• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

The Implementation of Targeted Temperature Management: An Evidence-Based Guideline from the Neurocritical Care Society
ConclusionThis guideline is intended for neurocritical care clinicians who have chosen to use TTM in patient care; it is not meant to provide guidance regarding the clinical indications for TTM itself. While there are areas of TTM practice where clear evidence guides strong recommendations, many of the recommendations are conditional, and must be contextualized to individual patient and system needs.
Source: Neurocritical Care - October 16, 2017 Category: Neurology Source Type: research

Spontaneous Intracranial Hemorrhage in Pregnancy: A Systematic Review of the Literature
AbstractStroke in pregnant women has a mortality rate of 1.4 deaths per 100,000 deliveries. Vascular malformations are the most common cause of hemorrhagic stroke in this population; preeclampsia and other risk factors have been identified. However, nearly a quarter of strokes have an undeterminable cause. Spontaneous intracranial hemorrhage (ICH) is less frequent but results in significant morbidity. The main objective of this study is to review the literature on pregnant patients who had a spontaneous ICH. A systematic review of the literature was conducted on PubMed and the Cochrane library from January 1992 to Septembe...
Source: Neurocritical Care - February 23, 2018 Category: Neurology Source Type: research

Fever Burden and Health-Related Quality of Life After Intracerebral Hemorrhage
ConclusionsEach additional day with a fever was predictive of worse HRQoL domains of Cognitive Function and Mobility after ICH up to 1  year. These data extend previous evidence on the negative association of fever and functional outcomes to the domains of Cognitive Function and Mobility HRQoL. HRQoL outcomes may be a sensitive and powerful way to measure the efficacy of fever control in future research.
Source: Neurocritical Care - March 29, 2018 Category: Neurology Source Type: research

Cerebrovascular Events After Continuous-Flow Left Ventricular Assist Devices
ConclusionsLVADs are associated with high rates of CVE, increased mortality, and lower rates of heart transplantation. Further investigations to identify the optimal primary and secondary stroke prevention measures in post-LVAD patients are warranted.
Source: Neurocritical Care - April 10, 2018 Category: Neurology Source Type: research

Effects of Diabetes Mellitus and Admission Glucose in Patients Receiving Mechanical Thrombectomy: A Systematic Review and Meta-analysis
ConclusionsThe present study confirms that a history of diabetes mellitus and high AGL are associated with unfavorable functional outcomes at 3  months after MT in AIS patients. However, the causal relationship between hyperglycemia and poor prognosis remains undetermined, and further investigations are required to ascertain whether AIS patients receiving MT could benefit from intensive glucose control.
Source: Neurocritical Care - June 26, 2018 Category: Neurology Source Type: research

The Role of Serum Calcium Level in Intracerebral Hemorrhage Hematoma Expansion: Is There Any?
AbstractSpontaneous intracerebral hemorrhage (ICH) is a devastating form of stroke, with a high rate of mortality and morbidity. Even with the best current medical or surgical interventions, outcomes remain poor. The location and initial hematoma volume are strong predictors of mortality. Hematoma expansion (HE) is a further marker of poor prognosis that may be at least partly preventable. Several risk factors for HE have been identified, including baseline ICH volume, anticoagulation, and computed tomography angiography spot signs. Recent studies have shown the correlation of serum calcium (Ca++) levels on admission with ...
Source: Neurocritical Care - June 27, 2018 Category: Neurology Source Type: research

Long-Term Outcomes in Patients with Anemia And Cerebral Venous Thrombosis
ConclusionsAnemia was a significant and independent predictor of unfavorable functional outcome in patients with CVT.
Source: Neurocritical Care - July 9, 2018 Category: Neurology Source Type: research

The Risk of Takotsubo Cardiomyopathy in Acute Neurological Disease
ConclusionTCM appears to be associated with varying degrees with several acute neurological diseases besides subarachnoid hemorrhage.
Source: Neurocritical Care - August 9, 2018 Category: Neurology Source Type: research

Dehydration Status Predicts Short-Term and Long-Term Outcomes in Patients with Cerebral Venous Thrombosis
ConclusionsThe present findings indicate that dehydration is an independent predictor for short-term and long-term unfavorable functional outcome in patients with CVT.
Source: Neurocritical Care - October 25, 2018 Category: Neurology Source Type: research

External Validation of Hematoma Expansion Scores in Spontaneous Intracerebral Hemorrhage in an Asian Patient Cohort
ConclusionsTo our knowledge, this is the first study to validate HE scores, namely PREDICT, 9-Point and BRAIN, in a multi-ethnic Asian ICH patient population. The PREDICT score was the best performing model in our study cohort, based on the performance metrics employed in this study. Our findings also showed support for CT angiography spot sign as a predictor of outcome after ICH. Although the models assessed are sufficient for risk stratification, the discrimination and calibration are at best moderate and could be improved.
Source: Neurocritical Care - October 30, 2018 Category: Neurology Source Type: research

The Full Outline of UnResponsiveness (FOUR) Score and Its Use in Outcome Prediction: A Scoping Systematic Review of the Adult Literature
ConclusionsThe FOUR score has been shown to be a useful outcome predictor in many patients with depressed level of consciousness. It displays good inter-rater reliability among physicians and nurses.
Source: Neurocritical Care - November 8, 2018 Category: Neurology Source Type: research

Serum Alkaline Phosphatase Level is Associated with Angiographic Vasospasm, Delayed Cerebral Ischemia-Caused Clinical Deterioration, and Functional Outcome After Aneurysmal Subarachnoid Hemorrhage
ConclusionsElevated serum ALP level is associated with vasospasm, DCI-caused clinical deterioration, and functional outcome after aSAH. Further studies are required to examine the potential role of serum ALP as an outcome predictor for aSAH patients.
Source: Neurocritical Care - April 22, 2019 Category: Neurology Source Type: research

Common Data Elements for Unruptured Intracranial Aneurysm and Subarachnoid Hemorrhage Clinical Research: Recommendations from the Working Group on Long-Term Therapies
ConclusionsNoting gaps in the literature regarding medication and rehabilitation parameters in UIA and SAH clinical studies, the current CDE recommendations aim to arouse interest to explore the impact of medication and rehabilitation treatments and therapies and encourage the convergence of LTT clinical study parameters to develop a harmonized standard.
Source: Neurocritical Care - May 9, 2019 Category: Neurology Source Type: research

Evidence for Mannitol as an Effective Agent Against Intracranial Hypertension: An Individual Patient Data Meta-analysis
AbstractMannitol is currently used to reduce intracranial pressure (ICP), but the evidence supporting its usefulness has been questioned. We aim to meta-analyze the effectiveness of mannitol in reducing ICP in adult patients with cerebral injuries and its dependency on baseline ICP values, comparing findings from individual patient data (IPD) and aggregated data (AD) meta-analysis performed on the same studies. We searched the Medline database, with no time limitation, through March 1, 2019. We selected studies for which IPD were available, with a before-after design, concerning adult patients with traumatic cerebral hemor...
Source: Neurocritical Care - June 30, 2019 Category: Neurology Source Type: research

Prolonged Heightened Blood Pressure Following Mechanical Thrombectomy for Acute Stroke is Associated with Worse Outcomes
ConclusionHigh daily maximum SBP and a rebound SBP on the third day following MT is independently associated with increased likelihood of functional dependence.
Source: Neurocritical Care - August 4, 2019 Category: Neurology Source Type: research

Pages: 1  2  3  4  5  6  7  8  9