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Source: British Journal of Clinical Pharmacology
Countries: UK Health

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Total 15 results found since Jan 2013.

Comparative safety and effectiveness of direct oral anticoagulants in patients with atrial fibrillation in clinical practice in Scotland
ConclusionsAll DOACs were similarly effective in preventing strokes and systemic embolisms, while patients being treated with rivaroxaban exhibited the highest bleeding risks. Observed differences in the risks of all ‐cause mortality, myocardial infarction, and pulmonary embolism warrant further research.
Source: British Journal of Clinical Pharmacology - November 13, 2018 Category: Drugs & Pharmacology Authors: Tanja Mueller, Samantha Alvarez ‐Madrazo, Chris Robertson, Olivia Wu, Marion Bennie Tags: ORIGINAL ARTICLE Source Type: research

Effectiveness and safety of 110 or 150 mg dabigatran versus vitamin K antagonists in non ‐valvular atrial fibrillation.
ConclusionIn real life D110 and D150 were at least as effective and safer than VKA.
Source: British Journal of Clinical Pharmacology - November 13, 2018 Category: Drugs & Pharmacology Authors: Patrick Blin, Caroline Dureau ‐Pournin, Yves Cottin, Jacques Bénichou, Patrick Mismetti, Abdelilah Abouelfath, Regis Lassalle, Cécile Droz, Nicholas Moore Tags: ORIGINAL ARTICLE Source Type: research

Impact of hydration status on haemodynamics, effects of acute blood pressure ‐lowering treatment, and prognosis after stroke
British Journal of Clinical Pharmacology, EarlyView.
Source: British Journal of Clinical Pharmacology - October 11, 2018 Category: Drugs & Pharmacology Authors: Charlotte K. Billington, Jason P. Appleton, Eivind Berge, Nikola Sprigg, Mark Glover, Philip M. W. Bath Source Type: research

Impact of hydration status on haemodynamics, effects of acute blood pressure lowering treatment, and prognosis after stroke
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-.
Source: British Journal of Clinical Pharmacology - September 8, 2018 Category: Drugs & Pharmacology Authors: Charlotte K.Billington , Jason P.Appleton , EivindBerge , NikolaSprigg , MarkGlover , Philip M.W.Bath Source Type: research

Model ‐based assessment of the benefits and risks of recombinant tissue plasminogen activator treatment in acute ischaemic stroke
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-.
Source: British Journal of Clinical Pharmacology - July 13, 2018 Category: Drugs & Pharmacology Authors: JinjuGuk , DongwooChae , HankilSon , JoonsangYoo , Ji HoeHeo , KyungsooPark Source Type: research

Comparative cardiovascular safety of nonsteroidal anti ‐inflammatory drugs in patients with hypertension: a population‐based cohort study
ConclusionsOur results provide important information about the comparative cardiovascular safety of NSAIDs in patients with hypertension.
Source: British Journal of Clinical Pharmacology - March 13, 2018 Category: Drugs & Pharmacology Authors: Yaa ‐Hui Dong, Chia‐Hsuin Chang, Li‐Chiu Wu, Jing‐Shiang Hwang, Sengwee Toh Tags: DRUG SAFETY Source Type: research

Comparative cardiovascular safety of non ‐steroidal anti‐inflammatory drugs in patients with hypertension: a population‐based cohort study
ConclusionsOur results provide important information about the comparative cardiovascular safety of NSAIDs in patients with hypertension.
Source: British Journal of Clinical Pharmacology - February 22, 2018 Category: Drugs & Pharmacology Authors: Yaa ‐Hui Dong, Chia‐Hsuin Chang, Li‐Chiu Wu, Jing‐Shiang Hwang, Sengwee Toh Tags: DRUG SAFETY Source Type: research

Use of oral anticoagulants in German nursing home residents: drug use patterns and predictors for treatment choice
ConclusionsNOACs are increasingly used in German nursing homes, both for initial anticoagulation but also in VKA pre‐treated patients. Switching from VKA to NOAC was substantially influenced by aspects such as intended higher effectiveness and safety but probably also practicability due to less blood monitoring.
Source: British Journal of Clinical Pharmacology - January 11, 2018 Category: Drugs & Pharmacology Authors: Kathrin Jobski, Falk Hoffmann, Stefan Herget ‐Rosenthal, Michael Dörks Tags: PHARMACOEPIDEMIOLOGY Source Type: research

Cardiac output changes after osmotic therapy in neurosurgical and neurocritical care patients: A systematic review of the clinical literature
ConclusionsMannitol or HTS administration seems to induce an enhancement of cardiac performance; being more prominent after HTS infusion. This effect combined with mannitol‐induced enhancement of diuresis and HTS‐promoted increase of plasma sodium concentration could partially explain the effects of osmotherapy on cerebral hemodynamics.
Source: British Journal of Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Georgia Tsaousi, Elisabetta Stazi, Marco Cinicola, Federico Bilotta Tags: SYSTEMATIC REVIEW AND META ‐ANALYSIS Source Type: research

Oral Anticoagulants in German nursing home residents – Drug use patterns and predictors for treatment choice
ConclusionsNOACs are increasingly used in German nursing homes, both for initial anticoagulation but also in VKA pre‐treated patients. Switching from VKA to NOAC was substantially influenced by aspects such as intended higher effectiveness and safety but probably also practicability due to less blood monitoring.
Source: British Journal of Clinical Pharmacology - November 1, 2017 Category: Drugs & Pharmacology Authors: Kathrin Jobski, Falk Hoffmann, Stefan Herget ‐Rosenthal, Michael Dörks Tags: PHARMACOEPIDEMIOLOGY Source Type: research