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Source: JAMA Neurology
Condition: Stroke
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Total 364 results found since Jan 2013.
Error in Table
The Original Investigation titled “Association Between Alberta Stroke Program Early Computed Tomography Score and Efficacy and Safety Outcomes With Endovascular Therapy in Patients With Stroke From Large-Vessel Occlusion: A Secondary Analysis of the Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism—Japan Large I schemic Core Trial (RESCUE-Japan LIMIT),” published online October 10, 2022, was corrected to add 2 missing P values in Table 2.
Source: JAMA Neurology - December 12, 2022 Category: Neurology Source Type: research
Predictors of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease
This prespecified analysis of the Stroke of Known Cause and Underlying Atrial Fibrillation (STROKE AF) randomized clinical trial investigates the association of commonly assessed risk factors with undiagnosed atrial fibrillation in patients with ischemic stroke from large- or small-vessel disease.
Source: JAMA Neurology - November 14, 2022 Category: Neurology Source Type: research
Association of Stroke and Cerebrovascular Pathologies With Scam Susceptibility in Older Adults
This cohort study examines the association of diverse cerebrovascular pathologies (globally and regionally) with scam susceptibility in older adults.
Source: JAMA Neurology - October 31, 2022 Category: Neurology Source Type: research
Monogenic Stroke —Can We Overcome Nature With Nurture?
Although genetic underpinnings of several neurological disorders like epilepsy have been described as early as fourth century bce in the Corpus Hippocraticum, discoveries in stroke have been more recent. One of the first reports demonstrating the importance of heredity in stroke pathogenesis occurred in 1974 with the generation of the stroke-prone spontaneously hypertensive rat. This strain was created using selective breeding and has endured as a valuable asset in contemporary stroke research. Nonetheless, half a century later, the precise genetic determinants even in this single, highly specific rodent stroke phenotype h...
Source: JAMA Neurology - October 27, 2022 Category: Neurology Source Type: research
Association of Vascular Risk Factors and Genetic Factors With Penetrance of Variants Causing Monogenic Stroke
This cohort study examines data from UK Biobank participants who had whole-exome sequencing to determine the frequency of pathogenic variants in the 3 most common monogenic cerebral small vessel diseases and their associations with prevalent and incident stroke and dementia.
Source: JAMA Neurology - October 27, 2022 Category: Neurology Source Type: research
Error in Text
The Original Investigation “Severity and Etiology of Incident Stroke in Patients Screened for Atrial Fibrillation vs Usual Care and the Impact of Prior Stroke: A Post Hoc Analysis of the LOOP Randomized Clinical Trial,” published online August 29, 2022, had an error in the Statistical Analysis section of the text. The cut off for statistical significance should read P< .05 rather than P> .05. This error has been corrected online.
Source: JAMA Neurology - October 17, 2022 Category: Neurology Source Type: research
Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence
This individual patient data meta-analysis evaluates the association of patent foramen ovale closure on stroke recurrence according to shunt size and/or the presence of an atrial septal aneurysm.
Source: JAMA Neurology - October 10, 2022 Category: Neurology Source Type: research
Broadening Our SCOPE of Understanding Patent Foramen Ovale High-risk Features and Stroke
Paradoxical embolization of a blood clot of presumed venous origin through a patent foramen ovale (PFO) is increasingly recognized as a legitimate cause of otherwise cryptogenic ischemic stroke (CIS). The term PFO-associated stroke has been proposed, as has where and how to classify this entity in the nomenclature of various ischemic stroke subtyping systems. PFOs are common, with prevalence as high as 25% in the general population. The prevalence of PFO is further increased in patients with CIS (overall 2.9 times higher), and especially so in the subset of younger patients (<55 years, 5.1 times higher). One estimate of...
Source: JAMA Neurology - October 10, 2022 Category: Neurology Source Type: research
Association Between ASPECTS and Efficacy and Safety Outcomes With EVT in Patients With Stroke
This secondary analysis of the Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism —Japan Large Ischemic Core Trial (RESCUE-Japan LIMIT) evaluates the safety and efficacy of endovascular therapy in patients with acute large ischemic stroke by Alberta Stroke Program Early Computed Tomography Score.
Source: JAMA Neurology - October 10, 2022 Category: Neurology Source Type: research
General Anesthesia vs Conscious Sedation for EVT in Patients With Posterior Circulation AIS
This exploratory randomized clinical trial evaluates in patients with acute posterior circulation stroke during endovascular treatment with general anesthesia vs conscious sedation.
Source: JAMA Neurology - September 26, 2022 Category: Neurology Source Type: research
Stroke Severity in Atrial Fibrillation Screening
This post hoc analysis of the Atrial Fibrillation Detected by Continuous Electrocardiogram Monitoring Using Implantable Loop Recorder to Prevent Stroke in High-Risk Individuals (LOOP) randomized clinical trial investigates if implantable loop recorder screening for atrial fibrillation can reduce the risk of severe stroke in individuals with risk factors or prior stroke history.
Source: JAMA Neurology - August 29, 2022 Category: Neurology Source Type: research
Diverging Temporal Trends in Stroke Incidence in Younger vs Older People
This systematic review and meta-analysis compares temporal trends in incidence of stroke at younger vs older ages in high-income countries.
Source: JAMA Neurology - August 9, 2022 Category: Neurology Source Type: research
Prevalence of Atherosclerotic Risk Factors Among Children and Young Adults With Arterial Ischemic Stroke
This case-control study assesses hypertension, hyperlipidemia, obesity, smoking, and diabetes as risk factors associated with incident arterial ischemic stroke in children and young adults, stratified by decade of age.
Source: JAMA Neurology - August 1, 2022 Category: Neurology Source Type: research
Time for a New Perspective on Intracerebral Hemorrhage
More than 3 million people worldwide experience intracerebral hemorrhage (ICH) each year. Although the incidence of ICH is much lower than that of ischemic stroke, ICH imposes a 50% greater worldwide burden of disability. ICH has a 30-day case fatality rate of more than 40%, and most survivors are left with permanent disabilities. Because of the high likelihood of poor outcomes, physicians caring for patients with ICH tend to use clinical severity scores early on to estimate the risk of mortality or future disability to determine the aggressiveness of medical care and to guide conversations with patients ’ surrogates aro...
Source: JAMA Neurology - July 25, 2022 Category: Neurology Source Type: research
Outcomes After Endovascular Thrombectomy With or Without Alteplase in Routine Clinical Practice
This cohort study investigates the outcomes of combination endovascular thrombectomy with alteplase compared with endovascular thrombectomy alone for the treatment of patients with acute ischemic stroke attributable to large vessel occlusion.
Source: JAMA Neurology - June 13, 2022 Category: Neurology Source Type: research
