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Oral Anticoagulation and Antiplatelets in Atrial Fibrillation Patients After Myocardial Infarction and Coronary Intervention
ConclusionsIn real-life AF patients with indication for multiple antithrombotic drugs after MI/PCI, OAC and clopidogrel was equal or better on both benefit and safety outcomes compared to triple therapy.
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - September 3, 2013 Category: Radiology Source Type: research

Ticagrelor Effects on Myocardial Infarction and the Impact of Event Adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) Trial
ConclusionsIn patients with ACS, ticagrelor significantly reduced the incidence of MI compared with clopidogrel, with consistent results across most MI subtypes. CEC procedures identified more MI endpoints compared with site investigators. (A Comparison of Ticagrelor [AZD6140] and Clopidogrel in Patients With Acute Coronary Syndrome [PLATO]; NCT00391872)
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - April 14, 2014 Category: Radiology Source Type: research

Triple Therapy…Can We Replace More With Better? ∗
Triple therapy, or the use of oral anticoagulation (OAC) in addition to dual antiplatelet therapy (DAPT), is common among patients who have undergone percutaneous coronary intervention (PCI) and have concurrent indications for anticoagulation, such as atrial fibrillation (AF) or mechanical valve replacements. Patients are started on this therapy because of a concern for thrombotic events such as myocardial infarction, stent thrombosis, or embolic stroke. Unfortunately, this potent antithrombotic regimen also exposes patients to increased bleeding. While clinicians were quick to grasp the dangers of thrombotic events, only ...
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - August 3, 2015 Category: Radiology Source Type: research