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Daily multivitamin supplements did not reduce risk for major CV events over > 10 years in men.
CONCLUSION Daily multivitamin supplements did not affect risk for major cardiovascular events over > 10 years in male physicians in the USA.Daily multivitamin supplements vs placebo in male physicians in the USA‡OutcomesMultivitaminPlaceboAt a median 11.2 yRRI (95% CI)§NNHMajor CV events12.0%11.7%1% (-8 to 9)NSFatal and nonfatal stroke4.5%4.2%6% (-9 to 22)NSRRR (CI)§NNTFatal and nonfatal MI4.3%4.6%7% (-9 to 20)NSAll-cause mortality18%19%5% (-2 to 11)NS‡CV = cardiovascular; MI = myocardial infarction; NS = not significant; other abbreviations defined in Glossary. RRI, RRR, and CI calculated from adjusted hazar...
Source: Annals of Internal Medicine - February 19, 2013 Category: Internal Medicine Authors: Fairfield KM Tags: Ann Intern Med Source Type: research
