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The role of central sensitization in shoulder pain: A systematic literature review
Hyperexcitability of the central nervous system has been suggested to play an important role in pain experienced by patients with unilateral shoulder pain. A systematic literature review following the PRISMA guidelines was performed to evaluate the existing evidence related to the presence of central sensitization in patients with unilateral shoulder pain of different etiologies including those with chronic subacromial impingement syndrome. Studies addressing neuropathic pain (e.g. post-stroke shoulder pain) were not considered.
Source: Seminars in Arthritis and Rheumatism - November 13, 2014 Category: Rheumatology Authors: M.N. Sanchis, E. Lluch, J. Nijs, F. Struyf, M. Kangasperko Source Type: research

Cardiovascular events in ankylosing spondylitis. An updated meta-analysis
This study aims to assess the risk of myocardial infarction (MI) and stroke in AS patients.
Source: Seminars in Arthritis and Rheumatism - October 17, 2014 Category: Rheumatology Authors: Sylvain Mathieu, Bruno Pereira, Martin Soubrier Source Type: research

Cardiovascular events in ankylosing spondylitis: An updated meta-analysis
This study aims to assess the risk of myocardial infarction (MI) and stroke in AS patients.
Source: Seminars in Arthritis and Rheumatism - October 17, 2014 Category: Rheumatology Authors: Sylvain Mathieu, Bruno Pereira, Martin Soubrier Source Type: research

Cardiovascular thromboembolic events associated with febuxostat: Investigation of cases from the FDA adverse event reporting system database
Conclusion: AERS indicated potential signals of febuxostat-associated cardiovascular thromboembolic events. AERS is not capable of establishing the causal link and detecting the true frequency of an adverse event associated with a drug. The positive IC value found in this study merits continued surveillance and assessment of cardiovascular thromboembolic events associated with Febuxostat.
Source: Seminars in Arthritis and Rheumatism - January 28, 2013 Category: Rheumatology Authors: Pranav K. Gandhi, William M. Gentry, Michael B. Bottorff Source Type: research