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Source: Neurology
Condition: Dementia

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Total 240 results found since Jan 2013.

Probable REM sleep behavior disorder and risk of stroke: A prospective study
Conclusions: Presence of pRBD was associated with a higher risk of developing stroke, including both ischemic and hemorrhagic types. Future studies with clinically confirmed RBD and a longer follow-up would be appropriate to further investigate this association.
Source: Neurology - May 8, 2017 Category: Neurology Authors: Ma, C., Pavlova, M., Liu, Y., Liu, Y., Huangfu, C., Wu, S., Gao, X. Tags: All Cerebrovascular disease/Stroke, All Sleep Disorders, Cohort studies ARTICLE Source Type: research

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke
Conclusions: Genetic associations with WMHV are shared in otherwise healthy individuals and patients with stroke, indicating common genetic susceptibility in cerebral small vessel disease.
Source: Neurology - January 11, 2016 Category: Neurology Authors: Traylor, M., Zhang, C. R., Adib-Samii, P., Devan, W. J., Parsons, O. E., Lanfranconi, S., Gregory, S., Cloonan, L., Falcone, G. J., Radmanesh, F., Fitzpatrick, K., Kanakis, A., Barrick, T. R., Moynihan, B., Lewis, C. M., Boncoraglio, G. B., Lemmens, R., T Tags: MRI, All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, All Genetics, Association studies in genetics ARTICLE Source Type: research

Structural MRI markers of brain aging early after ischemic stroke
Conclusions: Brain structure is likely to be compromised before ischemic stroke by vascular risk factors. Smaller hippocampal and total brain volumes and increased WMH load represent proxies for underlying vascular brain injury.
Source: Neurology - July 10, 2017 Category: Neurology Authors: Werden, E., Cumming, T., Li, Q., Bird, L., Veldsman, M., Pardoe, H. R., Jackson, G., Donnan, G. A., Brodtmann, A. Tags: MRI, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Alzheimer's disease, Vascular dementia ARTICLE Source Type: research

Risk of incident stroke in patients with Alzheimer disease or vascular dementia
Conclusions: Patients with VD, but not AD, have a markedly higher risk of developing an ischemic stroke than those without dementia. In patients with AD, but not VD, use of atypical antipsychotic drugs was associated with an increased risk of TIA.
Source: Neurology - September 2, 2013 Category: Neurology Authors: Imfeld, P., Bodmer, M., Schuerch, M., Jick, S. S., Meier, C. R. Tags: All Cerebrovascular disease/Stroke, Alzheimer's disease, Vascular dementia, Case control studies, Incidence studies ARTICLE Source Type: research

Subclinical cardiac dysfunction increases the risk of stroke and dementia: The Rotterdam Study
Conclusions: In elderly free of clinical cardiac disease, worse diastolic function is associated with clinical stroke, dementia, and silent infarcts on MRI, whereas worse systolic function is related only to clinical stroke. These findings can form the basis for future research on the utility of cardiac function as potential intervention target for prevention of neurologic diseases.
Source: Neurology - February 23, 2015 Category: Neurology Authors: de Bruijn, R. F. A. G., Portegies, M. L. P., Leening, M. J. G., Bos, M. J., Hofman, A., van der Lugt, A., Niessen, W. J., Vernooij, M. W., Franco, O. H., Koudstaal, P. J., Ikram, M. A. Tags: MRI, All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, Cohort studies ARTICLE Source Type: research

Failing a Dysphagia Screening Test after Acute Ischemic Stroke: Baseline Patient Factors and Outcomes (P6.037)
CONCLUSIONS: Patients with ischemic stroke who failed a dysphagia screening test had worse pre-admission function and more severe strokes, and developed much higher rates of complications and death than those who passed. Multivariable analyses are pending to control for stroke severity and determine the strength of these associations.Disclosure: Dr. Joundi has nothing to disclose. Dr. Martino has nothing to disclose. Dr. Saposnik has nothing to disclose. Dr. Fang has nothing to disclose. Dr. Giannakeas has nothing to disclose. Dr. Kapral has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Joundi, R., Martino, R., Saposnik, G., Fang, J., Giannakeas, V., Kapral, M. Tags: In-Hospital Stroke and Stroke Complications Source Type: research

Gender Differences in Post Stroke Fatigue (P5.290)
Conclusions:In our urban predominately minority cohort, women had more severe PSF than men. The basis for the protective effect of HTN on PSF severity is unclear and deserves further study.Disclosure: Dr. Balucani has nothing to disclose. Dr. Gilles has nothing to disclose. Dr. Singer has nothing to disclose. Dr. Stefanov has nothing to disclose. Dr. Halket has nothing to disclose. Dr. Mlastabi has nothing to disclose. Dr. Huang has nothing to disclose. Dr. Weingast has nothing to disclose. Dr. Levine has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Balucani, C., Gilles, N., Singer, J., Stefanov, D., Halket, D., Mlastabi, J., Huang, A., Weingast, S., Levine, S. Tags: Stroke Recovery and Rehabilitation Source Type: research

Report of stroke-like symptoms predicts incident cognitive impairment in a stroke-free cohort
Conclusions: Report of SS/TIA showed a strong association with incident cognitive impairment and supports the use of the Questionnaire for Verifying Stroke-free Status as a quick, low-cost instrument to screen for people at increased risk of cognitive decline.
Source: Neurology - July 8, 2013 Category: Neurology Authors: Kelley, B. J., McClure, L. A., Letter, A. J., Wadley, V. G., Unverzagt, F. W., Kissela, B. M., Kleindorfer, D., Howard, G. Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, Vascular dementia, All epidemiology ARTICLE Source Type: research

Association of Hemoglobin A1c and Baseline Ischemic Stroke Severity: A Population-Based Study (P1.187)
Conclusions: We found that elevated HbA1c was associated with decreased stroke severity at presentation. However, this effect is mediated by the history of DM rather than a specific dose-effect of glycemic control. Our results provide evidence that although chronic hyperglycemia increases risk of stroke, it is not associated with increased stroke severity.Disclosure: Dr. Yang has nothing to disclose. Dr. Khoury has nothing to disclose. Dr. Alwell has nothing to disclose. Dr. Moomaw has received research support from the National Institutes of Health. Dr. Yeramaneni has nothing to disclose. Dr. Woo has received research sup...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Yang, Y., Khoury, J., Alwell, K., Moomaw, C., Yeramaneni, S., Woo, D., Flaherty, M., Adeoye, O., Ferioli, S., De Los Rios La Rosa, F., Kissela, B., Kleindorfer, D. Tags: Ischemic Stroke Outcomes Source Type: research

Executive function, but not memory, associates with incident coronary heart disease and stroke
Conclusion: Lower executive function, but not memory, is associated with higher risk of coronary heart disease and stroke. Lower executive function, as an independent risk indicator, might better reflect brain vascular pathologies.
Source: Neurology - August 31, 2015 Category: Neurology Authors: Rostamian, S., van Buchem, M. A., Westendorp, R. G. J., Jukema, J. W., Mooijaart, S. P., Sabayan, B., de Craen, A. J. M. Tags: All Cerebrovascular disease/Stroke, Cardiac, Cognitive aging, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Increasing comorbidity and health services utilization in older adults with prior stroke
Conclusions: Our findings demonstrate the importance of community-based patient-centered care strategies for stroke survivors that address their range of health needs and prevent more costly acute care use.
Source: Neurology - November 13, 2016 Category: Neurology Authors: Gruneir, A., Griffith, L. E., Fisher, K., Panjwani, D., Gandhi, S., Sheng, L., Patterson, C., Gafni, A., Ploeg, J., Markle-Reid, M. Tags: All Health Services Research, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

The complexities of acute stroke decision-making: A survey of neurologists
Conclusions: This study provides evidence for the presence of uncertainty, beliefs, and biases in acute stroke decision-making. This survey should be considered a preliminary investigation of the multiple factors implicit in IV tPA administration.
Source: Neurology - September 23, 2013 Category: Neurology Authors: Shamy, M. C. F., Jaigobin, C. S. Tags: Decision analysis, CT, All Clinical Neurology, All Cerebrovascular disease/Stroke, Professional conduct and ethics ARTICLE Source Type: research

Natural Autoantibodies in the Serum of Post-Stroke Patients with Different Clinical Outcomes (P7.146)
CONCLUSIONS:Pronounced decrease of serum levels of IgG NAbs at 3 month is the important biomarker predicting post-stroke cognitive impairment.Disclosure: Dr. Guekht has nothing to disclose. Dr. Gusev has nothing to disclose. Dr. Alferova has nothing to disclose. Dr. Gulyaeva has nothing to disclose. Dr. Poletaev has nothing to disclose. Dr. Yakovlev has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Guekht, A., Gusev, E., Alferova, V., Gulyaeva, N., Poletaev, A., Yakovlev, A. Tags: Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke Source Type: research

Elderly Non-Demented Patients Have Better Outcome with Reperfusion Therapy Than Demented Patients Following Ischemic Stroke (P7.150)
Conclusion:Non-demented elderly patients perform nearly as well as younger patients with ischemic stroke when treated appropriately with IV/IA TPA. Reperfusion therapy should be considered in treating non-demented elderly patients in contrast to elderly patients with dementia.Disclosure: Dr. Duggal has nothing to disclose. Dr. Myers has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Ahmed has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Duggal, N., Myers, T., Kim, J., Ahmed, I. Tags: Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke Source Type: research

Thrombolytic therapy for stroke in patients with preexisting cognitive impairment
Conclusions: Ischemic stroke patients with PSCI should receive rtPA if they are eligible. This conclusion cannot be extended to severe cognitive impairment or severe strokes. Classification of evidence: This study provides Class IV evidence that in patients with PSCI presenting with acute ischemic stroke, IV rtPA improves outcomes.
Source: Neurology - June 9, 2014 Category: Neurology Authors: Murao, K., Leys, D., Jacquin, A., Kitazono, T., Bordet, R., Bejot, Y., Kimura, K., Godefroy, O., Wakisaka, Y., Moulin, S., Ago, T., Sibon, I., Bombois, S., Mas, J.-L., Henon, H., Pasquier, F., Giroud, M., Cordonnier, C., Okada, Y., On behalf of the OPHELI Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, MCI (mild cognitive impairment), Infarction ARTICLE Source Type: research