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Source: Genome Research
Infectious Disease: Fungal Infections
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New signaling pathways govern the host response to C. albicans infection in various niches RESEARCH
Candida albicans, the major invasive fungal pathogen of humans, can cause both debilitating mucosal infections and fatal invasive infections. Understanding the complex nature of the host–pathogen interaction in each of these contexts is essential to developing desperately needed therapies to treat fungal infections. RNA-seq enables a systems-level understanding of infection by facilitating comprehensive analysis of transcriptomes from multiple species (e.g., host and pathogen) simultaneously. We used RNA-seq to characterize the transcriptomes of both C. albicans and human endothelial cells or oral epithelial cells du...
Source: Genome Research - April 9, 2015 Category: Genetics & Stem Cells Authors: Liu, Y., Shetty, A. C., Schwartz, J. A., Bradford, L. L., Xu, W., Phan, Q. T., Kumari, P., Mahurkar, A., Mitchell, A. P., Ravel, J., Fraser, C. M., Filler, S. G., Bruno, V. M. Tags: RESEARCH Source Type: research
