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Abstract 232: Extracellular matrix components influence prostate tumor cell sensitivity to cancer-preventive agents selenium and green tea polyphenols
Some cancer-preventive agents such as selenium and green tea polyphenols effectively prevent cancer in some cases, but fail in other cases. It could be possible that the cancer-preventive actions of these agents may be altered by the interaction of cancer cells with the extracellular matrix (ECM) components, thus making this an important issue to study. Others have previously cloned a family of human prostate cancer cell lines with a common lineage that show the progression of characteristics from low to high degrees of malignancy and mimic different stages of tumor progression seen in human prostate cancer. For this study...
Source: Cancer Research - September 30, 2014 Category: Cancer & Oncology Authors: Gopalakrishna, R., Fan, T., Deng, R., Rayudu, D., Chen, Z. W., Tzeng, W. S., Gundimeda, U. Tags: Prevention Research Source Type: research