxinB may be a viable treatment option in dystonia.Study Supported by:National Institutes of Health- National Institutes of Neurological Diseases and Stroke and the Dystonia Medical Research FoundationDisclosure: Dr. Ramos has received personal compensation for activities with the National Inistitutes of Health as an employee, and the Dystonia Medical Research Foundation. Dr. Karp has nothing to disclose. Dr. Lungu has nothing to disclose. Dr. Alter has nothing to disclose. Dr. Hallett has received personal compe...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramos, V., Karp, B., Lungu, C., Alter, K., Hallett, M. Tags: Movement Disorders: Dystonia Treatment Source Type: research

Tricks to Treatments: Sensory Tricks in Dystonia (P2.042)
CONCLUSIONS:We propose a new classification of ST,to include its variants, such as FT, MT, IT and rST. Wide range of prevalence and effectiveness of ST may reflect ambiguity of terminology and varying measures. More studies are needed to determine the interaction of deep brain stimulation and botulinum toxin with ST. Our research points to more benefit than harm for searching for, or even inducing, ST in patients with dystonia.Study Supported by:National Institutes of Health and the National Institute of Neurological Disorders and Stroke, and the the Dystonia Medical Research Foundation.Disclosure: Dr. Ramos has received p...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramos, V., Karp, B., Hallett, M. Tags: Movement Disorders: Dystonia Source Type: research

High Accordance Rate of Neurologist Referrals for Psychogenic Patients with Expert Opinion at the Movement Disorders Screening Clinic at the Human Motor Control Section of the National Institute of Neurologic Disorders and Stroke (S49.006)
CONCLUSIONS:Neurologist referrals to the Movement Disorders Screening Clinic at the Human Motor Control Section of the National Institute of Neurologic Disorders and Stroke of psychogenic patients have a high accordance rate (94%) with expert opinion from our Institution.Study Supported by:NIH-NINDSDisclosure: Dr. Ramos has received personal compensation for activities with the National Inistitutes of Health as an employee, and the Dystonia Medical Research Foundation. Dr. Villegas has nothing to disclose. Dr. Esquenazi has nothing to disclose. Dr. Hallett has received personal compensation for activities with Neurotoxin I...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramos, V., Villegas, M. A. F., Esquenazi, A., Hallett, M. Tags: Practice, Policy, and Ethics Source Type: research

Quantitative Video-oculography to Differentiate Stroke from Vestibular Neuritis in Acute Vertigo-Vestibulo-ocular Reflex Gain Distributions and Optimal Test Thresholds for Diagnosis (P6.289)
CONCLUSIONS: Peripheral and central causes of AVS can be differentiated by quantitative, portable video-oculography. Some AICA strokes mimic vestibular neuritis closely. Disclosure: Dr. Saber Tehrani has nothing to disclose. Dr. Mantokoudis has nothing to disclose. Dr. Wozniak has nothing to disclose. Dr. Eibenberger has nothing to disclose. Dr. Kattah has received personal compensation for activities with Pfizer, Inc. as a consultant. Dr. Guede has nothing to disclose. Dr. Zee has received personal compensation for activities with Sun Pharma and Abbott. Dr. Zee has received royalty payments from Oxford Universi...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Saber Tehrani, A., Mantokoudis, G., Wozniak, A., Eibenberger, K., Kattah, J., Guede, C., Zee, D., Newman-Toker, D. Tags: Neuro-ophthalmology/Neuro-otology II Source Type: research

Vertigo and Dizziness in Anterior Circulation Cerebrovascular Disease: A Systematic Review (P3.092)
CONCLUSIONS: Vertigo and dizziness are not rare manifestations of carotid territory ischemia, particularly in the temporo-parietal regions. Although dizziness is generally more prevalent in women, anterior circulation stroke causing dizziness appears to be more prevalent in men. Clinicians should carefully consider a search for anterior circulation vascular disease in patients presenting with vestibular symptoms.Disclosure: Dr. Zhou has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Mantokoudis has nothing to disclose. Dr. Saber Tehrani has nothing to disclose. Dr. Ying has nothing to disclose. Dr. Kerber has re...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Zhou, Y., Lee, S.-H., Mantokoudis, G., Saber Tehrani, A., Ying, S., Kerber, K., Hsieh, Y.-H., Robinson, K., Hanley, D., Zee, D., Newman-Toker, D. Tags: Cerebrovascular Disease and Interventional Neurology: Clinical Management Source Type: research