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Source: AJP: Regulatory, Integrative and Comparative Physiology
Drug: Inderal

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Total 1 results found since Jan 2013.

Increase in parasympathetic tone by pyridostigmine prevents ventricular dysfunction during the onset of heart failure
Heart failure (HF) is characterized by elevated sympathetic activity and reduced parasympathetic control of the heart. Experimental evidence suggests that the increase in parasympathetic function can be a therapeutic alternative to slow HF evolution. The parasympathetic neurotransmission can be improved by acetylcholinesterase inhibition. We investigated the long-term (4 wk) effects of the acetylcholinesterase inhibitor pyridostigmine on sympathovagal balance, cardiac remodeling, and cardiac function in the onset of HF following myocardial infarction. Myocardial infarction was elicited in adult male Wistar rats. After 4 wk...
Source: AJP: Regulatory, Integrative and Comparative Physiology - October 15, 2013 Category: Physiology Authors: Lataro, R. M., Silva, C. A. A., Fazan, R., Rossi, M. A., Prado, C. M., Godinho, R. O., Salgado, H. C. Tags: Cardiovascular and Renal Integration Source Type: research