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Source: Clinical Cancer Research
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MAPK Pathway Inhibitors Sensitize BRAF Mutant Melanoma to an Antibody-Drug Conjugate Targeting GPNMB.
CONCLUSIONS: The combination of MAPK pathway inhibitors with an antibody-drug-conjugate targeting GPNMB is an effective therapeutic option for patients with melanoma.
PMID: 27515299 [PubMed - as supplied by publisher]
Source: Clinical Cancer Research - August 10, 2016 Category: Cancer & Oncology Authors: Rose AA, Annis MG, Frederick DT, Biondini M, Dong Z, Kwong LN, Chin L, Keler T, Hawthorne T, Watson IR, Flaherty KT, Siegel PM Tags: Clin Cancer Res Source Type: research