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Source: International Journal of Stroke
Procedure: PET Scan

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Total 24 results found since Jan 2013.

Stroke in Bahrain: rising incidence, multiple risk factors, and suboptimal care
The incidence of stroke in Bahrain is rising in the Bahraini population and has nearly doubled over the last 16 years, while the incidence in the non‐Bahraini population has not changed. Incidence of stroke in the Bahraini population (110/100 000) is now much greater than in the non‐Bahraini population (27/100 000). The Bahraini stroke population is 10 years younger than Western comparators with a much higher prevalence of many of the risk factors for stroke, including diabetes (54%), hypertension (75%) and hyperlipidemia (34%). The combination of an ageing Bahraini population alongside a high prevalence of risk fa...
Source: International Journal of Stroke - April 1, 2015 Category: Neurology Authors: Mona Al Banna, Hassan Baldawi, Ali Kadhim, Hani Humaidan, David L. Whitford Tags: Panorama Source Type: research

Effects of candesartan in acute stroke on vascular events during long‐term follow‐up: results from the Scandinavian Candesartan Acute Stroke Trial (SCAST)
ConclusionsTreatment with candesartan in the acute phase of stroke was not associated with clear long‐term clinical benefits. This result supports the conclusion from trials with short‐term follow‐up, that blood pressure lowering treatment with candesartan should not be given routinely to patients with acute stroke and raised blood pressure.
Source: International Journal of Stroke - March 23, 2015 Category: Neurology Authors: Astrid G. Hornslien, Else C. Sandset, Jannicke Igland, Andreas Terént, Gudrun Boysen, Philip M. W. Bath, Gordon D. Murray, Eivind Berge Tags: Research Source Type: research

Carotid plaque inflammation assessed with 18F‐FDG PET/CT is higher in symptomatic compared with asymptomatic patients
Conclusion18F‐FDG uptake on PET/CT correlated with histological assessments of inflammation and was higher in patients with symptomatic compared with asymptomatic carotid artery plaques. These results support the use of 18F‐FDG PET/CT in the detection inflammation in carotid atherosclerosis, which may be of help in the detection of vulnerable plaques.
Source: International Journal of Stroke - January 15, 2015 Category: Neurology Authors: Karolina Skagen, Kjersti Johnsrud, Kristin Evensen, Helge Scott, Kirsten Krohg‐Sørensen, Frode Reier‐Nilsen, Mona‐Elisabeth Revheim, Jan Gunnar Fjeld, Mona Skjelland, David Russell Tags: Research Source Type: research

Effects of blood pressure lowering in patients with acute ischemic stroke and carotid artery stenosis
ConclusionsThere is no clear evidence that the effect of candesartan is qualitatively different in patients with carotid artery stenosis, but there are signals that patients with severe stenosis are at particularly high risk of stroke progression and poor functional outcome.
Source: International Journal of Stroke - December 3, 2014 Category: Neurology Authors: Mirza Jusufovic, Else Charlotte Sandset, Philip M. W. Bath, Björn W. Karlson, Eivind Berge, Tags: Research Source Type: research

Poststroke fatigue: risk factors and its effect on functional status and health‐related quality of life
ConclusionDepressive symptoms and prestroke fatigue are major correlates of poststroke fatigue while more severe poststroke fatigue is associated with poorer activities of daily living and health‐related quality of life.
Source: International Journal of Stroke - December 3, 2014 Category: Neurology Authors: Yang‐Kun Chen, Jian‐Feng Qu, Wei‐Min Xiao, Wan‐Yi Li, Han‐Yu Weng, Wei Li, Yong‐Lin Liu, Gen‐Pei Luo, Xue‐Wen Fang, Gabor S. Ungvari, Yu‐Tao Xiang Tags: Research Source Type: research

Recent advances in TeleStroke: a systematic review on applications in prehospital management and Stroke Unit treatment or TeleStroke networking in developing countries
TeleStroke has become an increasing means to overcome shortage of stroke expertise in underserved areas. This rapidly growing field has triggered a large amount of publications in recent years. We aimed to analyze recent advances in the field of telemedicine for acute stroke, with main focus on prehospital management, Stroke Unit treatment and network implementations in developing countries. Out of 260 articles, 25 were selected for this systematic review: 9 regarding prehospital management, 14 regarding Stroke Unit treatment and 2 describing a network in developing countries. Prehospital management showed that stroke reco...
Source: International Journal of Stroke - November 10, 2014 Category: Neurology Authors: Gordian J. Hubert, Peter Müller‐Barna, Heinrich J. Audebert Tags: Review Source Type: research

World Stroke Organization Global Stroke Services Guidelines and Action Plan
Every two seconds, someone across the globe suffers a symptomatic stroke. ‘Silent’ cerebrovascular disease insidiously contributes to worldwide disability by causing cognitive impairment in the elderly. The risk of cerebrovascular disease is disproportionately higher in low to middle income countries where there may be barriers to stroke care. The last two decades have seen a major transformation in the stroke field with the emergence of evidence‐based approaches to stroke prevention, acute stroke management, and stroke recovery. The current challenge lies in implementing these interventions, particularly in regions ...
Source: International Journal of Stroke - September 23, 2014 Category: Neurology Authors: Patrice Lindsay, Karen L. Furie, Stephen M. Davis, Geoffrey A. Donnan, Bo Norrving Tags: Guidelines Source Type: research

Baseline characteristics of the 4011 patients recruited into the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial
ConclusionENOS is a large completed international trial of blood pressure management in acute stroke and includes patients representative of many stroke services worldwide.
Source: International Journal of Stroke - July 1, 2014 Category: Neurology Tags: Research Source Type: research

Trimming the fat in acute ischemic stroke: an assessment of 24‐h CT scans in tPA patients
ConclusionsOur results demonstrate that routine 24‐h computed tomography scan in patients without 24‐h National Institute of Health Stroke Scale worsening (especially those with baseline National Institute of Health Stroke Scale ≤10) is less likely to yield information that results in a deviation from standard acute stroke care. No patient without worsening and baseline National Institute of Health Stroke Scale ≤10 had parenchymal hematoma on 24‐h computed tomography. Application of the National Institute of Health Stroke Scale to distinguish patients who should have 24‐h follow‐up imaging from those who will...
Source: International Journal of Stroke - June 3, 2014 Category: Neurology Authors: Alexander J. George, Amelia K. Boehme, Casey R. Dunn, T. Beasley, James E. Siegler, Karen C. Albright, Ramy El Khoury, Sheryl Martin‐Schild Tags: Research Source Type: research

Processes of early stroke care and hospital costs
ConclusionsEarly care in agreement with key guidelines recommendations for the management of patients with stroke may be associated with hospital savings.
Source: International Journal of Stroke - December 19, 2013 Category: Neurology Authors: Marie Louise Svendsen, Lars H. Ehlers, Heidi H. Hundborg, Annette Ingeman, Søren P. Johnsen Tags: Research Source Type: research

Interdependence of stroke outcome scales: reliable estimates from the Virtual International Stroke Trials Archive (VISTA)
ConclusionCorrelations and partial correlations among stroke outcome scales in trial datasets are higher than previously reported. The new estimates are more reliable for trial planning due to the sample size and diversity.
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: F. C. Goldie, R. L. Fulton, B. Frank, K. R. Lees, Tags: Systematic review Source Type: research

Establishment of an effective acute stroke telemedicine program for Australia: protocol for the Victorian Stroke Telemedicine project
RationaleUrgent treatment of acute stroke in rural Australia is problematic partly because of limited access to medical specialists. Utilization of telemedicine could improve delivery of acute stroke treatments in rural communities. AimThe study aims to demonstrate enhanced clinical decision making for use of thrombolysis within 4·5 h of ischemic stroke symptom onset in a rural setting using a telemedicine specialist support model. DesignA formative program evaluation research design was used. The Victorian Stroke Telemedicine program was developed and will be evaluated over five stages to ensure successful implementati...
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Dominique A. Cadilhac, Natasha Moloczij, Sonia Denisenko, Helen Dewey, Peter Disler, Bruce Winzar, Ian Mosley, Geoffrey A. Donnan, Christopher Bladin Tags: Protocols Source Type: research

Perfusion computed tomography thresholds defining ischemic penumbra and infarct core: studies in a rat stroke model
ConclusionsThe data provide perfusion computed tomography defined relative cerebral blood flow thresholds for infarct core and ischemic penumbra within the first two hours after experimental stroke in rats. These thresholds were shown to be stable to define the volume of infarct core and penumbra within this time window.
Source: International Journal of Stroke - October 21, 2013 Category: Neurology Authors: D. D. McLeod, M. W. Parsons, R. Hood, B. Hiles, J. Allen, S. K. McCann, L. Murtha, M. B. Calford, C. R. Levi, N. J. Spratt Tags: Research Source Type: research

The CLOQS trial protocol: a cluster‐randomized trial evaluating a simple, low‐cost intervention to reduce treatment times in acute stroke
The objective of the Countdown Lights to Optimize Quality in acute Stroke (CLOQS) trial is to determine whether a simple, low‐cost organizational behavior intervention, a large, red stopwatch timer attached to the stretcher upon arrival, will decrease door‐to‐scanner and door‐to‐needle treatment times for tissue plasminogen activator‐treated patients. DesignA multicenter, time‐clustered randomized control trial. The stopwatch timers will be used in Emergency Departments for all acute stroke patients across the University of Toronto Stroke Program. The order of intervention (ON) and control (OFF) blocks will b...
Source: International Journal of Stroke - September 5, 2013 Category: Neurology Authors: Richard H. Swartz, Michelle N. Sicard, Frank L. Silver, Gustavo Saposnik, David J. Gladstone, Jennifer Breaton, Sharon Ramagnano, Jacques Lee, Richard I. Aviv, Jiming Fang, Merrick F. Zwarenstein, Tags: Protocols Source Type: research

Coexistence of internal carotid artery stenosis with intracranial aneurysm
ConclusionsAlthough low in absolute occurrence, there is a significant correlation of the existence of an intracranial aneurysm with carotid artery stenosis. Thus, if peripheral stenosis is detected by any imaging modality including carotid Ultrasonography scan, we recommend digital subtraction intracranial angiography to detect any potential aneurysm and define its radiologic morphology.
Source: International Journal of Stroke - August 26, 2013 Category: Neurology Authors: Yongping Liang, Jun Wang, Baomin Li Tags: Research Source Type: research