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Source: Neurology
Condition: Heart Attack

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Total 80 results found since Jan 2013.

Association between percent decline in serum total homocysteine and risk of first stroke
Conclusions: Percent lowering in tHcy was significantly associated with a reduction in first stroke risk in Chinese adults with hypertension, and if further confirmed, may serve as a useful indicator for folic acid treatment efficacy on stroke prevention. Clinicaltrials.gov identifier: NCT00794885.
Source: Neurology - November 13, 2017 Category: Neurology Authors: Huang, X., Li, Y., Li, P., Li, J., Bao, H., Zhang, Y., Wang, B., Sun, N., Wang, J., He, M., Yin, D., Tang, G., Chen, Y., Cui, Y., Huang, Y., Hou, F. F., Qin, X., Huo, Y., Cheng, X. Tags: Stroke prevention, All Clinical trials ARTICLE Source Type: research

Smoking cessation and outcome after ischemic stroke or TIA
Conclusion: Cessation of cigarette smoking after an ischemic stroke or TIA was associated with significant health benefits over 4.8 years in the IRIS trial cohort.
Source: Neurology - October 16, 2017 Category: Neurology Authors: Epstein, K. A., Viscoli, C. M., Spence, J. D., Young, L. H., Inzucchi, S. E., Gorman, M., Gerstenhaber, B., Guarino, P. D., Dixit, A., Furie, K. L., Kernan, W. N., For the IRIS Trial Investigators Tags: Stroke prevention, Prognosis, All Cerebrovascular disease/Stroke, Infarction ARTICLE Source Type: research

Long-term Risk of Complications after Percutaneous Transcatheter Closure of Patent Foramen Ovale (S51.003)
Conclusions:Approximately 1 in 6 patients who undergo percutaneous transcatheter closure of PFO after stroke or transient ischemic attack experience a serious complication or death within 5 years.Study Supported by:Dr. Gialdini is supported by the Feil Family Foundation.Dr. Navi is supported by NIH grant K23NS091395 and the Florence Gould Endowment for Discovery in Stroke.Dr. Iadecola is supported by NIH grants R37NS089323-02, R01NS034179-21, R01NS037853-19, and R01 NS073666-04.Dr. Kamel is supported by NIH grants K23NS082367 and R01NS097443 as well as the Michael Goldberg Research Fund.Disclosure: Dr. Merkler has nothing ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Merkler, A., Gialdini, G., Yaghi, S., Okin, P., Iadecola, C., Navi, B., Kamel, H. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke Prevention and Translation Source Type: research

Resumption of Antithrombotic Therapy in LVAD-associated Intracranial Hemorrhages (P2.273)
Conclusions:Among survivors of LVAD-associated ICH, those who resumed both antiplatelet plus warfarin therapy had fewer ischemic, but more hemorrhagic events than those who resumed antiplatelet therapy alone.Disclosure: Dr. Cho has nothing to disclose. Dr. Frontera has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Cho, S.-M., Frontera, J. Tags: Intracerebral Hemorrhage Source Type: research

Acute neurologic complications of cardiac catheterization: clinical syndromes and outcomes (P6.296)
Conclusions:In this study, half of post-LHC neurologic syndromes prompting neurology consultation were cerebrovascular and half were non-cerebrovascular in nature. Hemiparesis was strongly associated with CVD, and positive visual phenomena were strongly associated with migraine aura.Disclosure: Dr. Horn has nothing to disclose. Dr. Selim has nothing to disclose. Dr. Leung has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Horn, S., Selim, M., Leung, L. Tags: Cardiovascular Issues in Ischemic Stroke Source Type: research

Myocardial Wall Rupture Following tPA Administration: A Case Report and Review of the Literature (P3.270)
Conclusions:Although the frequency of pericarditis, mural hemorrhage and subsequent myocardial rupture after MI is declining following PCI, clinicians should be mindful of this potential complication in tPA treated patients with recent MI. Further, cardiac wall rupture should be considered in patients who develop acute hypotension and bradycardia following tPA administration. The current literature is limited and insufficient to provide generalizable guidance on managing AIS patients with recent MI.Disclosure: Dr. Neu has nothing to disclose. Dr. Albright has nothing to disclose. Dr. Lyerly has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Neu, M., Albright, K., Lyerly, M. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Predictive Variables of Cognitive Dysfunction in Patients with Lupus (P1.340)
Conclusions:Duration of disease and low educational level are predictors of CD in patients with SLE. Depression and anxiety did not influence cognitive performance. Although cardiovascular comorbidity is a risk factor for dementia in general population, those variables might play a minor role in SLE patients.Study Supported by:Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and São Paulo Research Foundation (FAPESP) (grant #2015/08833-7) supported this study.Disclosure: Dr. Alessi has nothing to disclose. Dr. Dutra Antonio has nothing to disclose. Dr. Maria has nothing...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Alessi, H., Dutra, L. A., Maria, L., Xavier, P., Couce, P., Kayser, C., Barsottini, O. Tags: CNS Inflammatory Diseases and Differential Diagnosis I Source Type: research

Safety Outcome of Carotid Artery Stenting in Long Carotid Lesion with Proximal versus Distal Embolic Protection Devices (P3.077)
Conclusions:Patients with carotid lesion length >10mm undergoing CAS with PPD shows a trend to better safety outcomes including perioperative stroke than patients with DPD. A larger prospective study is needed to confirm this finding.Disclosure: Dr. Saini has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Goswami has nothing to disclose. Dr. Ambekar has nothing to disclose. Dr. Ramdas has nothing to disclose. Dr. Guada has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Medtronic and Guidepoint as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Saini, V., Atchaneeyasakul, K., Goswami, A., Ambekar, S., Ramdas, K., Guada, L., Yavagal, D. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

A Brief Dementia Screening Test in South Africa: Results from the Health and Aging Longitudinal Study of an INDEPTH community (HAALSI) (P4.191)
Conclusions:There is a potentially protective and long-lasting impact of secondary school education on cognitive status later in life in this setting. Using a brief screening test in this relatively poor cohort of older South Africans, patterns of low cognition are similar to those in the USA and other countries.Study Supported by:The National Institute on Aging at the National Institute of Health (NIH) (1P01AG041710-01A1; 1R01AG051144–01; 3U54HG006938-03S1). F. Mateen is supported by a subgrant of P30AG024409 from the NIH for the Harvard Center for Global Demography and Aging. The Agincourt HDSS was supported by the...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mateen, F., Jennings, E., Montana, L., Wagner, R., Kahn, K., Tollman, S., Berkman, L. Tags: Behavioral and Cognitive Neurology: Neurodegenerative Disorders Source Type: research

Relationship between risk factor control and vascular events in the SAMMPRIS trial
Conclusions: Raised blood pressure, cholesterol, and physical inactivity should be aggressively treated in patients with intracranial atherosclerosis to prevent future vascular events. Physical activity, which has not received attention in stroke prevention trials, was the strongest predictor of a good outcome in the medical arm in SAMMPRIS. ClinicalTrials.gov identifier: NCT00576693.
Source: Neurology - January 22, 2017 Category: Neurology Authors: Turan, T. N., Nizam, A., Lynn, M. J., Egan, B. M., Le, N.-A., Lopes-Virella, M. F., Hermayer, K. L., Harrell, J., Derdeyn, C. P., Fiorella, D., Janis, L. S., Lane, B., Montgomery, J., Chimowitz, M. I. Tags: Stroke prevention, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

IV tPA for acute ischemic stroke: Times are changing
Based on evidence that the administration of IV tissue plasminogen activator (tPA) improved the outcomes of selected patients with acute ischemic stroke, the US Food and Drug Administration (FDA) approved its use for this purpose in 1996, leading to a revolution in stroke care.1 Following its introduction into routine clinical practice, stroke began to be viewed as a medical emergency, similar to myocardial infarction, with effective treatment dependent or early symptom recognition and patient transport to facilities capable of conducting rapid evaluations and IV tPA administration. There were, however, considerable barrie...
Source: Neurology - November 20, 2016 Category: Neurology Authors: Goldstein, L. B. Tags: Medical care, All Cerebrovascular disease/Stroke, All epidemiology EDITORIALS Source Type: research

Von Willebrand Factor and the Risk of Dementia: A Population-Based Study (P1.092)
Conclusions: Higher levels of Von Willebrand factor are associated with an increased risk of dementia, including Alzheimer’s disease, possibly due to direct prothrombotic effects or secondary to endothelial injury.Disclosure: Dr. Wolters has nothing to disclose. Dr. Boender has nothing to disclose. Dr. Hofman has nothing to disclose. Dr. De Maat has nothing to disclose. Dr. Koudstaal has nothing to disclose. Dr. Leebeek has received research support from Baxter and CSL Behring. Dr. Ikram has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Wolters, F., Boender, J., Hofman, A., De Maat, M., Koudstaal, P., Leebeek, F., Ikram, M. Tags: Epidemiology of Aging and Dementias Source Type: research

Smoking is Associated with All-Cause Mortality after Stroke (P1.121)
Conclusions: Stroke survivors who continue to smoke are nearly 2.5 times more likely to die of all causes compared to those who never smoked and nearly twice as likely to die of all causes compared to former smokers. These findings underscore the importance of smoking cessation counseling in order to improve outcomes after stroke.Disclosure: Dr. MacCallum has nothing to disclose. Dr. Lekoubou Looti has nothing to disclose. Dr. Ovbiagele has nothing to disclose. Dr. Markovic has nothing to disclose. Dr. Towfighi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: MacCallum, H., Lekoubou Looti, A., Ovbiagele, B., Markovic, D., Towfighi, A. Tags: Cerebrovascular Disease: Epidemiology Source Type: research

Clopidogrel and Smoking Status Among Ischemic Stroke Patients: Smokers Paradox? (P1.122)
Conclusions: We found that ischemic stroke patients who actively smoked derived a slight yet non statistically significant benefit from clopidogrel compared to aspirin for vascular risk reduction. This issue needs to be further evaluated in additional studies of larger size.Disclosure: Dr. Zhang has nothing to disclose. Dr. Wang has nothing to disclose. Dr. Song has nothing to disclose. Dr. Ji has nothing to disclose. Dr. Hou has nothing to disclose. Dr. Cao has nothing to disclose. Dr. Dong has nothing to disclose. Dr. Huang has nothing to disclose. Dr. Feng has nothing to disclose. Dr. Ovbiagele has nothing to disclose. ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zhang, Q., Wang, Y., Song, H., Ji, X., Hou, C., Cao, Q., Dong, K., Huang, X., Feng, W., Ovbiagele, B., Wang, M. Tags: Cerebrovascular Disease: Epidemiology Source Type: research

Prevalence of Obstructive Sleep Apnea-Hypopnea Syndrome in Patients with Acute Cerebral Infarction (P1.179)
Conclusions: High prevalence of MSOSA was found in our population. Those patients had extended hospital stay, higher BMI and greater weight. Prolonged hospitalization was not related to greater NIHSS. Our results suggest that patients with acute cerebral infarction should be systematically assessed for the presence of OSA.Disclosure: Dr. Quiroga has nothing to disclose. Dr. Berrozpe has nothing to disclose. Dr. Chertcoff has nothing to disclose. Dr. Pantiu has nothing to disclose. Dr. Pacha has nothing to disclose. Dr. Leon Cejas has nothing to disclose. Dr. Martinez has nothing to disclose. Dr. Bonardo has nothing to disc...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Quiroga, J., Berrozpe, C., Chertcoff, A., Pantiu, F., Pacha, S., Leon Cejas, L., Oscar, M., Bonardo, P., Uribe Roca, M., Fernandez Pardal, M., Reisin, R., Valiensi, S. Tags: Cerebrovascular Disease: Risk Factors and Prevention Source Type: research