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Source: Journal of Clinical Neurology

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Total 1060 results found since Jan 2013.

Acute Ischemic Stroke Caused by Intracranial Atherosclerosis Associated With Lorlatinib-Induced Dyslipidemia
J Clin Neurol. 2023 Jan;19(1):90-92. doi: 10.3988/jcn.2023.19.1.90.NO ABSTRACTPMID:36606651 | DOI:10.3988/jcn.2023.19.1.90
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Jaechun Hwang Yonghyun Lee Kyunghun Kang Mi-Yeon Eun Source Type: research

Relationship Between MicroRNA Signature and Arterial Stiffness in Patients With Ischemic Stroke
CONCLUSIONS: The expression level of let-7i was independently related to arterial stiffness in patients with cerebral infarction, suggesting that it plays a pathophysiological role in atherosclerosis.PMID:36606643 | DOI:10.3988/jcn.2023.19.1.28
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Sang-Jin Lee Jeong-Min Kim Eun Sun Lee Kwang-Yeol Park Hye Ryoun Kim Source Type: research

Update on the Epidemiology, Pathogenesis, and Biomarkers of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
J Clin Neurol. 2023 Jan;19(1):12-27. doi: 10.3988/jcn.2023.19.1.12.ABSTRACTCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral small blood vessels. It is caused by mutations in the NOTCH3 gene on chromosome 19, and more than 280 distinct pathogenic mutations have been reported to date. CADASIL was once considered a very rare disease with an estimated prevalence of 1.3-4.1 per 100,000 adults. However, recent large-scale genomic studies have revealed a high prevalence of pathogenic NOTCH3 variants among the general populati...
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Yumi Yamamoto Yi-Chu Liao Yi-Chung Lee Masafumi Ihara Jay Chol Choi Source Type: research

Acute Ischemic Stroke Caused by Intracranial Atherosclerosis Associated With Lorlatinib-Induced Dyslipidemia
J Clin Neurol. 2023 Jan;19(1):90-92. doi: 10.3988/jcn.2023.19.1.90.NO ABSTRACTPMID:36606651 | DOI:10.3988/jcn.2023.19.1.90
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Jaechun Hwang Yonghyun Lee Kyunghun Kang Mi-Yeon Eun Source Type: research

Relationship Between MicroRNA Signature and Arterial Stiffness in Patients With Ischemic Stroke
CONCLUSIONS: The expression level of let-7i was independently related to arterial stiffness in patients with cerebral infarction, suggesting that it plays a pathophysiological role in atherosclerosis.PMID:36606643 | DOI:10.3988/jcn.2023.19.1.28
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Sang-Jin Lee Jeong-Min Kim Eun Sun Lee Kwang-Yeol Park Hye Ryoun Kim Source Type: research

Update on the Epidemiology, Pathogenesis, and Biomarkers of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
J Clin Neurol. 2023 Jan;19(1):12-27. doi: 10.3988/jcn.2023.19.1.12.ABSTRACTCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral small blood vessels. It is caused by mutations in the NOTCH3 gene on chromosome 19, and more than 280 distinct pathogenic mutations have been reported to date. CADASIL was once considered a very rare disease with an estimated prevalence of 1.3-4.1 per 100,000 adults. However, recent large-scale genomic studies have revealed a high prevalence of pathogenic NOTCH3 variants among the general populati...
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Yumi Yamamoto Yi-Chu Liao Yi-Chung Lee Masafumi Ihara Jay Chol Choi Source Type: research

Relationship Between MicroRNA Signature and Arterial Stiffness in Patients With Ischemic Stroke
CONCLUSIONS: The expression level of let-7i was independently related to arterial stiffness in patients with cerebral infarction, suggesting that it plays a pathophysiological role in atherosclerosis.PMID:36606643 | DOI:10.3988/jcn.2023.19.1.28
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Sang-Jin Lee Jeong-Min Kim Eun Sun Lee Kwang-Yeol Park Hye Ryoun Kim Source Type: research

Update on the Epidemiology, Pathogenesis, and Biomarkers of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
J Clin Neurol. 2023 Jan;19(1):12-27. doi: 10.3988/jcn.2023.19.1.12.ABSTRACTCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral small blood vessels. It is caused by mutations in the NOTCH3 gene on chromosome 19, and more than 280 distinct pathogenic mutations have been reported to date. CADASIL was once considered a very rare disease with an estimated prevalence of 1.3-4.1 per 100,000 adults. However, recent large-scale genomic studies have revealed a high prevalence of pathogenic NOTCH3 variants among the general populati...
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Yumi Yamamoto Yi-Chu Liao Yi-Chung Lee Masafumi Ihara Jay Chol Choi Source Type: research

Acute Ischemic Stroke Caused by Intracranial Atherosclerosis Associated With Lorlatinib-Induced Dyslipidemia
J Clin Neurol. 2023 Jan;19(1):90-92. doi: 10.3988/jcn.2023.19.1.90.NO ABSTRACTPMID:36606651 | DOI:10.3988/jcn.2023.19.1.90
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Jaechun Hwang Yonghyun Lee Kyunghun Kang Mi-Yeon Eun Source Type: research

Relationship Between MicroRNA Signature and Arterial Stiffness in Patients With Ischemic Stroke
CONCLUSIONS: The expression level of let-7i was independently related to arterial stiffness in patients with cerebral infarction, suggesting that it plays a pathophysiological role in atherosclerosis.PMID:36606643 | DOI:10.3988/jcn.2023.19.1.28
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Sang-Jin Lee Jeong-Min Kim Eun Sun Lee Kwang-Yeol Park Hye Ryoun Kim Source Type: research

Update on the Epidemiology, Pathogenesis, and Biomarkers of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
J Clin Neurol. 2023 Jan;19(1):12-27. doi: 10.3988/jcn.2023.19.1.12.ABSTRACTCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral small blood vessels. It is caused by mutations in the NOTCH3 gene on chromosome 19, and more than 280 distinct pathogenic mutations have been reported to date. CADASIL was once considered a very rare disease with an estimated prevalence of 1.3-4.1 per 100,000 adults. However, recent large-scale genomic studies have revealed a high prevalence of pathogenic NOTCH3 variants among the general populati...
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Yumi Yamamoto Yi-Chu Liao Yi-Chung Lee Masafumi Ihara Jay Chol Choi Source Type: research

Relationship Between MicroRNA Signature and Arterial Stiffness in Patients With Ischemic Stroke
CONCLUSIONS: The expression level of let-7i was independently related to arterial stiffness in patients with cerebral infarction, suggesting that it plays a pathophysiological role in atherosclerosis.PMID:36606643 | DOI:10.3988/jcn.2023.19.1.28
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Sang-Jin Lee Jeong-Min Kim Eun Sun Lee Kwang-Yeol Park Hye Ryoun Kim Source Type: research

Update on the Epidemiology, Pathogenesis, and Biomarkers of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
J Clin Neurol. 2023 Jan;19(1):12-27. doi: 10.3988/jcn.2023.19.1.12.ABSTRACTCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disorder of the cerebral small blood vessels. It is caused by mutations in the NOTCH3 gene on chromosome 19, and more than 280 distinct pathogenic mutations have been reported to date. CADASIL was once considered a very rare disease with an estimated prevalence of 1.3-4.1 per 100,000 adults. However, recent large-scale genomic studies have revealed a high prevalence of pathogenic NOTCH3 variants among the general populati...
Source: Journal of Clinical Neurology - January 6, 2023 Category: Neurology Authors: Yumi Yamamoto Yi-Chu Liao Yi-Chung Lee Masafumi Ihara Jay Chol Choi Source Type: research

Vessel Wall Changes on Serial High-Resolution MRI and the Use of Cilostazol in Patients With Adult-Onset Moyamoya Disease
CONCLUSIONS: Adult-onset MMD induces progressive shrinkage of large intracranial arteries, which cilostazol treatment may prevent. Further randomized clinical trials are warranted.TRIAL REGISTRATION: ClinicalTrials.gov identifier NCT02074111.PMID:36367058 | DOI:10.3988/jcn.2022.18.6.610
Source: Journal of Clinical Neurology - November 11, 2022 Category: Neurology Authors: Jae Youn Kim Hyung Jun Kim Eun-Hyeok Choi Kwang Hyun Pan Jong-Won Chung Woo-Keun Seo Gyeong-Moon Kim Tae Keun Jee Je Young Yeon Jong-Soo Kim Seung-Chyul Hong Min-Jung Seong Jihoon Cha Keon Ha Kim Pyoung Jeon Oh Young Bang Source Type: research