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Prevalence and predictors of anxiety in an African sample of recent stroke survivors
ConclusionsOne in five recent stroke survivors in SSA has clinically significant anxiety, and well over 70% of those with anxiety also have depression. Future studies will need to determine what specific impact post‐stroke anxiety may have on post‐stroke clinical processes and outcomes.
Source: Acta Neurologica Scandinavica - April 18, 2017 Category: Neurology Authors: A. Ojagbemi, M. Owolabi, R. Akinyemi, O. Arulogun, J. Akinyemi, O. Akpa, F. S. Sarfo, E. Uvere, R. Saulson, S. Hurst, B. Ovbiagele Tags: ORIGINAL ARTICLE Source Type: research

Small vessel disease and clinical outcomes after IV rt ‐PA treatment
ConclusionOur results suggest that SVD negatively affects stroke outcomes after intravenous thrombolysis. Although white matter changes seem to be the major driver in relation to worse outcomes, global estimation of SVD is feasible and may provide helpful information.
Source: Acta Neurologica Scandinavica - February 24, 2017 Category: Neurology Authors: F. Arba, D. Inzitari, M. Ali, S. J. Warach, M. Luby, K. R. Lees, Tags: ORIGINAL ARTICLE Source Type: research

Preexisting cognitive impairment in intracerebral hemorrhage
ConclusionsIn conclusion, cognitive impairment frequently precedes ICH. A higher frequency of cerebrovascular events suggests a role of vascular processes in the development of cognitive impairment before ICH.
Source: Acta Neurologica Scandinavica - August 9, 2016 Category: Neurology Authors: M. Laible, S. Horstmann, M. M öhlenbruch, S. Schueler, T. Rizos, R. Veltkamp Tags: Original Article Source Type: research

Determinants of post‐stroke cognitive impairment: analysis from VISTA
ConclusionsBesides well‐known determinants of PSCI such as age, stroke severity and the presence of vascular risk factors, also leg paralysis is associated with subsequent of PSCI up to 3 years after stroke.
Source: Acta Neurologica Scandinavica - July 14, 2016 Category: Neurology Authors: F. Arba, T. Quinn, G. J. Hankey, D. Inzitari, M. Ali, K. R. Lees, Tags: Original Article Source Type: research

Determinants of post ‐stroke cognitive impairment: analysis from VISTA
ConclusionsBesides well‐known determinants of PSCI such as age, stroke severity and the presence of vascular risk factors, also leg paralysis is associated with subsequent of PSCI up to 3 years after stroke.
Source: Acta Neurologica Scandinavica - July 12, 2016 Category: Neurology Authors: F. Arba, T. Quinn, G. J. Hankey, D. Inzitari, M. Ali, K. R. Lees, Tags: Original Article Source Type: research

APOE and AGT in the Finnish p.Arg133Cys CADASIL population
ConclusionsThe APOE, AGT and NOTCH3 polymorphism did not modify the onset of strokes or migraine in our CADASIL sample, which is one of the largest mutationally homogenous CADASIL populations published to date. International collaboration, pooled analyses and genomewide approaches are warranted to identify the genetic factors that modify the highly variable CADASIL phenotype.
Source: Acta Neurologica Scandinavica - March 26, 2015 Category: Neurology Authors: M. Siitonen, K. Mykkänen, F. Pescini, S. Rovio, H. Kääriäinen, M. Baumann, M. Pöyhönen, M. Viitanen Tags: Clinical Commentary Source Type: research

Burden and cost of neurological diseases: a European North–South comparison
ConclusionsHealth expenditure, YLDs, costs and prevalence of neurological conditions were generally not correlated across the eight countries. A clear North–South gradient was found for health expenditures, and partially for YLDs, costs and diseases' prevalence. We hypothesized that this is a consequence of the expansion of morbidity of neurological conditions connected to ageing, that health and welfare systems of selected countries were not prepared to face.
Source: Acta Neurologica Scandinavica - October 23, 2014 Category: Neurology Authors: A. Raggi, M. Leonardi Tags: Original Article Source Type: research

Changing clinical patterns and increasing prevalence in CADASIL
ConclusionsCADASIL prevalence is at least 4.6 per 100,000 adults. Median age of first stroke may be older than previously thought. Clinicians should consider CADASIL in the differential diagnosis even in older patients with stroke.
Source: Acta Neurologica Scandinavica - April 1, 2014 Category: Neurology Authors: F. C. Moreton, S. S. M. Razvi, R. Davidson, K. W. Muir Tags: Original Article Source Type: research