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Reliability of effective arterial elastance using peripheral arterial pressure as surrogate for left ventricular end-systolic pressure
AbstractTo compare the effective arterial elastance (Ea) obtained from the arterial pressure with Ea calculated from left-ventricular (LV) pressure –volume analysis. Experimental study. LV pressure–volume data was obtained with a conductance catheter and arterial pressures were measured via a fluid-filled catheter placed in the proximal aorta, femoral and radial arteries. Ea was calculated as LV end-systolic pressure (ESP)/stroke volume (SV ). Experimental protocol consisted sequentially changing afterload (phenylephrine/nitroprusside), preload (bleeding/fluid), and contractility (esmolol/dobutamine). 90% of systolic p...
Source: Journal of Clinical Monitoring and Computing - December 14, 2018 Category: Information Technology Source Type: research

New Cochrane health evidence challenges belief that omega 3 supplements reduce risk of heart disease, stroke or death
New evidence published today shows there is little or no effect of omega 3 supplements on our risk of experiencing heart disease, stroke or death.Omega 3 is a type of fat. Small amounts of omega 3 fats are essential for good health, and they can be found in the food that we eat. The main types of omega 3 fatty acids are; alpha ­linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).  ALA is normally found in fats from plant foods, such as nuts and seeds (walnuts and rapeseed are rich sources). EPA and DHA, collectively called long chain omega 3 fats, are naturally found in fatty fish, such as s...
Source: Cochrane News and Events - July 16, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

The Effect of a Clinical Decision Support System on Improving Adherence to Guideline in the Treatment of Atrial Fibrillation: An Interrupted Time Series Study
This study had an interrupted time series design. The adherence to the guideline was assessed at fortnightly (two weeks) intervals from January 2016 to January 2017, 6  months before and 6 months after intervention. Newly diagnosed patients with AF were included in the offices of ten cardiologists. Stroke and major bleeding risks were calculated by the CDSS which was implemented via a mobile application. Treatment recommendations based on the guideline were show n to cardiologists. The segmented regression model was used to evaluate the effect of CDSS on level and trend of guideline adherence for the treatment of AF. In ...
Source: Journal of Medical Systems - December 23, 2017 Category: Information Technology Source Type: research

Use of electronic healthcare records to identify complex patients with atrial fibrillation for targeted intervention
Discussion: We developed and tested a set of algorithms to identify AF patients and known risk factors for stroke and major bleeding using EHR data. Algorithms such as these can be built into EHR systems to facilitate informed decision making and help shift population health management efforts towards patients with the greatest need.
Source: Journal of the American Medical Informatics Association - July 2, 2016 Category: Information Technology Authors: Wang, S. V., Rogers, J. R., Jin, Y., Bates, D. W., Fischer, M. A. Tags: Research and Applications Source Type: research

Evaluation of near infrared spectroscopy for detecting the β blocker-induced decrease in cerebral oxygenation during hemodilution in a swine model
Abstract β blockers reduce cerebral oxygenation after acute hemodilution and may contribute to the incidence of stroke when used perioperatively. The goal of the study was to investigate whether cerebral tissue oxygenation using near infrared spectroscopy can detect the β blocker-induced decrease in cerebral oxygenation depending on the severity of hemodilution and/or the dose of β blockers. Animals were anesthetized with 2 % isoflurane and randomly assigned to a landiolol or esmolol group. After baseline measurement, landiolol or esmolol was administered at 40 µg/kg/min for 20 min, increased to 200 µg/kg...
Source: Journal of Clinical Monitoring and Computing - February 10, 2015 Category: Information Technology Source Type: research

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