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Promoting Locomotor Learning with Spinal Direct Current Stimulation- Pilot Data (S28.005)
CONCLUSION: After interim analysis, we repowered the study and determined that 14 additional healthy volunteers per group will be needed, to achieve a statistical significance of 97.5 percent and a power of 0.80. Results gathered at this stage will allow us to further assess the effect of tDCS at different stages of locomotor learning, including online, offline, and total learning-- necessary for application in future neurorehabilitation trials involving patients with spinal cord injury and stroke. Study Supported by: Intramural Research Program, NINDSDisclosure: Dr. Awosika has nothing to disclose. Dr. Sandrini has nothin...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Awosika, O., Sandrini, M., Volochayev, R., Xu, B., Floeter, M. K., Hallett, M., Cohen, L. Tags: Neuro-rehabilitation Source Type: research

Neural correlates of action recognition and object knowledge in neurodegenerative disease (P6.196)
CONCLUSIONS: Our results suggest that action recognition is supported by a distributed left lateralized functional network that exhibits dissociable roles. In particular, left mid-posterior temporal and inferior parietal areas seem critical for representation of the gestural component of action recognition while frontal inferior regions may support cognitive control requirements common to all 3 tests.Disclosure: Dr. santos has nothing to disclose. Dr. Illan-Gala has nothing to disclose. Dr. Vinceti has nothing to disclose. Dr. Mandelli has nothing to disclose. Dr. Hubbard has nothing to disclose. Dr. Miller has nothing to ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Santos, M., Illan-Gala, I., Vinceti, G., Mandelli, M. L., Hubbard, H., Miller, Z., Rabinovici, G., Miller, B., Gorno Tempini, M. Tags: Aging, Dementia, Cognitive, and Behavioral Neurology: Neuropsychiatry and Behavioral Neurology Source Type: research

Response to IncobotulinumtoxinA After Resistance to OnabotulinumtoxinA and RimabotulinumtoxinB (P7.061)
CONCLUSIONS:Switching to incobotulinumtoxinA after secondary resistance to onabotulinumtoxinA and rimabotulinumtoxinB may be a viable treatment option in dystonia.Study Supported by:National Institutes of Health- National Institutes of Neurological Diseases and Stroke and the Dystonia Medical Research FoundationDisclosure: Dr. Ramos has received personal compensation for activities with the National Inistitutes of Health as an employee, and the Dystonia Medical Research Foundation. Dr. Karp has nothing to disclose. Dr. Lungu has nothing to disclose. Dr. Alter has nothing to disclose. Dr. Hallett has received personal compe...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramos, V., Karp, B., Lungu, C., Alter, K., Hallett, M. Tags: Movement Disorders: Dystonia Treatment Source Type: research

Tricks to Treatments: Sensory Tricks in Dystonia (P2.042)
CONCLUSIONS:We propose a new classification of ST,to include its variants, such as FT, MT, IT and rST. Wide range of prevalence and effectiveness of ST may reflect ambiguity of terminology and varying measures. More studies are needed to determine the interaction of deep brain stimulation and botulinum toxin with ST. Our research points to more benefit than harm for searching for, or even inducing, ST in patients with dystonia.Study Supported by:National Institutes of Health and the National Institute of Neurological Disorders and Stroke, and the the Dystonia Medical Research Foundation.Disclosure: Dr. Ramos has received p...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramos, V., Karp, B., Hallett, M. Tags: Movement Disorders: Dystonia Source Type: research

High Accordance Rate of Neurologist Referrals for Psychogenic Patients with Expert Opinion at the Movement Disorders Screening Clinic at the Human Motor Control Section of the National Institute of Neurologic Disorders and Stroke (S49.006)
CONCLUSIONS:Neurologist referrals to the Movement Disorders Screening Clinic at the Human Motor Control Section of the National Institute of Neurologic Disorders and Stroke of psychogenic patients have a high accordance rate (94%) with expert opinion from our Institution.Study Supported by:NIH-NINDSDisclosure: Dr. Ramos has received personal compensation for activities with the National Inistitutes of Health as an employee, and the Dystonia Medical Research Foundation. Dr. Villegas has nothing to disclose. Dr. Esquenazi has nothing to disclose. Dr. Hallett has received personal compensation for activities with Neurotoxin I...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramos, V., Villegas, M. A. F., Esquenazi, A., Hallett, M. Tags: Practice, Policy, and Ethics Source Type: research