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Pulmonary Embolism
Venous thromboembolism (VTE) includes pulmonary embolism (PE) and deep vein thrombosis. PE is the third most common cause of cardiovascular death worldwide after stroke and heart attack. Management of PE has evolved recently with the availability of local thrombolysis; mechanical extraction devices; hemodynamic support devices, like extracorporeal membrane oxygenation; and surgical embolectomy. There has been development of multidisciplinary PE response teams nationwide to optimize the care of patients with VTE. This review describes the epidemiology of PE, discusses diagnostic strategies and current and emerging treatment...
Source: Medical Clinics of North America - April 5, 2019 Category: Primary Care Authors: Eno-Obong Essien, Parth Rali, Stephen C. Mathai Source Type: research

Pharmacologic Therapies in Anticoagulation
This article reviews the pharmacology of the main anticoagulant classes (vitamin K antagonists, direct oral anticoagulants, and heparins) and their clinical indications based on evidence-based data currently available in the literature.
Source: Medical Clinics of North America - May 26, 2016 Category: Primary Care Authors: Joana Lima Ferreira, Joyce E. Wipf Source Type: research