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Outcomes of primary percutaneous coronary intervention in acute myocardial infarction due to unprotected left main thrombosis: The Asia ‐Pacific Left Main ST‐Elevation Registry (ASTER)
ConclusionsSTEMI from culprit unprotected left main coronary artery stenosis is associated with significant mortality and morbidity. Emergency PCI provides an important treatment option in this high‐risk group, but in‐hospital mortality remains high.
Source: Journal of Interventional Cardiology - November 16, 2017 Category: Cardiology Authors: Jonathan Yap, Gagan D. Singh, Jung ‐Sun Kim, Krishan Soni, Kelvin Chua, Alvin Neo, Choong Hou Koh, Ehrin J. Armstrong, Stephen W. Waldo, Kendrick A. Shunk, Reginald I. Low, Myeong‐Ki Hong, Yangsoo Jang, Khung Keong Yeo Tags: ORIGINAL INVESTIGATION Source Type: research

Head ‐to‐head comparison of prasugrel versus ticagrelor in patients undergoing percutaneous coronary intervention: A meta‐analysis of randomized controlled trials
ConclusionsAlthough the efficacy was similar between prasugrel and ticagrelor, prasugrel may be associated with a lower risk of bleeding compared with ticagrelor during short‐ to mid‐term follow‐up period after PCI. Further studies are warranted in a larger patient population during longer‐term follow up to validate these findings.
Source: Journal of Interventional Cardiology - August 1, 2017 Category: Cardiology Authors: Ryota Sakurai, Ivana Burazor, Heidi N. Bonneau, Hideaki Kaneda Tags: ORIGINAL INVESTIGATION Source Type: research

Age is not a bar to PCI: Insights from the long ‐term outcomes from off‐site PCI in a real‐world setting
ConclusionsThis study demonstrates an acceptable occurrence of MI, death, repeat intervention, and stent thrombosis in a high‐risk group of V. Eld. patients with de novo lesions. Age alone in the absence of other non‐cardiac factors should not prohibit a patient from access to PCI.
Source: Journal of Interventional Cardiology - July 2, 2017 Category: Cardiology Authors: Robert T. Gerber, Satpal S. Arri, Mohamed O. Mohamed, Gurpreet Dhillon, Alykhan Bandali, Idris Harding, Jeremy Gifford, Belinda Sandler, Ben Corbo, Eric McWilliams Tags: ORIGINAL INVESTIGATION Source Type: research

Safety of orbital atherectomy in patients with left ventricular systolic dysfunction
ConclusionPlaque modification with OA was safe and well tolerated in patients with systolic dysfunction. In this high‐risk cohort, adverse clinical outcomes occurred more frequently than in a lower risk population.
Source: Journal of Interventional Cardiology - June 1, 2017 Category: Cardiology Authors: Evan Shlofmitz, Perwaiz Meraj, Rajiv Jauhar, Sanjum S. Sethi, Richard A. Shlofmitz, Michael S. Lee Tags: ORIGINAL INVESTIGATION Source Type: research

Outcomes in Diabetic Patients Undergoing Orbital Atherectomy System
ConclusionDiabetics represented a sizeable portion of patients who underwent orbital atherectomy. Diabetics who had severely calcified coronary arteries and underwent orbital atherectomy had low event rates that were similar to non‐diabetics. Orbital atherectomy appears to be a viable treatment strategy for diabetic patients. Randomized trials with longer‐term follow‐up are needed to determine the ideal treatment strategy for diabetics.
Source: Journal of Interventional Cardiology - July 31, 2016 Category: Cardiology Authors: Michael S. Lee, Evan Shlofmitz, Heajung Nguyen, Richard A. Shlofmitz Tags: Original Investigation Source Type: research

Real ‐World Multicenter Registry of Patients with Severe Coronary Artery Calcification Undergoing Orbital Atherectomy
ConclusionIn the largest real‐world study of patients who underwent orbital atherectomy, including high‐risk patients who were not surgical candidates as well as those with very complex coronary anatomy, acute and short‐term adverse clinical event rates were low. A randomized clinical trial is needed to identify the ideal treatment strategy for patients with severe CAC.
Source: Journal of Interventional Cardiology - June 29, 2016 Category: Cardiology Authors: Michael S. Lee, Evan Shlofmitz, Barry Kaplan, Dragos Alexandru, Perwaiz Meraj, Richard Shlofmitz Tags: Original Investigation Source Type: research

Real‐World Multicenter Registry of Patients with Severe Coronary Artery Calcification Undergoing Orbital Atherectomy
ConclusionIn the largest real‐world study of patients who underwent orbital atherectomy, including high‐risk patients who were not surgical candidates as well as those with very complex coronary anatomy, acute and short‐term adverse clinical event rates were low. A randomized clinical trial is needed to identify the ideal treatment strategy for patients with severe CAC.
Source: Journal of Interventional Cardiology - June 29, 2016 Category: Cardiology Authors: Michael S. Lee, Evan Shlofmitz, Barry Kaplan, Dragos Alexandru, Perwaiz Meraj, Richard Shlofmitz Tags: Original Investigation Source Type: research

Safety and Efficacy of Immediate Rotational Atherectomy in Nondilatable Calcified Coronary Lesions Complicated by Coronary Artery Dissection (RAISE)
ConclusionThis study indicates that immediate RA during PCI is safe and effective in patients with coronary artery dissection. (J Interven Cardiol 2015;28:456–463)
Source: Journal of Interventional Cardiology - October 22, 2015 Category: Cardiology Authors: Dongwei Zhang, Jianqiang Hu, Wanrong Man, Tingting Wang, Mingming Zhang, Jie Lin, Kazim Narsinh, Lei Zhang, Chengxiang Li, Dongdong Sun Tags: Randomized Trial Source Type: research

First‐in‐Man Study of Dedicated Bifurcation Sirolimus‐eluting Stent: 12‐month Results of BiOSS LIM® Registry
ConclusionDedicated bifurcation stent BiOSS® LIM proved to be feasible device, with promising safety and long‐term clinical effectiveness in the treatment of coronary bifurcation lesions, including distal left main stem stenosis. (J Interven Cardiol 2015;28:51–60)
Source: Journal of Interventional Cardiology - February 16, 2015 Category: Cardiology Authors: ROBERT J. GIL, JACEK BIL, DOBRIN VASSILIEV, LUIS A. IÑIGO GARCIA Tags: Original Investigation Source Type: research

Rationale and Design of the On‐Treatment PLAtelet Reactivity‐Guided Therapy Modification FOR ST‐Segment Elevation Myocardial Infarction (PLATFORM) Randomized Trial
ConclusionPLATFORM will determine whether the platelet reactivity‐guided use of ticagrelor in combination with 200 mg aspirin, compared with standard antiplatelet regimen, improves clinical outcome in moderate to high‐risk STEMI patients undergoing PPCI. Clinical Trial RegistrationU.S. National Institutes of Health (NIH) at www.clinicaltrials.gov. ClinicalTrials.gov Identifier: NCT01739556, and Current Controlled Trials at www.controlledtrials.com. International Standard Randomized Controlled Trial Number ISRCTN83081599.
Source: Journal of Interventional Cardiology - December 1, 2012 Category: Cardiology Authors: IGOR MRDOVIC, LIDIJA SAVIC, GORDANA KRLJANAC, MILIKA ASANIN, NATASA CVETINOVIC, NATASA BRDAR, MILENA STOJANOVIC, NEMANJA DJURICIC, SANJA STANKOVIC, JELENA MARINKOVIC, JOVAN PERUNICIC Tags: Randomized Trial Source Type: research