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Source: Biomedical and Environmental Sciences
Drug: Atorvastatin Calcium
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Atorvastatin Attenuates TNF-alpha Production via Heme Oxygenase-1 Pathway in LPS-stimulated RAW264.7 Macrophages
Conclusion Atorvastatin can attenuate LPS-induced TNF-α expression and production by activating HO-1 via the ERK and p38 MAPK pathways, suggesting that atorvastatin can be used in treatment of inflammatory diseases such as sepsis, especially in those with atherosclerotic diseases.
Source: Biomedical and Environmental Sciences - November 9, 2014 Category: Biomedical Science Source Type: research
