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Effect of sildenafil on maternal hemodynamics in pregnancies complicated by severe early-onset fetal growth restriction: planned subgroup analysis from a multicenter randomized placebo-controlled double-blind trial.
CONCLUSIONS: Sildenafil in a dose of 25 mg three times daily increases HR, reduces BP and reduces arterial stiffness in pregnancies complicated by FGR. These changes are modest, consistent with the anticipated vasodilatory effect and their clinical impact on the mother and baby, in both the short- and long-term, remains uncertain. This article is protected by copyright. All rights reserved. PMID: 31432556 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - August 19, 2019 Category: Radiology Authors: Khalil A, Sharp A, Cornforth C, Jackson R, Mousa H, Stock S, Harrold J, Turner MA, Kenny LC, Baker PN, Johnstone ED, von Dadelszen P, Magee L, Papageorghiou AT, Alfirevic Z Tags: Ultrasound Obstet Gynecol Source Type: research

Maternal hemodynamics, fetal biometry and Dopplers in pregnancies followed up for suspected fetal growth restriction.
CONCLUSIONS: In pregnancies with SGA fetuses there is decreased maternal cardiac output and stroke volume and increased peripheral vascular resistance and MAP and the deviations from normal are most marked in cases of redistribution in the fetal circulation and reduced amniotic fluid volume. PMID: 29607557 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - April 1, 2018 Category: Radiology Authors: Roberts LA, Ling HZ, Poon L, Nicolaides KH, Kametas NA Tags: Ultrasound Obstet Gynecol Source Type: research

Longitudinal hemodynamics in acute phase of treatment with labetalol in hypertensive pregnant women to predict need for vasodilatory therapy
ConclusionMaternal demographics and hemodynamic changes in the acute phase of labetalol monotherapy provide a powerful tool to identify hypertensive pregnant patients who are unlikely to have their BP controlled by this therapy and will consequently need additional vasodilatory therapy. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.
Source: Ultrasound in Obstetrics and Gynecology - November 30, 2016 Category: Radiology Authors: D. Stott, M. Bolten, D. Paraschiv, I. Papastefanou, J. B. Chambers, N. A. Kametas Tags: Original Paper Source Type: research