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Condition: Aortic Aneurysm
Therapy: Corticosteroid Therapy
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Response to: 'Biologic agents for giant cell arteritis: treat to target by Moiseev et al
We thank Moiseev et al for their interest in our study of ustekinumab in giant cell arteritis (GCA).1 2 Our pilot study reported promising initial results from the use of ustekinumab in GCA.1 GCA is a potentially devastating disease with cranial ischaemic complications such as blindness and stroke occurring in 20%–25% of patients.3 While corticosteroids are effective in reducing the risk of cranial ischaemic complications, they do not fully extinguish the vascular inflammation in patients with GCA4–6 with consequent risk of disease relapse and longer-term consequences such as aortic aneurysms.7 8 Furthermore, c...
Source: Annals of the Rheumatic Diseases - August 9, 2016 Category: Rheumatology Authors: Conway, R., Molloy, E. S. Tags: Electronic pages Source Type: research
