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Source: Neurology
Condition: Migraine

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Total 247 results found since Jan 2013.

Exploring Protein Quantitation Methods to Detect Useful Plasma Biomarkers for Distinguishing Ischemic Stroke from Mimic (P6.009)
Conclusions: These results provide proof of concept that proteomic signals can be useful in ACVS diagnosis in more severe cases.The analyses have shaped our prospective verification (completed, n=560) and validation studies (ongoing, n=1200) of the use of proteomics in the diagnosis of mimic vs. mild-ACVS in early Emergency Department triage.Disclosure: Dr. Penn has received personal compensation for activities with Pfizer, Boehringer Ingelheim Pharmaceuticals, Inc., and Bayer as a speaker. Dr. Balshaw has nothing to disclose. Dr. Lesperance has nothing to disclose. Dr. Saly has nothing to disclose. Dr. Jackson has nothing...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Penn, A., Balshaw, R., Lesperance, M., Saly, V., Jackson, A., Smith, D., Votova, K., Lu, L., Morrison, J., Coutts, S., Borchers, C. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

Facial Colliculus and Opalski Stroke Syndromes Caused by Vertebral Artery Dissection. Case Report (P4.349)
Conclusion: Brainstem stroke syndromes are challenging to localize before brain imaging. In this case two embolic strokes happened. The first in the right facial colliculus causing the right 6th and 7th cranial nerves palsy. The second happened in the left lateral medulla extending below the pyramidal decussation causing a classical left lateral medullary syndrome with ipsilateral hemiparesis, which constitute a left Opalski stroke syndrome.Disclosure: Dr. Alghamdi has nothing to disclose. Dr. Ayoub has nothing to disclose. Dr. Alzahrani has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Alghamdi, S., Ayoub, O., Alzahrani, N. Tags: Cerebrovascular Case Reports Source Type: research

Matrix Metalloproteinase Levels in Cervical and Intracranial Carotid Dolichoarteriopathies (P4.371)
Conclusions: MMP-2 may play a role in the etiology of DE or kink /tortuosity of carotid artery may cause elevation of MMP-2 in plasma. MMP-12 levels increases in carotid atherosclerotic lesions and may lead plaque formation. In future, MMP inhibitor therapies may appear to be a choice for the treatment of atherosclerotic plaques or DE.Disclosure: Dr. Arslan has nothing to disclose. Dr. Arslan has nothing to disclose. Dr. Pekçevik has nothing to disclose. Dr. Şener has nothing to disclose. Dr. Köse has nothing to disclose. Dr. Zorlu has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Arslan, Y., Arslan, I. B., Pekcevik, Y., Şener, U., Kose, Şukran, Zorlu, Y. Tags: Cerebrovascular Case Reports Source Type: research

HSV-2 Encephalitis Presenting as Multifocal Ischemic Stroke (P4.375)
CONCLUSION A high index of suspicion needs to be maintained to diagnose infectious vasculitis. A history of immunosuppression and headache preceding cerebral infarction were important factors that ultimately led to the appropriate work up and diagnosis in this case. Lumbar puncture and prompt initiation of antiviral treatment is essential in stroke case of suspected CNS infection with HSV-2.Disclosure: Dr. Zhang has nothing to disclose. Dr. Sumida has nothing to disclose. Dr. Margolesky has nothing to disclose. Dr. Tornes has nothing to disclose. Dr. Ramos has nothing to disclose. Dr. Koch has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zhang, F., Sumida, A., Margolesky, J., Tornes, L., Ramos, A., Koch, S. Tags: Cerebrovascular Case Reports Source Type: research

Pain after Cervical Artery Dissection (P4.381)
Conclusions: Chronic pain or new pain development is frequent after spontaneous CAD. Recognition of clinical factors that predict chronic pain could help clinicians manage pain in CAD patients more effectively.Disclosure: Dr. Youn has nothing to disclose. Dr. Prabhakaran has received personal compensation for activities with the American Heart Association.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Youn, J., Prabhakaran, S. Tags: Non-Atherosclerotic Arteriopathies Source Type: research

Internal Carotid Artery Stenosis and Flow Diversion: Relationship with Headache (P6.099)
Conclusion: Recognition of flow-diversion into the ECA as a possible mechanism for headaches may help in further understanding of ICA disease, its progression, and effects of carotid revascularization on quality of life. Headache as a likely surrogate marker of carotid stenosis with flow-diversion warrants more research, and may be critical in the early identification of significant ICA stenosis and prevention of TIA or stroke.Disclosure: Dr. Herial has nothing to disclose. Dr. Miran has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Herial, N., Miran, M. S., Saleem, M., Qureshi, I., Qureshi, A. Tags: Headache: Clinical Presentation/Diagnosis Source Type: research

Retinal Vasculopathy and Cerebral Leukodystrophy (RVCL) in a Spanish Family (P5.269)
CONCLUSIONS: Retinal Vasculopathy and Cerebral Leucodistrophy (RVCL) is a rare but devastating autosomal-dominant condition of middle-age onset presenting with progressive retinopathy, neuropsychiatric deterioration and other sistemic symptoms. Investigation of additional families should help to categorize the spectrum this entity and thus prevent underdiagnnosis, avoid invasive tests and develop some tipe of treatment.Disclosure: Dr. ALVAREZ has nothing to disclose. Dr. Rodriguez Rodriguez has nothing to disclose. Dr. REIGOSA has nothing to disclose. Dr. Seijo-Martinez has nothing to disclose. Dr. Cortes Laino has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Alvarez, L., Rodriguez Rodriguez, M., Reigosa, R., Seijo-Martinez, M., Cortes Laino, J. A. Tags: General Neurology: Genetics Source Type: research

Status Epilepticus in Patients with SMART (P5.012)
CONCLUSIONS We describe three patients with SMART presenting with SE. Our cases raise the concern that SMART is not necessarily a migraine phenomenon but can be a form of focal SE associated with stroke-like symptoms. In patients with radiographic suspicion of SMART we suggest a low threshold for vEEG monitoring and aggressive anti-epileptic management.Disclosure: Dr. Fan has nothing to disclose. Dr. Gabriel has nothing to disclose. Dr. Gerard has nothing to disclose. Dr. Schuele has received personal compensation for activities with Sunovion and Eisai as a speaker.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Fan, P., Gabriel, H., Gerard, E., Schuele, S. Tags: Neuromuscular Disease and Epilepsy ePoster Session Source Type: research

Cerebral perfusion in stroke-like migraine attacks after radiation therapy syndrome
We present 2 patients with recurrent attacks of SMART syndrome with increased cerebral blood volume in affected regions and abnormal vascular reactivity on transcranial Doppler ultrasound, suggesting a potential mechanism.
Source: Neurology - February 22, 2016 Category: Neurology Authors: Olsen, A. L., Miller, J. J., Bhattacharyya, S., Voinescu, P. E., Klein, J. P. Tags: MRI, All Clinical Neurology, All Cerebrovascular disease/Stroke, Radiation therapy-tumor CLINICAL/SCIENTIFIC NOTES Source Type: research

Bilateral occipital strokes from an atherosclerotic trigeminal artery
A 58-year-old man with coronary disease presented with headache, confusion, and vision loss. On examination, he had retrograde and anterograde amnesia, superior homonymous quadrantanopias, and could not identify colors. MRI showed bilateral occipital infarcts involving the parahippocampal and lingual gyri (figure 1). CT angiography revealed a hypoplastic vertebrobasilar circulation, with a persistent right trigeminal artery supplying the rostral basilar artery (figure 2). Persistent fetal arteries may increase risk of atherogenesis due to increased turbulence.1 A rare cortical syndrome, new-onset achromatopsia with amnesia...
Source: Neurology - February 1, 2016 Category: Neurology Authors: Miller, E. C., Willey, J. Z. Tags: All Imaging, All Cerebrovascular disease/Stroke NEUROIMAGES Source Type: research

Long-term use of daily sumatriptan injections in severe drug-resistant chronic cluster headache
Chronic cluster headache (CCH) is a rare but severely debilitating condition.1 Some patients have drug-resistant CCH and continue to have daily attacks using abortive agents for long periods many times per day, mainly subcutaneous sumatriptan (SS).2 According to pharmaceutical company indications, the maximum SS dosage is 2 injections (12 mg) per day but these patients often use more. This limitation appears reasonable because of single case reports of cardiac arrest attributable to SS vasoconstrictive properties.3,4 Usually these events occur at the initial administration, and an underlying occult coronary artery disease ...
Source: Neurology - January 11, 2016 Category: Neurology Authors: Leone, M., Proietti Cecchini, A. Tags: All Headache, Cluster headache, Patient safety CLINICAL/SCIENTIFIC NOTES Source Type: research

Cerebral hyperperfusion on arterial spin labeling MRI during CADASIL migrainous encephalopathy
Migrainous encephalopathy is a rare and poorly understood manifestation of the inherited vasculopathy cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Patients may present with migraine with aura, complicated by confusion, fever, and decreased conscious level.1 In this case, a patient with migrainous encephalopathy underwent cerebral perfusion imaging with arterial spin labeling (ASL) MRI before, during, and following admission.
Source: Neurology - December 14, 2015 Category: Neurology Authors: Moreton, F. C., Santosh, C., McArthur, K., Muir, K. W. Tags: Migraine, MRI, All Cerebrovascular disease/Stroke, CADASIL CLINICAL/SCIENTIFIC NOTES Source Type: research

Migraine makes the stroke grow faster?
Long associated with increased incidence of stroke,1,2 migraine has been linked with mechanisms involving the vasculature (vasospasm, arterial dissection, endothelial dysfunction, venous thrombosis), heart (patent foramen ovale), and blood (hypercoagulability).3 Since cerebral ischemia can induce cortical spreading depression, the physiologic process underlying aura, migraine with aura may theoretically represent a TIA equivalent in a subset of people. In addition to the heightened occurrence of stroke in migraineurs, a growing body of evidence suggests more dire consequences when stroke occurs, with experiments in mice wi...
Source: Neurology - November 30, 2015 Category: Neurology Authors: Tietjen, G. E., Sacco, S. Tags: Migraine, All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Sensitivity to acute cerebral ischemic injury in migraineurs: A retrospective case-control study
Conclusions: This case-control study supports the hypothesis that a history of migraine, particularly with aura, is associated with a no-mismatch pattern during acute ischemic stroke, consistent with data obtained in migraine mutant mice.
Source: Neurology - November 30, 2015 Category: Neurology Authors: Mawet, J., Eikermann-Haerter, K., Park, K.-Y., Helenius, J., Daneshmand, A., Pearlman, L., Avery, R., Negro, A., Velioglu, M., Arsava, E. M., Ay, H., Ayata, C. Tags: Migraine, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Clinical Reasoning: A 50-year-old man with "elephantiasis" and headache
A 50-year-old man with a medical history of "elephantiasis" of the legs, status post left above the knee amputation with prosthetic limb, and hypothyroidism presented with 1 week of headache and nausea. The headache was continuous, with gradual worsening over the 7 days prior to admission, and he had minimal relief with ibuprofen. On the second day, he developed nausea. He denied any history of headaches, blurred or double vision, numbness, weakness, tingling, loss of balance, vertigo, chest pain, palpitations, or shortness of breath. In the emergency room, he was afebrile with a heart rate of 78 beats per minute and regul...
Source: Neurology - November 23, 2015 Category: Neurology Authors: Yaghi, S., Kitago, T., Elkind, M. S. V. Tags: All Cerebrovascular disease/Stroke, Embolism, Infarction RESIDENT AND FELLOW SECTION Source Type: research