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Infectious Disease: Genital Warts
Drug: Polyethylene Glycol
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PEGylation of lipoplexes: The right balance between cytotoxicity and siRNA effectiveness.
In conclusion, the right balance between cytotoxicity and siRNA effectiveness has been found with the transfection of lipoplexes coated with 20% of Ceramide-PEG2000. This new nanovector could have a high potential against multiple mucosal diseases, such as human papillomavirus-induced genital lesions.
PMID: 27593989 [PubMed - as supplied by publisher]
Source: European Journal of Pharmaceutical Sciences - August 31, 2016 Category: Drugs & Pharmacology Authors: Lechanteur A, Furst T, Evrard B, Delvenne P, Hubert P, Piel G Tags: Eur J Pharm Sci Source Type: research