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Genetic polymorphisms of T-1131C APOA5 and ALOX5AP SG13S114 with the susceptibility of ischaemic stroke in Morocco.
Abstract Ischaemic stroke is a multifactorial disease. Genetic polymorphisms involved in lipid, inflammatory and thrombotic metabolisms play an important role in the development of ischaemic stroke. The present study aimed to assess the relationship between T1131C APOA5 and SG13S114 ALOX5AP polymorphisms and the risk of ischemic stroke in 175 cases and 201 controls. Genotyping was performed by high resolution melting and polymerase chain reaction restriction fragment length polymorphism methods. In the case of T-1131C APOA5, a modest risk of ischaemic stroke was noticed with CC (OR: 2.86; 95% CI = 1.24-6.58; Pc = ...
Source: Journal of Genetics - May 31, 2016 Category: Genetics & Stem Cells Authors: Diakite B, Hamzi K, Hmimech W, Nadifi S, GMRAVC Tags: J Genet Source Type: research

First study of C2491T FV mutation with ischaemic stroke risk in Morocco.
PMID: 26174681 [PubMed - in process]
Source: Journal of Genetics - June 1, 2015 Category: Genetics & Stem Cells Authors: Diakite B, Hamzi K, Hmimech W, Nadifi S, GMRAVC Tags: J Genet Source Type: research