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Rehabilitation in chronic spatial neglect strengthens resting state connectivity
ConclusionIntense VR training that improved left sided awareness in chronic stroke patients also increased sporadic interhemispheric functional connectivity within the DAN. Specifically, a region responsible for saccadic eye movement to the left became more integrated with the left posterior parietal cortex. These results highlight a mechanism that should be exploited in the training of patients with chronic visuospatial neglect.This article is protected by copyright. All rights reserved.
Source: Acta Neurologica Scandinavica - November 14, 2018 Category: Neurology Authors: Anders W åhlin, Helena Fordell, Urban Ekman, Niklas Lenfeldt, Jan Malm Tags: Original Article Source Type: research

Long ‐term progression of white matter hyperintensities in ischemic stroke
ConclusionsAge and marked WMH at index stroke, but not stroke subtype, predicted long ‐term WMH progression after ischemic stroke before 70 years of age, whereas age and hypertension predicted acquisition of marked WMH in those with no or only mild WMH at baseline.
Source: Acta Neurologica Scandinavica - November 4, 2018 Category: Neurology Authors: Lukas Holmegaard, Christer Jensen, Petra Redfors, Christian Blomstrand, Christina Jern, Katarina Jood Tags: ORIGINAL ARTICLE Source Type: research

Contrast ‐enhanced sonothrombolysis in acute ischemic stroke patients without intracranial large‐vessel occlusion
ConclusionCEST is safe in ischemic stroke patients without intracranial LVO. There were no differences in clinical outcomes between the treatment groups.
Source: Acta Neurologica Scandinavica - October 25, 2017 Category: Neurology Authors: C. E. Kvistad, A. Nacu, V. Novotny, N. Logallo, U. Waje ‐Andreassen, H. Naess, L. Thomassen Tags: ORIGINAL ARTICLE Source Type: research

Accelerated atherosclerosis in ANCA ‐associated vasculitis
ConclusionsOur study adds weight to the presence of increased atherosclerosis in AAV‐patients. The association observed between CIMT and PI‐ICA with small vessel cerebral disease, points the possible association of easy to use carotid US in predicting microvascular brain injury.
Source: Acta Neurologica Scandinavica - June 13, 2017 Category: Neurology Authors: I. Gonz ález‐Suárez, J. J. Ríos‐Blanco, J. Arpa Tags: ORIGINAL ARTICLE Source Type: research

Cerebrospinal fluid and blood flow patterns in idiopathic normal pressure hydrocephalus
ConclusionsThe typical flow of blood and CSF in INPH was mainly characterized by increased CSF pulsatility in the aqueduct and reduced cervical CSF pulsatility. The direction of mean net aqueduct CSF flow was from the third to the fourth ventricle. Our findings may reflect the altered distribution of intracranial CSF volume in INPH, although the causality of these relationships is unclear.
Source: Acta Neurologica Scandinavica - July 8, 2016 Category: Neurology Authors: S. Qvarlander, K. Ambarki, A. Wåhlin, J. Jacobsson, R. Birgander, J. Malm, A. Eklund Tags: Original Article Source Type: research

Ischemic stroke subtype is associated with outcome in thrombolyzed patients
ConclusionsCardioembolic stroke patients were more likely to achieve early neurological improvement and favorable outcome compared with LVD stroke following MRI‐based IV‐tPA treatment. This finding may reflect a difference in the effect of IV‐tPA among stroke subtypes.
Source: Acta Neurologica Scandinavica - March 17, 2016 Category: Neurology Authors: M. L. Schmitz, C. Z. Simonsen, M. L. Svendsen, H. Larsson, M. H. Madsen, I. K. Mikkelsen, M. Fisher, S. P. Johnsen, G. Andersen Tags: Original Article Source Type: research

C‐reactive protein levels are associated with cerebral small vessel‐related lesions
ConclusionsHigher levels of hs‐CRP were associated with lacunar infarcts. Thus, inflammatory processes may be involved in the pathogenesis of small‐vessel disease.
Source: Acta Neurologica Scandinavica - May 15, 2015 Category: Neurology Authors: S. Mitaki, A. Nagai, H. Oguro, S. Yamaguchi Tags: Original Article Source Type: research

Predicting intracerebral hemorrhage by baseline magnetic resonance imaging in stroke patients undergoing systemic thrombolysis
ConclusionsIn ischemic stroke patients within 3 h from symptom onset, the existence of FLAIR‐positive lesions on pretreatment MRI is significantly associated with an increased bleeding risk due to systemic thrombolysis. Therefore, considering FLAIR‐positive lesions on baseline MRI might guide treatment decisions in ischemic stroke.
Source: Acta Neurologica Scandinavica - July 18, 2014 Category: Neurology Authors: C. Hobohm, D. Fritzsch, S. Budig, J. Classen, K.‐T. Hoffmann, D. Michalski Tags: Original Article Source Type: research

Spontaneous ischaemic stroke in dogs: clinical topographic similarities to humans
ConclusionsSpontaneously occurring ischaemic stroke in dogs share characteristics with human ischaemic stroke in terms of clinical symptoms and infarct topography. Investigating pet dogs with spontaneous ischaemic stroke may provide an alternative approach to the research of stroke injury mechanisms as they occur naturally, and should be further investigated.
Source: Acta Neurologica Scandinavica - February 7, 2013 Category: Neurology Authors: H. Gredal, G. C. Skerritt, P. Gideon, P. Arlien‐Soeborg, M. Berendt Tags: Clinical Commentary Source Type: research