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Endovascular Thrombectomy of Calcified Emboli in Acute Ischemic Stroke: A Multicenter Study INTERVENTIONAL
CONCLUSIONS: Acute ischemic stroke with large-vessel occlusion due to calcified emboli is a rare entity in patients undergoing thrombectomy, with considerably worse angiographic outcome and a higher mortality compared with patients with noncalcified thrombi. Good functional recovery at 3 months can still be achieved in about a quarter of patients.
Source: American Journal of Neuroradiology - March 16, 2020 Category: Radiology Authors: Maurer, C. J., Dobrocky, T., Joachimski, F., Neuberger, U., Demerath, T., Brehm, A., Cianfoni, A., Gory, B., Berlis, A., Gralla, J., Möhlenbruch, M. A., Blackham, K. A., Psychogios, M. N., Zickler, P., Fischer, S. Tags: INTERVENTIONAL Source Type: research

White Matter Disease and Outcomes of Mechanical Thrombectomy for Acute Ischemic Stroke INTERVENTIONAL
CONCLUSIONS: Moderate-to-severe white matter disease is associated with worse outcomes in patients undergoing endovascular treatment without a significant increase in hemorrhagic complications. Studies comparing patients with and without endovascular treatment are necessary to determine whether the benefit of endovascular treatment is attenuated with greater white matter disease.
Source: American Journal of Neuroradiology - April 8, 2020 Category: Radiology Authors: Mistry, E. A., Mistry, A. M., Mehta, T., Arora, N., Starosciak, A. K., La Rosa, F. D. L. R., Siegler, J. E., Kasner, S. E., Chitale, R., Fusco, M., Froehler, M., Yaghi, S., Schrag, M., Khatri, P., on behalf of BEST Collaborators Tags: INTERVENTIONAL Source Type: research

Location of the Clot and Outcome of Perfusion Defects in Acute Anterior Circulation Stroke Treated with Intravenous Thrombolysis BRAIN
CONCLUSIONS: Admission CBV defects are larger in proximal vessel occlusions. More of the penumbra can be salvaged if the occlusion is located distally. This effect seems to reach a plateau in the distal M1 segment of the MCA.
Source: American Journal of Neuroradiology - January 11, 2013 Category: Radiology Authors: Sillanpaa, N., Saarinen, J. T., Rusanen, H., Elovaara, I., Dastidar, P., Soimakallio, S. Tags: BRAIN Source Type: research

Experimental Evaluation of Immediate Recanalization Effect and Recanalization Efficacy of a New Thrombus Retriever for Acute Stroke Treatment In Vivo INTERVENTIONAL
CONCLUSIONS: In this experimental study, the pREset thrombus retriever showed a high recanalization rate in vivo. High-resolution FPCT allows detailed illustration of the thrombus-device interaction during embedding time and is advocated as an add-on tool to the animal model used in this study.
Source: American Journal of Neuroradiology - January 11, 2013 Category: Radiology Authors: Mordasini, P., Brekenfeld, C., Byrne, J. V., Fischer, U., Arnold, M., Jung, S., Schroth, G., Gralla, J. Tags: INTERVENTIONAL Source Type: research

Pretreatment Advanced Imaging in Patients with Stroke Treated with IV Thrombolysis: Evaluation of a Multihospital Data Base BRAIN
CONCLUSIONS: Use of advanced imaging is increasing in patients treated with IV thrombolysis. While there were differences in outcomes among imaging groups, the clinical effect of advanced imaging remains unclear.
Source: American Journal of Neuroradiology - March 13, 2014 Category: Radiology Authors: McDonald, J. S., Fan, J., Kallmes, D. F., Cloft, H. J. Tags: BRAIN Source Type: research

Whole-Brain Susceptibility-Weighted Thrombus Imaging in Stroke: Fragmented Thrombi Predict Worse Outcome ADULT BRAIN
CONCLUSIONS: Patients with multiple intracranial thrombus fragments constitute a small subgroup of patients with stroke with a worse outcome than patients with single thrombi.
Source: American Journal of Neuroradiology - July 15, 2015 Category: Radiology Authors: Gratz, P. P., Schroth, G., Gralla, J., Mattle, H. P., Fischer, U., Jung, S., Mordasini, P., Hsieh, K., Verma, R. K., Weisstanner, C., El-Koussy, M. Tags: ADULT BRAIN Source Type: research

Endovascular Recanalization in Acute Ischemic Stroke Using the Solitaire FR Revascularization Device with Adjunctive C-Arm CT Imaging INTERVENTIONAL
SUMMARY: In this clinical report, we examined a single-center experience by using the Solitaire FR Revascularization Device in the treatment of acute ischemic stroke in which there was poor initial visualization of the occluded arterial branches by using biplanar cerebral angiography. In all cases, adjunctive C-arm CT was used during the deployment of the thrombectomy device to gain additional information regarding device placement and expansion. Outcome measures included the extent of reperfusion, posttreatment changes in NIHSS scores, posttreatment TICI scores, cerebral hemorrhage, and survival. Clot removal with success...
Source: American Journal of Neuroradiology - July 15, 2015 Category: Radiology Authors: Mitchell, B. D., Chinnadurai, P., Chintalapani, G., Morsi, H. A., Shaltoni, H., Mawad, M. E. Tags: INTERVENTIONAL Source Type: research

Residual Thromboembolic Material in Cerebral Arteries after Endovascular Stroke Therapy Can Be Identified by Dual-Energy CT ADULT BRAIN
CONCLUSIONS: Dual-energy CT may be valuable in the detection of clot persistence or early re-thrombosis without the necessity of additional contrast administration. However, its relevance for the prediction of outcomes remains to be determined in further studies.
Source: American Journal of Neuroradiology - August 13, 2015 Category: Radiology Authors: Grams, A. E., Knoflach, M., Rehwald, R., Willeit, J., Sojer, M., Gizewski, E. R., Glodny, B. Tags: ADULT BRAIN Source Type: research

Focal Low and Global High Permeability Predict the Possibility, Risk, and Location of Hemorrhagic Transformation following Intra-Arterial Thrombolysis Therapy in Acute Stroke INTERVENTIONAL
CONCLUSIONS: Global high Ktrans values can predict the likelihood of hemorrhagic transformation or symptomatic intracranial hemorrhage at the patient level, whereas focal low Ktrans values can predict the spatial distributions of hemorrhagic transformation at the region level.
Source: American Journal of Neuroradiology - September 8, 2017 Category: Radiology Authors: Li, Y., Xia, Y., Chen, H., Liu, N., Jackson, A., Wintermark, M., Zhang, Y., Hu, J., Wu, B., Zhang, W., Tu, J., Su, Z., Zhu, G. Tags: INTERVENTIONAL Source Type: research

Value of Thrombus CT Characteristics in Patients with Acute Ischemic Stroke ADULT BRAIN
CONCLUSIONS: In our study on patients with large-vessel occlusion of the anterior circulation, CT thrombus characteristics appear useful for predicting functional outcome. However, in our study cohort, the effect of intra-arterial treatment was independent of the thrombus CT characteristics. Therefore, no arguments were provided to select patients for intra-arterial treatment using thrombus CT characteristics.
Source: American Journal of Neuroradiology - September 8, 2017 Category: Radiology Authors: Borst, J., Berkhemer, O. A., Santos, E. M. M., Yoo, A. J., den Blanken, M., Roos, Y. B. W. E. M., van Bavel, E., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Marquering, H. A., Majoie, C. B. L. M., on behal Tags: ADULT BRAIN Source Type: research

Radiomics-Based Intracranial Thrombus Features on CT and CTA Predict Recanalization with Intravenous Alteplase in Patients with Acute Ischemic Stroke FUNCTIONAL
CONCLUSIONS: Thrombus radiomics features derived from NCCT and CTA are more predictive of recanalization with IV alteplase in patients with acute ischemic stroke with proximal occlusion than previously known thrombus imaging features such as length, volume, and permeability.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Qiu, W., Kuang, H., Nair, J., Assis, Z., Najm, M., McDougall, C., McDougall, B., Chung, K., Wilson, A. T., Goyal, M., Hill, M. D., Demchuk, A. M., Menon, B. K. Tags: FUNCTIONAL Source Type: research

COVID-19-Associated Carotid Atherothrombosis and Stroke EXTRACRANIAL VASCULAR
We present a radiology-pathology case series of 3 patients with coronavirus disease 2019 (COVID-19) with acute ischemic stroke due to fulminant carotid thrombosis overlying mild atherosclerotic plaque and propose a novel stroke mechanism: COVID-associated carotid atherothrombosis.
Source: American Journal of Neuroradiology - November 11, 2020 Category: Radiology Authors: Esenwa, C., Cheng, N. T., Lipsitz, E., Hsu, K., Zampolin, R., Gersten, A., Antoniello, D., Soetanto, A., Kirchoff, K., Liberman, A., Mabie, P., Nisar, T., Rahimian, D., Brook, A., Lee, S.- K., Haranhalli, N., Altschul, D., Labovitz, D. Tags: EXTRACRANIAL VASCULAR Source Type: research

Perinatal Arterial Ischemic Stroke in Fetal Vascular Malperfusion: A Case Series and Literature Review PEDIATRICS
SUMMARY: Fetal vascular malperfusion includes a continuum of placental histologic abnormalities increasingly associated with perinatal brain injury, namely arterial ischemic stroke. Here, we describe the clinical-neuroimaging features of 5 neonates with arterial ischemic stroke and histologically proved fetal vascular malperfusion. All infarcts involved the anterior territories and were multiple in 2 patients. In 2 neonates, there were additional signs of marked dural sinus congestion, thrombosis, or both. A mixed pattern of chronic hypoxic-ischemic encephalopathy and acute infarcts was noted in 1 patient at birth. Systemi...
Source: American Journal of Neuroradiology - December 11, 2020 Category: Radiology Authors: Geraldo, A. F., Parodi, A., Bertamino, M., Buffelli, F., Uccella, S., Tortora, D., Moretti, P., Ramenghi, L., Fulcheri, E., Rossi, A., Severino, M. Tags: PEDIATRICS Source Type: research

Clot Burden Score and Collateral Status and Their Impact on Functional Outcome in Acute Ischemic Stroke ADULT BRAIN
CONCLUSIONS: The association between the clot burden score and functional outcome varied for different collateral scores. The FLAIR vascular hyperintensity score might be a valuable prognostic factor, especially when contrast-based vascular imaging is not available.
Source: American Journal of Neuroradiology - January 11, 2021 Category: Radiology Authors: Derraz, I., Pou, M., Labreuche, J., Legrand, L., Soize, S., Tisserand, M., Rosso, C., Piotin, M., Boulouis, G., Oppenheim, C., Naggara, O., Bracard, S., Clarencon, F., Lapergue, B., Bourcier,, R., on behalf of the ASTER and the THRACE Trials Investigators Tags: ADULT BRAIN Source Type: research

Risks of Undersizing Stent Retriever Length Relative to Thrombus Length in Patients with Acute Ischemic Stroke INTERVENTIONAL
CONCLUSIONS: Information about thrombus and stent length is more valuable when combined. High thrombus length/stent retriever length ratios, which may raise the risk of unsuccessful recanalization and embolization in new territories, should be avoided by adapting stent retriever selection to thrombus length whenever possible.
Source: American Journal of Neuroradiology - December 13, 2021 Category: Radiology Authors: Belachew, N. F., Dobrocky, T., Meinel, T. R., Hakim, A., Vynckier, J., Arnold, M., Seiffge, D. J., Wiest, R., Piechowiak, E. I., Fischer, U., Gralla, J., Mordasini, P., Kaesmacher, J. Tags: INTERVENTIONAL Source Type: research

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