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Trends in acute ischemic stroke treatments and mortality in the United States from 2012 to 2018
CONCLUSIONS: From 2012 to 2018, use of tPA and MT increased significantly, irrespective of age, while mortality decreased in the entire AIS population. The most dramatic decrease in mortality was seen in the MT-treated population. Age-standardized mortality improved only in patients older than 70 years, with no change in younger patients.PMID:34198248 | DOI:10.3171/2021.4.FOCUS21117
Source: Neurosurgical Focus - July 1, 2021 Category: Neurosurgery Authors: Sharath Kumar Anand William J Benjamin Arjun Rohit Adapa Jiwon V Park D Andrew Wilkinson Badih J Daou James F Burke Aditya S Pandey Source Type: research

P-029 Impact of in-hospital delirium on outcomes of acute ischemic stroke
ConclusionsDelirium complicates ~3.5% of AIS admissions, and is associated with increased risk of in-hospital death, longer stay, higher charges and decrease in likelihood of home discharge.Disclosures D. Pujara: None. H. Kamal: None. O. Mir: None. S. Reddy: None. K. Parsha: None. S. Patil: None. B. Gogia: None. P. Rai: None. C. Sitton: None. M. Chen: None. M. Abraham: None. M. Hussain: None. A. Hassan: None. A. Sarraj: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Pujara, D., Kamal, H., Mir, O., Reddy, S., Parsha, K., Patil, S., Gogia, B., Rai, P., Sitton, C., Chen, M., Abraham, M., Hussain, M., Hassan, A., Sarraj, A. Tags: Oral poster abstracts Source Type: research

E-111 Repeat thrombectomy after large vessel occlusion stroke: incidence, clinical and technical outcomes
ConclusionsRepeat EVT for patients with re-occlusion within 30 days of thrombectomy is associated with favorable improvement in NIHSS, similar functional outcomes to patients undergoing single EVT, but has significantly higher risk of hemorrhagic conversion.Disclosures Y. Zohdy: None. H. Saad: None. B. Howard: None. C. Cawley: None. A. Pabaney: None. T. Garzon-Muvdi: None. I. Maier: None. A. Spiotta: None. P. Jabbour: None. S. Wolfe: None. A. Rai: None. J. Kim: None. J. Mascitelli: None. R. Starke: None. A. Shaban: None. S. Yoshimura: None. R. De Leacy: None. P. Kan: None. I. Fragata: None. A. Polifka: None. A. Arthur: Non...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Zohdy, Y., Saad, H., Howard, B., Cawley, C., Pabaney, A., Garzon-Muvdi, T., Maier, I., Spiotta, A., Jabbour, P., Wolfe, S., Rai, A., Kim, J., Mascitelli, J., Starke, R., Shaban, A., Yoshimura, S., De Leacy, R., Kan, P., Fragata, I., Polifka, A., Arthur, A Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-185 Study design and rationale of THUNDER: an acute ischemic stroke study with the penumbra system including thunderbolt aspiration tubing
ConclusionWe report the design of THUNDER—a multicenter prospective study that examines the use of a novel modulated aspiration thrombectomy system in patients with AIS secondary to LVO.Disclosures D. Fiorella: 1; C; Cerenovus, Medtronic, Siemens, Stryker, Microvention, Penumbra. 2; C; Balt, Marblehead, Medtronic, Stryker, Microvention, Penumbra, Cerenovus. K. Woodward: 2; C; Coviden. E. Levy: None. C. Matouk: 2; C; Silk Road Medical, Penumbra, MicroVention-TERUMO, Medtronic, Stryker. 3; C; Silk Road Medical, Penumbra. I. Kaminsky: 3; C; Penumbra. K. Reuland: None. M. Stiefel: None. A. Kansagra: 1; C; Penumbra. 2; C;...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Fiorella, D., Woodward, K., Levy, E., Matouk, C., Kaminsky, I., Reuland, K., Stiefel, M., Kansagra, A., Frei, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Effectiveness of Ipsilateral Stroke Prevention Between Conservative Management and Indirect Revascularization for Moyamoya Disease (MMD) in a North American Cohort
This study describes the effectiveness of follow-up stroke prevention by indirect revascularization relative to conservative management in a Northeast United States study population.
Source: World Neurosurgery - November 28, 2017 Category: Neurosurgery Authors: Jose L. Porras, Wuyang Yang, Risheng Xu, Tomas Garzon-Muvdi, Justin M. Caplan, Geoffrey P. Colby, Alexander L. Coon, Edward S. Ahn, Rafael J. Tamargo, Judy Huang Tags: Original article Source Type: research

E-121 Evaluation of safety and efficacy of snuffbox (Distal Radial Artery) access for mechanical thrombectomy in acute ischemic stroke
ConclusionSnuffbox (distal radial artery) access for mechanical thrombectomy in acute ischemic stroke is feasible and safe. It represents a good alternative to the traditional femoral approach, especially in cases of posterior circulation strokes, patients on anticoagulation or with large body habitus.Disclosures A. Kuhn: None. J. Singh: None. F. Massari: None. K. de Macedo Rodrigues: None. V. Naragum: None. V. Anagnostakou: None. M. Gounis: 1; C; National Institutes of Health (NIH), the United States – Israel Binational Science Foundation, Anaconda, ApicBio, Axovant, Cerenovus, Cook Medical, Gentuity, Imperative Car...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Kuhn, A., Singh, J., Massari, F., de Macedo Rodrigues, K., Naragum, V., Anagnostakou, V., Gounis, M., Puri, A. Tags: Electronic poster abstracts Source Type: research

Economic evaluation of intravenous alteplase for stroke with the time of onset between 4.5 and 9 hours
Conclusion For patients with AIS with a time of onset between 4.5 and 9 hours, perfusion imaging-guided intravenous alteplase was likely to be cost-effective in China and was cost-effective in the US when compared with placebo.
Source: Journal of NeuroInterventional Surgery - December 14, 2022 Category: Neurosurgery Authors: Chen, J., Liang, X., Tong, X., Han, M., Ji, L., Zhao, S., Hu, Z., Liu, A. Tags: Open access, Socioeconomics Source Type: research

Unplanned readmission after carotid stenting versus endarterectomy: analysis of the United States Nationwide Readmissions Database
Conclusions Readmission is not uncommon after carotid revascularization, occurs more often after CAS, and is predicted by baseline factors and by preventable adverse events at initial admission.
Source: Journal of NeuroInterventional Surgery - February 14, 2023 Category: Neurosurgery Authors: Nazari, P., Golnari, P., Ansari, S. A., Cantrell, D. R., Potts, M. B., Jahromi, B. S. Tags: Open access, Ischemic stroke Source Type: research

O-001 Trends in endovascular mechanical thrombectomy for acute ischemic stroke: a regional comparison analysis using United States national inpatient sample data
ConclusionsThere remain significant regional differences in the outcomes of EVT for AIS. More analysis is required to determine what is driving these differences. More work is needed to ensure optimal and equitable patient outcomes.Abstract O-001 Table 1 Characteristic (p value) East North Central East South Central Middle Atlantic Mountain New England Pacific South Atlantic West North Central West South Central Age in Years Mean (±SD)(p<0.001) 68.69 ± 14.43 67.04 ± 14.85 70.09 ± 14.39 68.72 ± 14.53 70.27 ± 14.92 70.26 ± 14.51 68.81 ± 14.29 69.21 ± 14.51 67...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brake, A., Fry, L., LeBeau, G., Heskett, C., Lei, C., Alkiswani, A., Le, K., De-Stefano, F., Peterson, J., Ebersole, K. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-010 Racial disparity in mechanical thrombectomy utilization: multicenter registry results from 2016-2020
ConclusionsBlack stroke patients underwent MT less frequently than Whites, likely in part due to longer times from LKW to hospital arrival and a lower rate of documented aLVO. Further studies are needed to assess whether extending the MT time window and more aggressive LVO screening protocols mitigate this disparity.Disclosures A. Wallace: None. D. Gibson: 2; C; iSchemaView, Medtronic, Siemens. K. Asif: None. D. Sahlein: 2; C; Medtronic, Microvention, Stryker, Phenox. 3; C; Medtronic. S. Warach: None. T. Malisch: None. M. Lamonte: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Wallace, A., Gibson, D., Asif, K., Sahlein, D., Warach, S., Malisch, T., Lamonte, M. Tags: Oral abstracts Source Type: research

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