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The short- and long-term efficacy of intravascular stenting in the treatment of intracranial artery stenosis
CONCLUSION: The short- and long-term efficacy of intravascular stenting in the treatment of intracranial artery stenosis is significant. What's more, a history of coronary heart disease and advanced age (≥70 years) are independent risk factors contributing to postoperative restenosis.PMID:34306471 | PMC:PMC8290700
Source: American Journal of Translational Research - July 26, 2021 Category: Research Authors: Qiang Jia Shixin Yan Source Type: research

Significant role and mechanism of microRNA-143-3p/KLLN axis in the development of coronary heart disease.
In this study, we identified that miR-143-3p was up-regulated in rabbit CHD model. The results of TargetScan and the dual luciferase reporter assay indicated that KLLN (killin, p53 regulated DNA replication inhibitor) was a direct target of miR-143-3p. Besides, we revealed that KLLN was down-regulated in rabbit coronary heart disease model. In addition, we found that the related-markers of CHD such as TC (total cholesterol), TG (triglyceride), and LDLC (low-density lipoprotein cholesterol) in the model group were significantly increased than that in the control group. And compared with the model group, miR-143-3p inhibitor...
Source: American Journal of Translational Research - July 19, 2019 Category: Research Tags: Am J Transl Res Source Type: research

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