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Functional performance, nutritional status, and body composition in ambulant community-dwelling individuals 1–3 years after suffering from a cerebral infarction or intracerebral bleeding
Conclusions: Nutritional disorders, i.e., obesity, sarcopenia, or risk for malnutrition, were observed in about one-third of individuals 1 year after stroke. Risk for malnutrition, self-reported physical activity, and age were related to mobility (SPPB), whereas fat-free mass (FFM) and fat mass (FM) were not. Nutrition and exercise treatment could be further evaluated as rehabilitation opportunities after stroke.
Source: Epidemiologic Perspectives and Innovations - February 19, 2016 Category: Epidemiology Authors: Birgit VahlbergLena ZetterbergBirgitta LindmarkKarin HellströmTommy Cederholm Source Type: research

Development of a computerised decision aid for thrombolysis in acute stroke care
Conclusions: Our structured development process led to the development of a gamma prototype computerised decision aid. Initial evaluation has demonstrated reasonable acceptability of COMPASS amongst patients, relatives and clinicians. The impact of COMPASS on clinical outcomes requires wider prospective evaluation in clinical settings.
Source: Epidemiologic Perspectives and Innovations - February 7, 2015 Category: Epidemiology Authors: Darren FlynnDaniel J NesbittGary A FordPeter McMeekinHelen RodgersChristopher PriceChristian KrayRichard G Thomson Source Type: research

Sex differences in clinical characteristics and outcomes after intracerebral haemorrhage: results from a 12-month prospective stroke registry in Nanjing, China
This study aimed to investigate the sex differences in clinical characteristics, severity and outcomes of Chinese ICH patients. Methods: The Nanjing First Hospital stroke registry was a hospital-based registry of stroke patients with 1-year prospective follow-up. From 2004 to 2008, a total of 651 consecutively recruited patients with acute ICH were enrolled. Primary outcome was death or dependency defined as a modified Rankin Scale score of 3?6 at 12 months. Multivariable logistic regression analyses were performed to determine whether there were sex differences in clinical outcomes after ICH. Clinically important and biol...
Source: Epidemiologic Perspectives and Innovations - September 4, 2014 Category: Epidemiology Authors: Junshan ZhouYingdong ZhangHisatomi ArimaYanxia ZhaoHongdong ZhaoDanni ZhengYouyong TianYukai LiuQing HuangJie Yang Source Type: research

MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial
DiscussionIf IAT leads to a 10% absolute reduction in poor outcome after stroke, careful implementation of the intervention could save approximately 1% of all new stroke cases from death or disability annually.Trial registration: NTR1804 (7 May 2009)/ISRCTN10888758 (24 July 2012).
Source: Epidemiologic Perspectives and Innovations - September 1, 2014 Category: Epidemiology Authors: Puck SS FransenDebbie BeumerOlvert A BerkhemerLucie A van den BergHester LingsmaAad van der LugtWim H van ZwamRobert J van OostenbruggeYvo BWEM RoosCharles B MajoieDiederik WJ Dippel Source Type: research

Impact of stated barriers on proposed warfarin prescription for atrial fibrillation: a survey of Canadian physicians
Background: Atrial fibrillation (AF) is a common cardiac arrhythmia, and leading cause of ischemic stroke. Despite proven effectiveness, warfarin remains an under-used treatment in atrial fibrillation patients. We sought to study, across three physician specialties, a range of factors that have been argued to have a disproportionate effect on treatment decisions. Methods: Cross-sectional survey of Canadian Family Doctors (FD: n = 500), Geriatricians (G: n = 149), and Internal Medicine specialists (IMS: n = 500). Of these, 1032 physicians were contactable, and 335 completed and usable responses were received. Survey questio...
Source: Epidemiologic Perspectives and Innovations - June 23, 2014 Category: Epidemiology Authors: Stuart G NichollsJamie C BrehautRubab G ArimKelly CarrollRichard PerezKaveh G ShojaniaJeremy M GrimshawRoy Poses Source Type: research