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Source: The American Journal of Cardiology
Condition: Atrial Fibrillation
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Total 336 results found since Jan 2013.
Comparison of Characteristics and Outcomes of Versus in Hypertensive Patients With Atrial Fibrillation (from the RE-LY Trial)
Hypertension is frequent in patients with atrial fibrillation (AF) and is an independent risk factor for stroke. The Randomized Evaluation of Long Term Anticoagulant TherapY (RE-LY) trial found dabigatran 110 mg (D110) and 150 mg twice daily (D150) noninferior or superior to warfarin for stroke reduction in patients with AF, with either a reduction (D110) or similar rates (D150) of major bleeding. Baseline characteristics and outcomes were compared in patients with and without hypertension. The quality of blood pressure control was also assessed.
Source: The American Journal of Cardiology - July 28, 2015 Category: Cardiology Authors: Rangadham Nagarakanti, Lars Wallentin, Herbert Noack, Martina Brueckmann, Paul Reilly, Andreas Clemens, Stuart J. Connolly, Salim Yusuf, Michael D. Ezekowitz Tags: Arrhythmias and Conduction Disturbances Source Type: research
A Comparison of Atrial Fibrillation Monitoring Strategies After Cryptogenic Stroke (from the Cryptogenic Stroke and Underlying AF Trial)
Ischemic stroke cause remains undetermined in 30% of cases, leading to a diagnosis of cryptogenic stroke. Paroxysmal atrial fibrillation (AF) is a major cause of ischemic stroke but may go undetected with short periods of ECG monitoring. The Cryptogenic Stroke and Underlying Atrial Fibrillation trial (CRYSTAL AF) demonstrated that long-term electrocardiographic monitoring with insertable cardiac monitors (ICM) is superior to conventional follow-up in detecting AF in the population with cryptogenic stroke.
Source: The American Journal of Cardiology - June 24, 2015 Category: Cardiology Authors: William C. Choe, Rod S. Passman, Johannes Brachmann, Carlos A. Morillo, Tommaso Sanna, Richard A. Bernstein, Vincenzo Di Lazzaro, Hans-Christoph Diener, Marilyn M. Rymer, Frank Beckers, Jodi Koehler, Paul D. Ziegler, CRYSTAL AF Investigators Tags: Arrhythmias and Conduction Disturbances Source Type: research
A Comparison of Atrial Fibrillation Monitoring Strategies after Cryptogenic Stroke (From the CRYSTAL AF Trial)
Ischemic stroke etiology remains undetermined in 30% of cases, leading to a diagnosis of cryptogenic stroke. Paroxysmal atrial fibrillation (AF) is a major cause of ischemic stroke but may go undetected with short periods of ECG monitoring. The Cryptogenic Stroke and Underlying Atrial Fibrillation trial (CRYSTAL AF) demonstrated that long-term ECG monitoring with insertable cardiac monitors (ICM) is superior to conventional follow-up in detecting AF in the cryptogenic stroke population. We evaluated the sensitivity and negative predictive value (NPV) of various external monitoring techniques within a cryptogenic stroke cohort.
Source: The American Journal of Cardiology - June 24, 2015 Category: Cardiology Authors: William C. Choe, Rod S. Passman, Johannes Brachmann, Carlos A. Morillo, Tommaso Sanna, Richard Bernstein, Vincenzo Di Lazzaro, Hans-Christoph Diener, Marilyn Rymer, Frank Beckers, Jodi Koehler, Paul D. Ziegler, CRYSTAL AF Investigators Source Type: research
Meta-analysis of CHADS Score in Predicting Atrial Fibrillation
The CHADS2 score is a validated clinical tool used for the risk stratification of stroke in the presence of atrial fibrillation (AF). Recently, some studies have shown that CHADS2 score may predict the risk of AF, which yielded conflicting results. The purpose of this study is to perform a meta-analysis of observational studies to examine the association between the CHADS2 score and risk of AF. Using PubMed and EMBASE database, we searched published articles to November 2014 to identify studies which evaluated the association between CHADS2 score and the risk of AF.
Source: The American Journal of Cardiology - May 20, 2015 Category: Cardiology Authors: Yajuan Yang, Zhiwei Zhang, Chee Yuan Ng, Guangping Li, Tong Liu Source Type: research
Problems in addition to stroke and bleeding after left atrial appendage closure
We read the article by Waksman et al. about the discussions between the US Food and Drug Administration (FDA) and the sponsor regarding approval of the WATCHMAN-device for interventional left atrial appendage closure (LAAC).[1] We would like to stimulate the discussion by the following contribution: LAAC is primarily intended as an alternative for stroke prevention in patients with atrial fibrillation (AF) in whom oral anticoagulation (OAC) is not possible because of contraindications about a high bleeding risk.
Source: The American Journal of Cardiology - April 24, 2015 Category: Cardiology Authors: Claudia Stöllberger, Josef Finsterer, Birke Schneider Source Type: research
Reply
We appreciate the interest in our article, “Overview of the Food and Drug Administration Circulatory System Devices Panel Meetings on WATCHMAN Left Atrial Appendage Closure Therapy,” and that it stimulated provocative discussion in a letter to the editor. First, the WATCHMAN device was approved with the indication to reduce the risk of thromboembolism from the left atrial appendage (LAA) in patients with non-valvular atrial fibrillation, who are at an increased risk for stroke and systemic embolism based on CHADS2 or CHA2DS2-VASc scores; are deemed by their physicians to be suitable for warfarin; and have an appropriat...
Source: The American Journal of Cardiology - April 23, 2015 Category: Cardiology Authors: Ron Waksman Source Type: research
Effect of Race on Outcomes (Stroke and Death) in Patients >65 Years With Atrial Fibrillation
Atrial fibrillation (AF) is associated with stroke and death. We sought to determine whether there are any racial differences in the outcomes of death and stroke in patients with AF. We used Medicare administrative data from January 1, 2010, to December 31, 2011, to identify 517,941 patients with newly diagnosed AF. Of these, 452,986 patients (87%) were non-Hispanic white, 36,425 (7%) were black, and 28,530 (6%) were Hispanic. The association between race and outcomes of death and stroke were measured using Cox proportional hazard models.
Source: The American Journal of Cardiology - April 16, 2015 Category: Cardiology Authors: Rajesh Kabra, Peter Cram, Saket Girotra, Mary Vaughan Sarrazin Tags: Arrhythmias and Conduction Disturbances Source Type: research
Effect of Race on Outcomes (Stroke and Death) in patients > 65 Years of Age with Atrial Fibrillation
Atrial fibrillation (AF) is associated with stroke and death. We sought to determine whether there are any racial differences in the outcomes of death and stroke in patients with AF. We used Medicare administrative data from January 1, 2010 to December 31, 2011 to identify 517,941 patients with newly diagnosed AF. Of these, 452,986 patients (87%) were non-Hispanic white, 36,425 (7%) were black and 28,530 (6%) were Hispanic. The association between race and outcomes of death and stroke were measured using Cox proportional hazard models.
Source: The American Journal of Cardiology - April 16, 2015 Category: Cardiology Authors: Rajesh Kabra, Peter Cram, Saket Girotra, Mary Vaughan Sarrazin Source Type: research
Balancing the Risk of Bleeding and Stroke in Patients with Atrial Fibrillation after Percutaneous Coronary Intervention (from the AVIATOR-registry)
We describe patterns and determinants of antithrombotic prescriptions in this population. The AVIATOR (Antithrombotic strategy Variability In ATrial fibrillation and Obstructive coronary disease Revascularized with PCI) Registry was an international observational study of 859 consecutive patients with AF undergoing PCI between 2009 and 2011.
Source: The American Journal of Cardiology - April 7, 2015 Category: Cardiology Authors: Marco G. Mennuni, Jonathan L. Halperin, Sameer Bansilal, Mikkel M. Schoos, Kleanthis N. Theodoropoulos, Omar A. Meelu, Samantha Sartori, Daniele Giacoppo, Chiara Bernelli, Pedro R. Moreno, Prakash Krishnan, Usman Baber, Carla Lucarelli, George D. Dangas, Source Type: research
Balancing the Risk of Bleeding and Stroke in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention (from the AVIATOR Registry)
We describe patterns and determinants of antithrombotic prescriptions in this population. The Antithrombotic Strategy Variability in Atrial Fibrillation and Obstructive Coronary Disease Revascularized with PCI Registry was an international observational study of 859 consecutive patients with AF who underwent PCI from 2009 to 2011.
Source: The American Journal of Cardiology - April 7, 2015 Category: Cardiology Authors: Marco G. Mennuni, Jonathan L. Halperin, Sameer Bansilal, Mikkel M. Schoos, Kleanthis N. Theodoropoulos, Omar A. Meelu, Samantha Sartori, Daniele Giacoppo, Chiara Bernelli, Pedro R. Moreno, Prakash Krishnan, Usman Baber, Carla Lucarelli, George D. Dangas, Tags: Coronary Artery Disease Source Type: research
Relation between Dabigatran Concentration, as Assessed Using the Direct Thrombin Inhibitor Assay, and Activated Clotting Time/Activated Partial Thromboplastin Time in Patients with Atrial Fibrillation
In this study, we aimed to assess the associations between the dabigatran concentration (calculated via plasma-diluted thrombin time, as assessed using the Hemoclot® assay) and the activated partial thromboplastin time (aPTT) and activated clotting time (ACT). We recruited 137 patients with atrial fibrillation who were receiving a normal dose of dabigatran (300 mg/day) or a reduced dose of dabigatran (220 mg/day, usually administered to patients who were elderly, had moderate renal dysfunction, or who were also receiving verapamil).
Source: The American Journal of Cardiology - March 25, 2015 Category: Cardiology Authors: Kenji Okubo, Taishi Kuwahara, Katsumasa Takagi, Masateru Takigawa, Jun Nakajima, Yuji Watari, Emiko Nakashima, Kazuya Yamao, Tadashi Fujino, Hiroyuki Tsutsui, Atsushi Takahashi Source Type: research
OP-045 Sigmoid Septum with Left Ventricular Outflow Tract Obstruction: Is it Just a Heart Aging?
The evaluation of myocardial infarction, stroke and atrial fibrillation incidence among patients with sigmoid septum and left ventricular outflow tract obstruction.
Source: The American Journal of Cardiology - March 12, 2015 Category: Cardiology Authors: Paloma Manea, Gabriela Cascaval Tags: Oral Abstract Source Type: research
OP-137 Does Electrocardiographic Diastolic Index Predict Asymptomatic Atrial Fibrillation in Patients with Dual-chamber Pacemaker?
Asymptomatic atrial fibrillation episodes detected by pacemaker is known to increase the risk of systemic embolism and stroke by 2-3 times in patients with dual-chamber pacemaker. Atrial high-rate episodes presence together with duration of episodes is also an important indicator of adverse events. The studies have shown the relationship between the electrocardiographic diastolic index and the development of diastolic dysfunction. The aim of our study was to show the relationship between the ECG index (Tend-P/[PQxAge]) and atrial fibrillation in patients with dual-chamber pacemaker.
Source: The American Journal of Cardiology - March 12, 2015 Category: Cardiology Authors: Ahmet Ilker Tekkesin, Emrah Bozbeyoglu, Ozlem Yildirimturk, Ceyhan Turkkan, Yasin Cakilli, Ahmet Murat, Mert Ilker Hayiroglu, Ahmet Taha Alper Tags: Oral Abstract Source Type: research
PP-093 P Wave Dispersion is not Related with Systolic Blood Pressure Variability
Systolic Blood pressure variability (SBPV) is a novel indicator of stroke. P wave dispersion (PWD) is a well known parameter obtained from routine ECG, which is an indicator of interatrial and intraatrial conduction abnormalities. Higher PWD values is linked to higher risk of atrial fibrillation in many prospective studies. The aim of our study is to measure PWD from routine ECG tests of hypertensive patients and to determine its relation with SBPV.
Source: The American Journal of Cardiology - March 12, 2015 Category: Cardiology Authors: Muhammed Necati Murat Aksoy, Harun Kilic, Mehmet Bulent Vatan, Direnc Yilmaz, Ramazan Akdemir, Huseyin Gunduz Tags: Poster Abstract Source Type: research
PP-096 A Newly Defined CHA2DS2-VASc-CAC Score and Using Prediction of Coronary Artery Disease Severity by Computed Tomography
CHA2DS2-VASc scores are validated tools for assessing stroke risk in patients with atrial fibrillation (AF). It is known that traditional risk factors for coronary artery disease and CHAD2 VASc score's parameters are similar.We formulated the CHA2DS2-VASc-CAC score comprising coronary calcium score(CACS) in addition to the components of the CHA2DS2-VASc score and male instead of female gender as We evaluated multivariable risk assessment tools to identify those at high risk of severe CAD in patients who underwent computed tomography(CT).
Source: The American Journal of Cardiology - March 12, 2015 Category: Cardiology Authors: Bora Demircelik, Mahmut Gunes, Muhammed Kemal Yahyalar, Meltem Altinsoy, Fadime Bozduman, Ozgul Malcok Gurel, Beyhan Eryonucu Tags: Poster Abstract Source Type: research
