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Update to the FOCUS, AFFINITY and EFFECTS trials studying the effect(s) of fluoxetine in patients with a recent stroke: statistical analysis plan for the trials and for the individual patient data meta-analysis
Three large trials of fluoxetine for stroke recovery (FOCUS (fluoxetine or control under supervision), AFFINITY (the Assessment oF FluoxetINe In sTroke recovery) and EFFECTS (Efficacy oF Fluoxetine —a randomisE...
Source: Trials - November 25, 2020 Category: General Medicine Authors: Gillian Elizabeth Mead, Catriona Graham, Laurent Billot, Per N äsman, Erik Lundström, Steff Lewis, Graeme J. Hankey, Maree L. Hackett, John Forbes and Martin Dennis Tags: Update Source Type: research

Correction to: Update on the EFFECTS study of fluoxetine for stroke recovery: a randomised controlled trial in Sweden
Following publication of the original article [1], we were notified that one of the corresponding author ’s affiliations was omitted.
Source: Trials - May 7, 2020 Category: General Medicine Authors: Erik Lundstr öm, Eva Isaksson, Per Näsman, Per Wester, Björn Mårtensson, Bo Norrving, Håkan Wallén, Jörgen Borg, Martin Dennis, Gillian Mead, Graeme J. Hankey, Maree L. Hackett and Katharina S. Sunnerhagen Tags: Correction Source Type: research

Update on the EFFECTS study of fluoxetine for stroke recovery: a randomised controlled trial in Sweden
Studies have suggested that fluoxetine might improve neurological recovery after stroke, but the results remain inconclusive. The EFFECTS (Efficacy oF Fluoxetine – a randomisEd Controlled Trial in Stroke) reac...
Source: Trials - February 28, 2020 Category: General Medicine Authors: Erik Lundstr öm, Eva Isaksson, Per Näsman, Per Wester, Björn Mårtensson, Bo Norrving, Håkan Wallén, Jörgen Borg, Martin Dennis, Gillian Mead, Graeme J. Hankey, Maree L. Hackett and Katharina S. Sunnerhagen Tags: Update Source Type: research

The FOCUS, AFFINITY and EFFECTS trials studying the effect(s) of fluoxetine in patients with a recent stroke: a study protocol for three multicentre randomised controlled trials
DiscussionIf fluoxetine is safe and effective in promoting functional recovery, it could be rapidly, widely and affordably implemented in routine clinical practice and reduce the burden of disability due to stroke.Trial registrationFOCUS: ISRCTN83290762 (23/05/2012), AFFINITY: ACTRN12611000774921 (22/07/2011). EFFECTS: ISRCTN13020412 (19/12/2014).
Source: Trials - August 20, 2015 Category: Journals (General) Authors: Gillian MeadMaree HackettErik LundströmVeronica MurrayGraeme HankeyMartin Dennis Source Type: research