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Source: Neurology
Condition: Headache

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Total 267 results found since Jan 2013.

Neurologic features of Hutchinson-Gilford progeria syndrome after lonafarnib treatment
Conclusions: This study provides preliminary evidence that lonafarnib therapy may improve neurologic status of children with HGPS. To address this question, we have incorporated prospective neuroimaging and neurologic assessments as measures in subsequent studies involving children with HGPS. Classification of evidence: This study provides Class IV evidence that lonafarnib 115–150 mg/m2 for 24 to 29 months reduces the prevalence of stroke and TIA and the prevalence and frequency of headache over the treatment period.
Source: Neurology - July 29, 2013 Category: Neurology Authors: Ullrich, N. J., Kieran, M. W., Miller, D. T., Gordon, L. B., Cho, Y.-J., Silvera, V. M., Giobbie-Hurder, A., Neuberg, D., Kleinman, M. E. Tags: Other cerebrovascular disease/ Stroke, All Clinical trials, Class IV ARTICLE Source Type: research

Teaching NeuroImages: Perfusion imaging of cerebral hyperperfusion syndrome following revascularization
A 69-year-old man developed acute-onset confusion and hypertension with systolic pressures in the 160s 1 day after carotid endarterectomy for right facial droop from left hemispheric lacunar infarcts. CT perfusion (figure, A–D) demonstrated findings consistent with cerebral hyperperfusion syndrome (CHS) following revascularization. CHS is caused by loss of autoregulation, hypertension, and ischemia-reperfusion injury resulting in increased regional blood flow and vascular congestion.1 CHS following revascularization may present as ipsilateral headache, focal seizure, or neurologic deficit. Nonperfusion imaging may sh...
Source: Neurology - July 22, 2013 Category: Neurology Authors: Kalra, V. B., Rao, B., Malhotra, A. Tags: CT, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Arteriovenous fistula after ventriculostomy in aneurysmal subarachnoid hemorrhage
A 66-year-old woman was found unresponsive after complaining of severe headache several days prior. She was comatose upon initial evaluation and a cranial CT revealed diffuse subarachnoid hemorrhage. A right posterior communicating artery aneurysm (figure, A, arrow) was successfully treated with endovascular embolization. Conventional angiography performed 7 days following ventriculostomy placement for hydrocephalus demonstrated interval development of a traumatic arteriovenous fistula (AVF) filling by the middle meningeal artery (figure, C, D, arrow). The AVF was treated with intra-arterial embolization. Ventriculostomy-a...
Source: Neurology - June 3, 2013 Category: Neurology Authors: Meisel, K., Yee, A., Stout, C., Kim, W., Cooke, D., Halbach, V. Tags: All Cerebrovascular disease/Stroke, Arteriovenous malformation, Subarachnoid hemorrhage NEUROIMAGES Source Type: research

Teaching NeuroImages: Vein of Galen aneurysm mimicking pineal mass in a young adult
A 22-year-old man presented with intractable progressive headaches over 2 months. Noncontrast head CT and contrast-enhanced MRI scan revealed a hyperdense pineal-based mass (figure, A and B). Arteriogram was normal (figure, C and D).
Source: Neurology - May 27, 2013 Category: Neurology Authors: Gokhale, S., Laskowitz, D. T. Tags: All Cerebrovascular disease/Stroke, Arteriovenous malformation RESIDENT AND FELLOW SECTION Source Type: research

Incidence and prevalence of treated epilepsy among poor health and low-income Americans
Conclusions: The Medicaid population has a high incidence and prevalence of epilepsy, in an order of magnitude greater than that reported in the US general population. This indigent population carries a disproportionate amount of the epilepsy burden and deserves more attention for its health care needs and support services.
Source: Neurology - May 20, 2013 Category: Neurology Authors: Kaiboriboon, K., Bakaki, P. M., Lhatoo, S. D., Koroukian, S. Tags: Cohort studies, Prevalence studies, Incidence studies, All Epilepsy/Seizures ARTICLE Source Type: research

Syncope and orthostatic intolerance increase risk of brain lesions in migraineurs and controls
Conclusions: Frequent syncope, orthostatic intolerance, and migraine independently increase the risk of white matter lesions, particularly in females.
Source: Neurology - May 20, 2013 Category: Neurology Authors: Kruit, M. C., Thijs, R. D., Ferrari, M. D., Launer, L. J., van Buchem, M. A., van Dijk, J. G. Tags: Migraine, MRI, All Cerebrovascular disease/Stroke, Syncope, Risk factors in epidemiology ARTICLE Source Type: research

Background of the Sociedad Neurologica Argentina: Current state and concerns about neurologic education
Neurology in Argentina emerged toward the end of the 19th century, following the origin of the specialty in Europe. Its development can be divided into 3 periods. The first is the specialty of neurology as part of internal medicine. Doctoral theses and publication about neurologic topics are found early in the history of medicine, but merged into internal medicine. The second period is the foundation of clinical neurology under the typical European influence, mainly French, when the first neurologists appear. This period started in 1885 with the creation of the Hospital San Roque de Buenos Aires' first nervous diseases dep...
Source: Neurology - May 20, 2013 Category: Neurology Authors: Correale, J., Allegri, R. F., Pelli-Noble, R. F. Tags: History of Neurology, CME, Methods of education GLOBAL PERSPECTIVES Source Type: research

Teaching NeuroImages: Treatment-resistant rapidly progressive amyloid {beta}-related angiitis
A 76-year-old woman presented with 1 month of progressive aphasia, headache, and subsequent right hemiparesis. Initial brain MRI showed a punctate infarct (figure 1, A and C). Susceptibility-weighted imaging was unremarkable. A repeat study 16 days later demonstrated bihemispheric infarcts with multifocal attenuation of intracranial vessels on magnetic resonance angiography (figure 1, B and D). CSF showed a lymphocytic pleocytosis (101 leukocytes/µL) and elevated protein (480 mg/dL). Brain biopsy showed granulomatous angiitis with amyloid deposition and fibrinoid necrosis surrounded by inflammatory cells (figure 2). ...
Source: Neurology - April 29, 2013 Category: Neurology Authors: Porter, M., Newey, C. R., Toth, G. Tags: MRI, Other cerebrovascular disease/ Stroke, Alzheimer's disease, Infarction RESIDENT AND FELLOW SECTION Source Type: research

Do severe headaches portend greater stroke risk following CRT for childhood brain tumor?
Children with brain tumors are more likely to survive, with survival rates improving consistently over several decades and well over 70% of patients now surviving 5 years from diagnosis.1 The vast majority of these children will become long-term survivors. As cure rates improve, a greater focus has been placed on enduring patient health after cancer treatment.
Source: Neurology - April 15, 2013 Category: Neurology Authors: Heyer, G. L., Mack, K. J. Tags: Childhood stroke, Pediatric headache, All Cerebrovascular disease/Stroke, Primary brain tumor, All Pediatric EDITORIALS Source Type: research

Headache as a risk factor for neurovascular events in pediatric brain tumor patients
Conclusions: Severe recurrent headache appears to be a risk factor or predictor for subsequent cerebral ischemia in pediatric brain tumor survivors treated with radiation. This finding has clinical implications for both monitoring survivors and targeting a specific population for primary stroke prevention.
Source: Neurology - April 15, 2013 Category: Neurology Authors: Kranick, S. M., Campen, C. J., Kasner, S. E., Kessler, S. K., Zimmerman, R. A., Lustig, R. A., Phillips, P. C., Beslow, L. A., Ichord, R., Fisher, M. J. Tags: Childhood stroke, Pediatric headache, All Cerebrovascular disease/Stroke, Primary brain tumor, All Pediatric ARTICLE Source Type: research

Clinical Reasoning: A 44-year-old woman with headache followed by sudden neurologic decline
A 44-year-old woman with a history of migraines and idiopathic intracranial hypertension presented to the emergency room with 1 day of headache and nausea. She had been otherwise healthy with no sick contacts. She was afebrile without nuchal rigidity, rash, or cardiac murmur, and her neurologic examination was normal. Migraine therapy was initiated with IV prochlorperazine, ketorolac, and magnesium. Two hours later, she developed fever (101.4°F) and confusion, continually stating, "It hurts," but unable to answer questions or follow commands despite an otherwise unremarkable examination. Noncontrast head CT demonstrate...
Source: Neurology - March 25, 2013 Category: Neurology Authors: Berkowitz, A. L., Kimchi, E. Y., Hwang, D. Y., Vaitkevicius, H., Henderson, G. V., Feske, S. K., Chou, S. H.- Y. Tags: Hydrocephalus, Stroke in young adults, Meningitis, Critical care RESIDENT AND FELLOW SECTION Source Type: research

Use of ACEI in Migraine Prophylaxis: Why We Don't Look Back? (P01.092)
CONCLUSIONS: ACEI have a lower profile of side effects compared to other blood pressure medications currently used in migraine prophylaxis. The benefits with ACEI recognized in the management of congestive heart failure, hypertension associated with diabetes and secondary stroke prevention maybe can be extrapolated to a younger population. Early initiation of an ACEI in patients with migraine attacks can possibly reduce the incidence of stroke in a population at a higher risk of it later in life.Disclosure: Dr. Delgado has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Delgado, A. Tags: P01 Headache: Clinical Presentation and Therapeutics Source Type: research

Pontine Infarction as a Complication of Basilar-Type Migraine Status Migrainosus (P01.093)
CONCLUSIONS: This patient presents a diagnostic dilemma, since her stroke symptoms were not part of her typical aura syndrome and therefore does not fulfill ICHD-2 criteria for migrainous infarction. These restrictions on what constitutes a bona fide migrainous infarction may improve specificity at the expense of sensitivity, potentially underestimating the role of migraine in stroke etiology.Disclosure: Dr. Vollbracht's family owns stock and/or stock options in Allergan, Inc. Dr. Robbins has nothing to disclose. Dr. Kister has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Vollbracht, S., Robbins, M., Kister, I. Tags: P01 Headache: Clinical Presentation and Therapeutics Source Type: research

Presenting Symptoms for the Identification of Acute Stroke and Transient Ischemic Attack in the Emergency Department (P01.241)
CONCLUSIONS: Whether the Patients were diagnosed as definite stroke or not was significantly associated with presenting symptoms of our UTPS code system. The proper selection of presenting symptom for assessment tool used by emergency department staff may be important to improve its performance in acute stroke response system.Disclosure: Dr. Cho has nothing to disclose. Dr. Baek has nothing to disclose. Dr. Yu has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Cho, K.-H., Baek, S.-H., Yu, S.-W. Tags: P01 Cerebrovascular Disease I Source Type: research

Acute Stroke in Young Women Taking Phentermine (P01.249)
CONCLUSIONS: We present here two patients with mild underlying cerebrovascular risk factors who presented with acute stroke after taking diet pills containing phentermine. The public should be aware of the possible association between stroke and phentermine. More long-term outcomes research is necessary to understand the safety of phentermine-containing diet pills. Patients with cerebrovascular risk factors should be cautious about using Phentermine containing diet pills.Disclosure: Dr. Smit has nothing to disclose. Dr. Cutting has received personal compensation for activities with F1000. Dr. Conners has nothing to disclos...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Smit, L., Cutting, S., Conners, J., Lee, V., Song, S. Tags: P01 Cerebrovascular Disease I Source Type: research