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Synthesis of Star Polymers by RAFT Polymerization as Versatile Nanoparticles for Biomedical Applications
Jinming Hu, Ruirui Qiao, Michael R. Whittaker, John F. Quinn, Thomas P. Davis Synthesis of star polymers using reversible addition–fragmentation chain transfer (RAFT) polymerization through core-first and arm-first preparation are outlined. Biomedical applications of the resulting star polymers in controlled delivery of chemotherapeutic agents, protein inhibitors, signalling molecules, siRNA, and in constructing macromolecular magnetic resonance imaging (MRI) contrast agents and fluorescent imaging agents, and theranostic vectors are discussed.
Source: Australian Journal of Chemistry - September 13, 2017 Category: Chemistry Authors: Jinming Hu Ruirui Qiao Michael R. Whittaker John F. Quinn Thomas P. Davis Source Type: research